ID   ASE1_YEAST              Reviewed;         885 AA.
AC   P50275;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-NOV-2009, entry version 58.
DE   RecName: Full=Anaphase spindle elongation protein;
GN   Name=ASE1; OrderedLocusNames=YOR058C; ORFNames=YOR29-09;
OS   Saccharomyces cerevisiae (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=96032267; PubMed=7559759; DOI=10.1083/jcb.130.6.1373;
RA   Pellman D., Bagget M., Tu Y.H., Fink G.R.;
RT   "Two microtubule-associated proteins required for anaphase spindle
RT   movement in Saccharomyces cerevisiae.";
RL   J. Cell Biol. 130:1373-1385(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=97279235; PubMed=9133743;
RX   DOI=10.1002/(SICI)1097-0061(19970330)13:4<379::AID-YEA85>3.3.CO;2-7;
RA   Valens M., Bohn C., Daignan-Fornier B., Dang V.-D.,
RA   Bolotin-Fukuhara M.;
RT   "The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the
RT   presence of two tRNAs and 24 new open reading frames.";
RL   Yeast 13:379-390(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 96604 / S288c / FY1679;
RX   MEDLINE=97313270; PubMed=9169874;
RA   Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W.,
RA   Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R.,
RA   Boyer J., Camasses A., Casamayor A., Casas C., Cheret G.,
RA   Cziepluch C., Daignan-Fornier B., Dang V.-D., de Haan M., Delius H.,
RA   Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F.,
RA   Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A.,
RA   Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA   Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA   Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA   Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J.,
RA   Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P.,
RA   Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M.,
RA   Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R.,
RA   Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S.,
RA   Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A.,
RA   Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M.,
RA   Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C.,
RA   Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S.,
RA   Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL   Nature 387:98-102(1997).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   MEDLINE=22923965; PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A.,
RA   Dephoure N., O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- FUNCTION: Required for anaphase spindle elongation.
CC   -!- MISCELLANEOUS: Present with 556 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the MAP65/ASE1 family.
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DR   EMBL; U20235; AAA75026.1; -; Genomic_DNA.
DR   EMBL; Z74966; CAA99251.1; -; Genomic_DNA.
DR   EMBL; Z70678; CAA94543.1; -; Genomic_DNA.
DR   PIR; S59660; S59660.
DR   RefSeq; NP_116582.1; -.
DR   DIP; DIP:7343N; -.
DR   IntAct; P50275; 1.
DR   STRING; P50275; -.
DR   PRIDE; P50275; -.
DR   Ensembl; YOR058C; YOR058C; YOR058C; Saccharomyces cerevisiae.
DR   GeneID; 854223; -.
DR   GenomeReviews; Y13140_GR; YOR058C.
DR   KEGG; sce:YOR058C; -.
DR   NMPDR; fig|4932.3.peg.5801; -.
DR   CYGD; YOR058c; -.
DR   SGD; S000005584; ASE1.
DR   HOGENOM; P50275; -.
DR   OMA; RNSHKIL; -.
DR   NextBio; 976092; -.
DR   ArrayExpress; P50275; -.
DR   Genevestigator; P50275; -.
DR   GermOnline; YOR058C; Saccharomyces cerevisiae.
DR   GO; GO:0005880; C:nuclear microtubule; IDA:SGD.
DR   GO; GO:0051233; C:spindle midzone; IDA:SGD.
DR   GO; GO:0008017; F:microtubule binding; IDA:SGD.
DR   GO; GO:0007109; P:cytokinesis, completion of separation; IMP:SGD.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:SGD.
DR   GO; GO:0000092; P:mitotic anaphase B; IMP:SGD.
DR   GO; GO:0000022; P:mitotic spindle elongation; IMP:SGD.
DR   GO; GO:0043148; P:mitotic spindle stabilization; IMP:SGD.
DR   GO; GO:0051255; P:spindle midzone assembly; IMP:SGD.
DR   GO; GO:0000073; P:spindle pole body separation; IGI:SGD.
DR   InterPro; IPR007145; MAP65_ASE1.
DR   PANTHER; PTHR19321; MAP65_ASE1; 1.
DR   Pfam; PF03999; MAP65_ASE1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Microtubule.
FT   CHAIN         1    885       Anaphase spindle elongation protein.
FT                                /FTId=PRO_0000064694.
SQ   SEQUENCE   885 AA;  101624 MW;  6EDE11E887E89207 CRC64;
     METATSSPLP IKSRRNSENS GSTTVIPHMN PSLATPLTVS TMVNQSNSKE FMKLTPVRIR
     DFGSPLKNVS TNYHFLDSEN GKGNTMDNMY RENFILISKD LEKLLENLNV IYQNIGYSNT
     EIITKEKIIF TTISNSIKQF FEQADEELKR LSAENGIEQD ILNNILERIN DPSGIKTIPD
     LYIRNAILLQ ESKTVPQSPK KPLSLLSKKA ALDTAKKFVL GSFLPRLRDY LKSLITLKHL
     IQSVKENLPG LTEADNEAIA EFPELSTLTA YLLQIENGKG DIGLSMKFII DNRKDILKGS
     AFKTINEESV KHMNEVIKIY EEEYERRFKS VLTKKVSISS ICEQLGTPLA TLIGEDFEQD
     LRSYGEEENS TSEIPNFHPV DRERMSKIDI TLEKLQAIHK ERADKKRLLM EQCQKLWTRL
     KISQEYIKTF MRNNSSLSTE SLGRISKEVM RLEAMKKKLI KKLISDSWDK IQELWRTLQY
     SEESRSKFII VFEELRNSAT TLQEDELLLE TCENELKRLE EKLTLYKPIL KLISDFESLQ
     EDQEFLERSS KDSSRLLSRN SHKILLTEEK MRKRITRHFP RVINDLRIKL EEADGLFDQP
     FLFKGKPLSE AIDIQQQEIE AKYPRCRVRM QRSKKGKCGA NKENKVIKNT FKATESSIRV
     PIGLNLNDAN ITYKTPSKKT IQGLTKNDLS QENSLARHMQ GTTKLSSPNR RATRLLAPTV
     ISRNSKGNIE RPTLNRNRSS DLSSSPRINH THGEHAVKPR QLFPIPLNKV DTKGSHIPQL
     TKEKALELLK RSTGTTGKEN VRSPERKSSL EDYAQKLSSP YKEPEHSIYK LSMSPEGKFQ
     LNIQQKDIES GFDDTSMMED ENDKDFITWK NEQVSKLNGF SFTDI
//