SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P49746

- TSP3_HUMAN

UniProt

P49746 - TSP3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Thrombospondin-3
Gene
THBS3, TSP3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.

GO - Molecular functioni

  1. calcium ion binding Source: UniProtKB
  2. heparin binding Source: MGI
Complete GO annotation...

GO - Biological processi

  1. bone trabecula formation Source: Ensembl
  2. cell-matrix adhesion Source: UniProtKB
  3. growth plate cartilage development Source: Ensembl
  4. ossification involved in bone maturation Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium

Enzyme and pathway databases

ReactomeiREACT_16888. Signaling by PDGF.

Names & Taxonomyi

Protein namesi
Recommended name:
Thrombospondin-3
Gene namesi
Name:THBS3
Synonyms:TSP3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:11787. THBS3.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: Reactome
  2. perinuclear region of cytoplasm Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36499.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed prediction
Add
BLAST
Chaini23 – 956934Thrombospondin-3
PRO_0000035849Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi266 – 266Interchain Inferred
Disulfide bondi269 – 269Interchain Inferred
Disulfide bondi278 ↔ 289 By similarity
Disulfide bondi283 ↔ 300 By similarity
Disulfide bondi303 ↔ 314 By similarity
Glycosylationi310 – 3101N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi320 ↔ 332 By similarity
Disulfide bondi326 ↔ 341 By similarity
Disulfide bondi344 ↔ 368 By similarity
Disulfide bondi374 ↔ 388 By similarity
Disulfide bondi382 ↔ 397 By similarity
Disulfide bondi400 ↔ 412 By similarity
Glycosylationi407 – 4071N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi418 ↔ 432 By similarity
Disulfide bondi426 ↔ 442 By similarity
Disulfide bondi444 ↔ 455 By similarity
Disulfide bondi471 ↔ 478 By similarity
Disulfide bondi483 ↔ 503 By similarity
Disulfide bondi519 ↔ 539 By similarity
Disulfide bondi542 ↔ 562 By similarity
Disulfide bondi578 ↔ 598 By similarity
Disulfide bondi601 ↔ 621 By similarity
Disulfide bondi639 ↔ 659 By similarity
Glycosylationi644 – 6441N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi679 ↔ 699 By similarity
Disulfide bondi715 ↔ 936 By similarity
Glycosylationi937 – 9371N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP49746.
PaxDbiP49746.
PRIDEiP49746.

PTM databases

PhosphoSiteiP49746.

Expressioni

Gene expression databases

ArrayExpressiP49746.
BgeeiP49746.
CleanExiHS_THBS3.
GenevestigatoriP49746.

Organism-specific databases

HPAiHPA006293.

Interactioni

Subunit structurei

Oligomer; disulfide-linked.

Protein-protein interaction databases

BioGridi112917. 1 interaction.
STRINGi9606.ENSP00000357362.

Structurei

3D structure databases

ProteinModelPortaliP49746.
SMRiP49746. Positions 52-148, 278-945.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 193171Laminin G-like
Add
BLAST
Domaini316 – 35439EGF-like 1; calcium-binding Reviewed prediction
Add
BLAST
Domaini370 – 41041EGF-like 2; calcium-binding Reviewed prediction
Add
BLAST
Domaini414 – 45643EGF-like 3
Add
BLAST
Repeati457 – 49135TSP type-3 1
Add
BLAST
Repeati492 – 52736TSP type-3 2
Add
BLAST
Repeati528 – 55023TSP type-3 3
Add
BLAST
Repeati551 – 58636TSP type-3 4
Add
BLAST
Repeati587 – 60923TSP type-3 5
Add
BLAST
Repeati610 – 64738TSP type-3 6
Add
BLAST
Repeati648 – 68740TSP type-3 7
Add
BLAST
Repeati688 – 72336TSP type-3 8
Add
BLAST
Domaini727 – 941215TSP C-terminal
Add
BLAST

Sequence similaritiesi

Belongs to the thrombospondin family.
Contains 3 EGF-like domains.
Contains 8 TSP type-3 repeats.

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000007542.
HOVERGENiHBG000636.
InParanoidiP49746.
KOiK04659.
OMAiWRDKTSY.
OrthoDBiEOG76QFGD.
PhylomeDBiP49746.
TreeFamiTF324917.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
4.10.1080.10. 2 hits.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
IPR001791. Laminin_G.
IPR024665. Thbs/COMP_coiled-coil.
IPR028507. Thrombospondin-3.
IPR003367. Thrombospondin_3-like_rpt.
IPR017897. Thrombospondin_3_rpt.
IPR008859. Thrombospondin_C.
IPR028974. TSP_type-3_rpt.
[Graphical view]
PANTHERiPTHR10199:SF5. PTHR10199:SF5. 1 hit.
PfamiPF11598. COMP. 1 hit.
PF07645. EGF_CA. 2 hits.
PF02412. TSP_3. 6 hits.
PF05735. TSP_C. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 2 hits.
SM00179. EGF_CA. 2 hits.
SM00210. TSPN. 1 hit.
[Graphical view]
SUPFAMiSSF103647. SSF103647. 3 hits.
SSF49899. SSF49899. 2 hits.
PROSITEiPS01186. EGF_2. 1 hit.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 2 hits.
PS51234. TSP3. 8 hits.
PS51236. TSP_CTER. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P49746-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

