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P50315 (PGK_HALVA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
OrganismHaloarcula vallismortis (Halobacterium vallismortis)
Taxonomic identifier28442 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146053

Regions

Nucleotide binding357 – 3604ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1161Substrate By similarity
Binding site1561Substrate By similarity
Binding site3311ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P50315 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: ACDD98F8856B490E

FASTA40144,193
        10         20         30         40         50         60 
MMTFQTLDDL DDGQRVLVRL DLNSPVEDGT VQDNRRFDRH AETVKELADR GFEVAVLAHQ 

        70         80         90        100        110        120 
GRPGRDDFVS LDQHADILAD HIDRDVDFVD ETYGPQAIHD IADLDSGDVL VLENTRMCDD 

       130        140        150        160        170        180 
ELPEEDPEVK AQTEFVKTLA GEFDAYINDA YSAAHRSHAS LVGFPLVMDA YAGRVMETEY 

       190        200        210        220        230        240 
EANTAIAEKE FDGQVTMVVG GTKATDVIDV MTHLDEKVDD FLLGGIAGTV PAAAGHPVGY 

       250        260        270        280        290        300 
DIDDANLYDE QWEANSEKIE SMLEDHRDQI TLAVDLAYED ENDDRAEQAV DDIDEKRLSY 

       310        320        330        340        350        360 
LDVGSETLME YSPIIRESEA VFGEGRAGMF EDERFSVGTA GVLEAIADTD CFSVVGGGDT 

       370        380        390        400 
SRAIEMYGME EDEFGHVSIA GGAYIRALTR AQLVGVEVLQ R 

« Hide

References

[1]"Higher-plant chloroplast and cytosolic 3-phosphoglycerate kinases: a case of endosymbiotic gene replacement."
Brinkmann H., Martin W.
Plant Mol. Biol. 30:65-75(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29715 / DSM 3756 / JCM 8877 / NBRC 14741 / NCIMB 2082.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L47295 Genomic DNA. Translation: AAB03731.1.
PIRS65044.

3D structure databases

ProteinModelPortalP50315.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_HALVA
AccessionPrimary (citable) accession number: P50315
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways