P50275 (ASE1_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 75.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Anaphase spindle elongation protein | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||||
| Taxonomic identifier | 559292 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 885 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Required for anaphase spindle elongation. |
| Subcellular location | Cytoplasm › cytoskeleton › spindle Probable. |
| Miscellaneous | Present with 556 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | Belongs to the MAP65/ASE1 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm Cytoskeleton Microtubule |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | cytokinesis, completion of separation Inferred from mutant phenotype. Source: SGD microtubule bundle formationInferred from direct assay. Source: SGD mitotic anaphase BInferred from mutant phenotype Ref.1. Source: SGD mitotic spindle elongationInferred from mutant phenotype. Source: SGD mitotic spindle stabilizationInferred from mutant phenotype. Source: SGD spindle midzone assemblyInferred from mutant phenotype. Source: SGD |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW nuclear microtubuleInferred from direct assay Ref.1. Source: SGD spindle midzoneInferred from direct assay Ref.1. Source: SGD |
| Molecular function | microtubule binding Inferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 885 | 885 | Anaphase spindle elongation protein | PRO_0000064694 | |||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae." Pellman D., Bagget M., Tu Y.H., Fink G.R. J. Cell Biol. 130:1373-1385(1995) [PubMed: 7559759] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames." Valens M., Bohn C., Daignan-Fornier B., Dang V.-D., Bolotin-Fukuhara M. Yeast 13:379-390(1997) [PubMed: 9133743] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [3] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. Kleine K.Nature 387:98-102(1997) [PubMed: 9169874] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [4] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U20235 Genomic DNA. Translation: AAA75026.1. Z74966 Genomic DNA. Translation: CAA99251.1. Z70678 Genomic DNA. Translation: CAA94543.1. BK006948 Genomic DNA. Translation: DAA10837.1. |
| PIR | S59660. |
| RefSeq | NP_116582.1. NM_001183477.1. |
3D structure databases | |
| ProteinModelPortal | P50275. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-7343N. |
| IntAct | P50275. 1 interaction. |
| MINT | MINT-2780814. |
| STRING | P50275. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YOR058C; YOR058C; YOR058C. |
| GeneID | 854223. |
| KEGG | sce:YOR058C. |
| NMPDR | fig|4932.3.peg.5801. |
Organism-specific databases | |
| CYGD | YOR058c. |
| SGD | S000005584. ASE1. |
Phylogenomic databases | |
| eggNOG | fuNOG05439. |
| GeneTree | EFGT00050000001124. |
| HOGENOM | HBG202821. |
| OMA | RNSHKIL. |
| OrthoDB | EOG4T4H3R. |
Gene expression databases | |
| ArrayExpress | P50275. |
| Genevestigator | P50275. |
| GermOnline | YOR058C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR007145. Microtubule-assoc_MAP65_ASE1. [Graphical view] |
| PANTHER | PTHR19321. MAP65_ASE1. 1 hit. |
| Pfam | PF03999. MAP65_ASE1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 976092. |
Entry information
| Entry name | ASE1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P50275 Secondary accession number(s): D6W2C1 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| SIMILARITY comments Index of protein domains and families |

Clusters with