P50266 (CYB5R_DROVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome b5-related protein

Gene names

Name:

Cyt-b5-r

Organism

Drosophila virilis (Fruit fly)

Taxonomic identifier

7244 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in muscle cell metabolism By similarity.
Sequence similarities	Belongs to the cytochrome b5 family. Contains 1 cytochrome b5 heme-binding domain.

Ontologies

Keywords
Ligand	Heme Iron Metal-binding
Gene Ontology (GO)
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 142	142	Cytochrome b5-related protein		PRO_0000166019
Regions
	Domain	16 – 100	85	Cytochrome b5 heme-binding
Sites
	Metal binding	59	1	Iron (heme axial ligand) By similarity
	Metal binding	82	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P50266 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 287EBEA44AE7652D	FASTA	142	16,707
	10 20 30 40 50 60 MVIETWKKSG IATKFPTYRN SAPVTVHSWQ KGKRQDVEAE GLWRIKDGIY DFTEFIDKHP 70 80 90 100 110 120 GGTFWIRETK GTDITEAFEA HHLTTAPEKM IAKYKVRDAY QRIYTLTLHE DGFYKTLKER 130 140 VREKLKTIDK RPKRKSDVSD DL

References

[1]	"Evolutionary divergence of the cytochrome b5 gene of Drosophila." Kula M.E., Allay E.R., Rozek C.E. J. Mol. Evol. 41:430-439(1995) [PubMed: 7563130] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U12418 Genomic DNA. Translation: AAA85492.1.
3D structure databases
ProteinModelPortal	P50266.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0013913. Dvir\Cyt-b5-r.
Phylogenomic databases
GeneTree	EMGT00050000017423.
InParanoid	P50266.
OrthoDB	EOG40K6F4.
Family and domain databases
InterPro	IPR001199. Cyt_B5. IPR018506. Cyt_B5_heme-BS. [Graphical view]
Gene3D	G3DSA:3.10.120.10. Cyt_B5. 1 hit.
Pfam	PF00173. Cyt-b5. 1 hit. [Graphical view]
PRINTS	PR00363. CYTOCHROMEB5.
SUPFAM	SSF55856. Cyt_B5. 1 hit.
PROSITE	PS00191. CYTOCHROME_B5_1. 1 hit. PS50255. CYTOCHROME_B5_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYB5R_DROVI

Accession

Primary (citable) accession number: P50266

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 16, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project