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Protein

Probable transcriptional regulatory protein STB4

Gene

STB4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Binds to SIN3.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi87 – 11327Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32725-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transcriptional regulatory protein STB4
Gene namesi
Name:STB4
Ordered Locus Names:YMR019W
ORF Names:YM9711.08
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR019W.
SGDiS000004621. STB4.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 949949Probable transcriptional regulatory protein STB4PRO_0000114980Add
BLAST

Proteomic databases

MaxQBiP50104.

PTM databases

iPTMnetiP50104.

Interactioni

Protein-protein interaction databases

BioGridi35190. 29 interactions.
DIPiDIP-2487N.
MINTiMINT-687866.

Structurei

3D structure databases

ProteinModelPortaliP50104.
SMRiP50104. Positions 85-116.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiP50104.
OMAiEWESFEL.
OrthoDBiEOG092C0DDW.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50104-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSINHEIYYI LVFEHRSVAI KLIIVVIVLL QFFLARSRQI DRTWAHTNRK
60 70 80 90 100
ERFREMTAIG NTDDALDTST AASKENGKGR LRVQKACELC KKRKVKCDGN
110 120 130 140 150
NPCLNCSKHQ KECRYDFKAT NRKRRRRQVA SAVRDVSKTY AETSESFPRD
160 170 180 190 200
LLSKSNIIIN APSDGVSSSA SNSPNPNSHY HHISSTLPFM SGRPNHTFHS
210 220 230 240 250
GSNLNGENNN NSFPEDHMAK LLLQLSSKLG NTTKESSIRT TRTNASDVNA
260 270 280 290 300
NPTVVNMKNS QEDCDTNHRS AICDSAEALH NNNINSKENK IINSQITNTV
310 320 330 340 350
NDHFESPWQT FSLDKYRFHR RYQNILPYYL GVSILKDLSP QTIEYAKLKR
360 370 380 390 400
PRVQNYGWNL SGGHYLKYKG DFRSQEKNIR HESKFFDFDD PVHLSLINKL
410 420 430 440 450
LRYYFDEINP VFSIIHEATF WQQYNNKFLR QGKQNNSSAN LFTSMLYLIL
460 470 480 490 500
STTLRFREGH LDGQKGQGTY SNTSLNITFE EKSILIKKPS IEENLFKYAY
510 520 530 540 550
LIINTLTFEW ESFELIQSWL LITFYFRTCY RQTACWNALS QAVNMCNGMS
560 570 580 590 600
LYLNKFPEIH STYDESKAWH CFWCCFIMDK LISFQMGRFY QLSLPASEMC
610 620 630 640 650
EQMNLVKSKK FLQEEDDWFH EETFQMLDLS IIVTQFLKRD AQDLNLNETV
660 670 680 690 700
QLRSQLGQWY DTFIVGSQTN AYDDNYRYFY QVQPFMTYLD IRLTFEVRQL
710 720 730 740 750
FCLIAPSSTA NNKSLEYVVD TELLISHCQM AIENLAEITR SNLFFVPWWL
760 770 780 790 800
NLSQLFTVNL ICIIYLHAGI AVTQNKAIMQ SCQEIWRTLE CSKPKNRPSM
810 820 830 840 850
LPECLWCLKM LNHMFCIRLR DSALQLEATL GTDHGDDTPN RNKFEQFKKV
860 870 880 890 900
GDNDADVEVD AGEREENADE RQENPHNNSK RVPLATRSHN TTNFDGSIAI
910 920 930 940
SPESAVANLG TDTGLPSDVL DTVSKIGNSP NVFDDDLFSN LLWFDQNFA
Length:949
Mass (Da):109,825
Last modified:October 1, 1996 - v1
Checksum:iED3BF5E26F596CF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49211 Genomic DNA. Translation: CAA89121.1.
BK006946 Genomic DNA. Translation: DAA09917.1.
PIRiS54020.
RefSeqiNP_013732.1. NM_001182515.1.

Genome annotation databases

EnsemblFungiiYMR019W; YMR019W; YMR019W.
GeneIDi855033.
KEGGisce:YMR019W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49211 Genomic DNA. Translation: CAA89121.1.
BK006946 Genomic DNA. Translation: DAA09917.1.
PIRiS54020.
RefSeqiNP_013732.1. NM_001182515.1.

3D structure databases

ProteinModelPortaliP50104.
SMRiP50104. Positions 85-116.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35190. 29 interactions.
DIPiDIP-2487N.
MINTiMINT-687866.

PTM databases

iPTMnetiP50104.

Proteomic databases

MaxQBiP50104.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR019W; YMR019W; YMR019W.
GeneIDi855033.
KEGGisce:YMR019W.

Organism-specific databases

EuPathDBiFungiDB:YMR019W.
SGDiS000004621. STB4.

Phylogenomic databases

InParanoidiP50104.
OMAiEWESFEL.
OrthoDBiEOG092C0DDW.

Enzyme and pathway databases

BioCyciYEAST:G3O-32725-MONOMER.

Miscellaneous databases

PROiP50104.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSTB4_YEAST
AccessioniPrimary (citable) accession number: P50104
Secondary accession number(s): D6VZJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 7, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 98 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.