##gff-version 3
P49914	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:22814378;Dbxref=PMID:19413330,PMID:22814378	
P49914	UniProtKB	Chain	2	203	.	.	.	ID=PRO_0000200275;Note=5-formyltetrahydrofolate cyclo-ligase	
P49914	UniProtKB	Binding site	10	14	.	.	.	.	
P49914	UniProtKB	Binding site	14	14	.	.	.	.	
P49914	UniProtKB	Binding site	56	56	.	.	.	.	
P49914	UniProtKB	Binding site	61	61	.	.	.	.	
P49914	UniProtKB	Binding site	145	153	.	.	.	.	
P49914	UniProtKB	Binding site	148	152	.	.	.	.	
P49914	UniProtKB	Binding site	154	154	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P49914	UniProtKB	Binding site	189	189	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P49914	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:22814378;Dbxref=PMID:19413330,PMID:22814378	
P49914	UniProtKB	Alternative sequence	1	39	.	.	.	ID=VSP_046863;Note=In isoform 2. MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQK->MARSRLTATSVSQVQ;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
P49914	UniProtKB	Natural variant	36	36	.	.	.	ID=VAR_082088;Note=In NEDMEHM. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30031689;Dbxref=dbSNP:rs1349638340,PMID:30031689	
P49914	UniProtKB	Natural variant	145	145	.	.	.	ID=VAR_082089;Note=In NEDMEHM. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30031689;Dbxref=dbSNP:rs753635972,PMID:30031689	
P49914	UniProtKB	Natural variant	162	203	.	.	.	ID=VAR_082090;Note=In NEDMEHM. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30031689;Dbxref=PMID:30031689	
P49914	UniProtKB	Natural variant	202	202	.	.	.	ID=VAR_034115;Note=T->A;Dbxref=dbSNP:rs8923	
P49914	UniProtKB	Mutagenesis	10	10	.	.	.	Note=Reduces activity by 93%25. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19738041;Dbxref=PMID:19738041	
P49914	UniProtKB	Mutagenesis	14	14	.	.	.	Note=Reduces activity by 87%25. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19738041;Dbxref=PMID:19738041	
P49914	UniProtKB	Mutagenesis	61	61	.	.	.	Note=Reduces activity by 94%25. E->A	
P49914	UniProtKB	Mutagenesis	145	145	.	.	.	Note=Reduces activity by 98%25. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19738041;Dbxref=PMID:19738041	
P49914	UniProtKB	Mutagenesis	153	153	.	.	.	Note=Reduces activity by 97%25. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19738041;Dbxref=PMID:19738041	
P49914	UniProtKB	Mutagenesis	154	154	.	.	.	Note=Reduces activity by 99%25. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19738041;Dbxref=PMID:19738041	
P49914	UniProtKB	Sequence conflict	177	177	.	.	.	Note=E->D;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P49914	UniProtKB	Sequence conflict	203	203	.	.	.	Note=A->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P49914	UniProtKB	Helix	2	22	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	26	41	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	44	48	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	50	53	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	65	73	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	77	84	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Turn	85	88	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	89	95	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	98	101	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	123	125	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	130	134	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	137	139	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	148	150	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	152	160	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Turn	161	163	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	169	173	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Helix	176	178	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3	
P49914	UniProtKB	Beta strand	179	181	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HXT	
P49914	UniProtKB	Beta strand	193	196	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HY3