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P50314 (PGK_XANFL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
OrganismXanthobacter flavus
Taxonomic identifier281 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeXanthobacter

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146046

Regions

Nucleotide binding354 – 3574ATP By similarity
Region23 – 253Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1191Substrate By similarity
Binding site1521Substrate By similarity
Binding site2021ATP By similarity
Binding site3241ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P50314 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 2492392F0AEBDBF8

FASTA39741,727
        10         20         30         40         50         60 
MIAFRTLDDA VDLADKRVLV RVDLNVPMES GRVTDATRLK AILPTIRDIT GKGGKAVLLA 

        70         80         90        100        110        120 
HLGRPKGRDE SQSLAPVAKA LEGELGRKVA FASDCIGDEA KSAVSRLASG EVIVLENTRF 

       130        140        150        160        170        180 
HAGEEKNAPD FIEALASLGD IYVNDAFSTA HRAHASTEGL ARKLPAYAGR SMESEIEALT 

       190        200        210        220        230        240 
KALEAPQRPV LAVVGGSKVS SKLELLGNLV KKVDILVIGG GMANTFLAAL GKKVGKSLCE 

       250        260        270        280        290        300 
HDLANTARDI LKKAEAAGCE IVLPVDAVVA TEFKANAAHR VTSVDDVKDD EMMLDAGPET 

       310        320        330        340        350        360 
VGIVKQKLDG AKTVVWNGPF GAFEMTPFDA ATVAVARYVG DLTHKGRLLS VAGGGDTVAA 

       370        380        390 
LNHAGTAERF SYVSTAGGAF LEWLEGKALP GVEALRR 

« Hide

References

[1]"The Calvin cycle enzyme phosphoglycerate kinase of Xanthobacter flavus required for autotrophic CO2 fixation is not encoded by the cbb operon."
Meijer W.G.
J. Bacteriol. 176:6120-6126(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: H4-14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U08462 Genomic DNA. Translation: AAA62185.1.
U33064 Genomic DNA. Translation: AAA96748.1.

3D structure databases

ProteinModelPortalP50314.
SMRP50314. Positions 5-396.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_XANFL
AccessionPrimary (citable) accession number: P50314
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways