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P50317

- PGK_SULSO

UniProt

P50317 - PGK_SULSO

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Protein

Phosphoglycerate kinase

Gene
pgk, SSO0527, C22_024
Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei331 – 3311ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-507-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:SSO0527
ORF Names:C22_024
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Phosphoglycerate kinaseUniRule annotationPRO_0000146071Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0527.

Structurei

3D structure databases

ProteinModelPortaliP50317.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni63 – 664Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiTEYHANT.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50317-1 [UniParc]FASTAAdd to Basket

« Hide

MGDLTIPTMD DIDIQSKKVL LRIDINSPVD ENGKIIDDSR IKAHIGTIKE    50
LINKGNSVVL ISHQGRPGDK DFTSLEEHAK LISKYLDREV IFVDDVIGPY 100
AREMIKKLEN NGILLLDNIR LISEELIEAP PQQHVKSFLV KKLAPLFDIY 150
INDAFATAHR SQPSIVGFPL ALPSAAGRVM EREVSALAKI FNAEDTPKIF 200
TLGGGKVHDT IRIIENLVRK RIADRILTGG LVAELFSVAK GMNLNPKNME 250
ILEKLGILSL IPRARKLLLS GAPIEIPVDY KVEINGNVIE EPASKVTGII 300
KDIGSTTAEI YSSFIKDAKV VVLRGPMGVI EDERFKSGSK SVLKASLEGQ 350
GYVIIGGGHM ISALDEDMKI DSSKVHISTG GGALLLFLSG ERLPALEALS 400
MSVVNSGD 408
Length:408
Mass (Da):44,396
Last modified:October 1, 1996 - v1
Checksum:i9EBF90068315C099
GO

Sequence cautioni

The sequence AAK40847.1 differs from that shown. Reason: Erroneous initiation.
The sequence CAB57772.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X80178 Genomic DNA. Translation: CAA56459.1.
Y18930 Genomic DNA. Translation: CAB57772.1. Different initiation.
AE006641 Genomic DNA. Translation: AAK40847.1. Different initiation.
PIRiH90198.
S63528.
RefSeqiNP_342057.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40847; AAK40847; SSO0527.
GeneIDi1454814.
KEGGisso:SSO0527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X80178 Genomic DNA. Translation: CAA56459.1 .
Y18930 Genomic DNA. Translation: CAB57772.1 . Different initiation.
AE006641 Genomic DNA. Translation: AAK40847.1 . Different initiation.
PIRi H90198.
S63528.
RefSeqi NP_342057.1. NC_002754.1.

3D structure databases

ProteinModelPortali P50317.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273057.SSO0527.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK40847 ; AAK40847 ; SSO0527 .
GeneIDi 1454814.
KEGGi sso:SSO0527.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi TEYHANT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci SSOL273057:GCH2-507-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The phosphoglycerate kinase and glyceraldehyde-3-phosphate dehydrogenase genes from the thermophilic archaeon Sulfolobus solfataricus overlap by 8-bp. Isolation, sequencing of the genes and expression in Escherichia coli."
    Jones C.E., Fleming T.M., Cowan D.A., Littlechild J.A., Piper P.W.
    Eur. J. Biochem. 233:800-808(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiPGK_SULSO
AccessioniPrimary (citable) accession number: P50317
Secondary accession number(s): Q9UWT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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