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P49988 (RP54_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
RNA polymerase sigma-54 factor
Gene names
Name:rpoN
Ordered Locus Names:PA4462
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

Sequence similarities

Belongs to the sigma-54 factor family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 497497RNA polymerase sigma-54 factor
PRO_0000205534

Regions

DNA binding386 – 40520H-T-H motif Potential
Motif474 – 4829RPON box
Compositional bias11 – 3525Gln-rich

Experimental info

Sequence conflict3521S → T in AAA19793. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P49988 [UniParc].

Last modified December 8, 2000. Version 2.
Checksum: CE1994F03FD58405

FASTA49756,054
        10         20         30         40         50         60 
MKPSLVLKMG QQLTMTPQLQ QAIRLLQLST LDLQQEIQEA LESNPMLERQ EDGDDFDNSD 

        70         80         90        100        110        120 
PLADGAEQAA SAPQESPLQE SATPSVESLD DDQWSERIPS ELPVDTAWED IYQTSASSLP 

       130        140        150        160        170        180 
SNDDDEWDFT ARTSSGESLH SHLLWQVNLA PMSDTDRMIA VTIIDSINND GYLEESLEEI 

       190        200        210        220        230        240 
LAAIDPELDV ELDEVEVVLR RIQQLEPAGI GARNLRECLL LQLRQLPSTT PWLNEALRLV 

       250        260        270        280        290        300 
SDYLDLLGGR DYSQLMRRMK LKEDELRQVI ELIQCLHPRP GSQIESSEAE YIVPDVIVRK 

       310        320        330        340        350        360 
DNERWLVELN QEAMPRLRVN ATYAGMVRRA DSSADNTFMR NQLQEARWFI KSLQSRNETL 

       370        380        390        400        410        420 
MKVATQIVEH QRGFLDYGEE AMKPLVLHDI AEAVGMHEST ISRVTTQKYM HTPRGIFELK 

       430        440        450        460        470        480 
YFFSSHVSTA EGGECSSTAI RAIIKKLVAA ENAKKPLSDS KIAGLLEAQG IQVARRTVAK 

       490 
YRESLGIAPS SERKRLV 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of the rpoN gene and characterization of two downstream open reading frames in Pseudomonas aeruginosa."
Jin S., Ishimoto K., Lory S.
J. Bacteriol. 176:1316-1322(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: PAK.
[2]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L26916 Unassigned DNA. Translation: AAA19793.1.
AE004091 Genomic DNA. Translation: AAG07850.1.
PIRA53373.
F83087.
RefSeqNP_253152.1. NC_002516.2.

3D structure databases

ProteinModelPortalP49988.
SMRP49988. Positions 417-494.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-8407298.
STRING208964.PA4462.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG07850; AAG07850; PA4462.
GeneID881022.
KEGGpae:PA4462.
PATRIC19843651. VBIPseAer58763_4672.

Organism-specific databases

PseudoCAPPA4462.

Phylogenomic databases

eggNOGCOG1508.
HOGENOMHOG000071905.
KOK03092.
OMATQKFMHT.
OrthoDBEOG60CWN7.
PhylomeDBP49988.

Family and domain databases

InterProIPR000394. RNA_pol_sigma_54.
IPR007046. RNA_pol_sigma_54_core-bd.
IPR007634. RNA_pol_sigma_54_DNA-bd.
[Graphical view]
PfamPF00309. Sigma54_AID. 1 hit.
PF04963. Sigma54_CBD. 1 hit.
PF04552. Sigma54_DBD. 1 hit.
[Graphical view]
PIRSFPIRSF000774. RpoN. 1 hit.
PRINTSPR00045. SIGMA54FCT.
TIGRFAMsTIGR02395. rpoN_sigma. 1 hit.
PROSITEPS00717. SIGMA54_1. 1 hit.
PS00718. SIGMA54_2. 1 hit.
PS50044. SIGMA54_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRP54_PSEAE
AccessionPrimary (citable) accession number: P49988
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 8, 2000
Last modified: July 9, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families