Reviewed, UniProtKB/Swiss-Prot P49942 (XYNA_BACOV)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase A
      Short name=Xylanase A
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:

xylI

Organism

Bacteroides ovatus

Taxonomic identifier

28116 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Induction	By xylan.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 376	352	Endo-1,4-beta-xylanase A		PRO_0000007966
Sites
	Active site	160	1	Proton donor By similarity
	Active site	265	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	P49942-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 40C3B36E2DAA3499	FASTA	376	42,980
	10 20 30 40 50 60 MKLKRIILLL LTVMFSFSYG EVFAKDGSSL KKALKNKFLI GVSVNTHQSS GKDVAAVEIV 70 80 90 100 110 120 KKNFNSIVAE NCMKSSVIHP KENKYNFAQA DEFVSFGESN QMAIIGHCLI WHSQLAPWFC 130 140 150 160 170 180 VDKDGNNVSP EVLKKRMKDH ITTIVKRYKG RIKGWDVVNE AIEDNGAYRK TKFYEILGEE 190 200 210 220 230 240 YIPLAFQYAH EADPDAELYY NDYSMAQPGR REAVVKMVND LKKRGIRIDA IGMQGHIGMD 250 260 270 280 290 300 YPKISEFEKS MLAFAGTGVK IMITELDLTV IPSPNPNVGA EVSASFEYKK EMNPYPDGLP 310 320 330 340 350 360 EEVSKAWTER MNDFFRLFLK HHNLITRVTL WGVADQNSWR NDWPMRGRTD YPLLFDRNYQ 370 PKPVVGLIIK EAEKTK

References

[1]	"Nucleotide sequences of xylan-inducible xylanase and xylosidase/arabinosidase genes from Bacteroides ovatus V975." Whitehead T.R. Biochim. Biophys. Acta 1244:239-241(1995) [PubMed: 7766665] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: V975.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U04957 Genomic DNA. Translation: AAB08023.1.
PIR	S55892.
3D structure databases
HSSP	HSSP built from PDB template 1HIZ based on UniProtKB P40943.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 97613.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_BACOV

Accession

Primary (citable) accession number: P49942

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	June 16, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)