METQELRGAL ALLLLCFFTS ASQDLQVIDL LTVGESRQMV AVAEKIRTAL    50
LTAGDIYLLS TFRLPPKQGG VLFGLYSRQD NTRWLEASVV GKINKVLVRY 100
QREDGKVHAV NLQQAGLADG RTHTVLLRLR GPSRPSPALH LYVDCKLGDQ 150
HAGLPALAPI PPAEVDGLEI RTGQKAYLRM QGFVESMKII LGGSMARVGA 200
LSECPFQGDE SIHSAVTNAL HSILGEQTKA LVTQLTLFNQ ILVELRDDIR 250
DQVKEMSLIR NTIMECQVCG FHEQRSHCSP NPCFRGVDCM EVYEYPGYRC 300
GPCPPGLQGN GTHCSDINEC AHADPCFPGS SCINTMPGFH CEACPRGYKG 350
TQVSGVGIDY ARASKQVCND IDECNDGNNG GCDPNSICTN TVGSFKCGPC 400
RLGFLGNQSQ GCLPARTCHS PAHSPCHIHA HCLFERNGAV SCQCNVGWAG 450
NGNVCGTDTD IDGYPDQALP CMDNNKHCKQ DNCLLTPNSG QEDADNDGVG 500
DQCDDDADGD GIKNVEDNCR LFPNKDQQNS DTDSFGDACD NCPNVPNNDQ 550
KDTDGNGEGD ACDNDVDGDG IPNGLDNCPK VPNPLQTDRD EDGVGDACDS 600
CPEMSNPTQT DADSDLVGDV CDTNEDSDGD GHQDTKDNCP QLPNSSQLDS 650
DNDGLGDECD GDDDNDGIPD YVPPGPDNCR LVPNPNQKDS DGNGVGDVCE 700
DDFDNDAVVD PLDVCPESAE VTLTDFRAYQ TVVLDPEGDA QIDPNWVVLN 750
QGMEIVQTMN SDPGLAVGYT AFNGVDFEGT FHVNTVTDDD YAGFLFSYQD 800
SGRFYVVMWK QTEQTYWQAT PFRAVAQPGL QLKAVTSVSG PGEHLRNALW 850
HTGHTPDQVR LLWTDPRNVG WRDKTSYRWQ LLHRPQVGYI RVKLYEGPQL 900
VADSGVIIDT SMRGGRLGVF CFSQENIIWS NLQYRCNDTV PEDFEPFRRQ 950
LLQGRV 956
Length:956
Mass (Da):104,201
Last modified:October 1, 1996 - v1
Checksum:iAE9B136DF0FFE5B8
GO
Isoform 2 (identifier: P49746-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     96-215: Missing.

Show »
Length:836
Mass (Da):91,297
Checksum:i8D7AA90E4B21CA96
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti279 – 2791S → G.
Corresponds to variant rs35154152 [ dbSNP | Ensembl ].
VAR_052658
Natural varianti955 – 9551R → G in a breast cancer sample; somatic mutation. 1 Publication
VAR_035808

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei96 – 215120Missing in isoform 2.
VSP_045328Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L38969 mRNA. Translation: AAC41762.1.
AL713999 Genomic DNA. Translation: CAI95084.1.
AF023268 Genomic DNA. Translation: AAC51818.1.
AK298592 mRNA. Translation: BAG60782.1.
CH471121 Genomic DNA. Translation: EAW53110.1.
BC018786 mRNA. Translation: AAH18786.1.
CCDSiCCDS1099.1. [P49746-1]
CCDS58034.1. [P49746-2]
PIRiA57121.
RefSeqiNP_001239536.1. NM_001252607.1.
NP_001239537.1. NM_001252608.1. [P49746-2]
NP_009043.1. NM_007112.4. [P49746-1]
UniGeneiHs.169875.
Hs.658188.

Genome annotation databases

EnsembliENST00000368378; ENSP00000357362; ENSG00000169231. [P49746-1]
ENST00000457183; ENSP00000392207; ENSG00000169231. [P49746-2]
GeneIDi7059.
KEGGihsa:7059.
UCSCiuc001fix.3. human. [P49746-1]
uc010pfu.2. human.

Polymorphism databases

DMDMi1717814.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L38969 mRNA. Translation: AAC41762.1 .
AL713999 Genomic DNA. Translation: CAI95084.1 .
AF023268 Genomic DNA. Translation: AAC51818.1 .
AK298592 mRNA. Translation: BAG60782.1 .
CH471121 Genomic DNA. Translation: EAW53110.1 .
BC018786 mRNA. Translation: AAH18786.1 .
CCDSi CCDS1099.1. [P49746-1 ]
CCDS58034.1. [P49746-2 ]
PIRi A57121.
RefSeqi NP_001239536.1. NM_001252607.1.
NP_001239537.1. NM_001252608.1. [P49746-2 ]
NP_009043.1. NM_007112.4. [P49746-1 ]
UniGenei Hs.169875.
Hs.658188.

3D structure databases

ProteinModelPortali P49746.
SMRi P49746. Positions 52-148, 278-945.
ModBasei Search...

Protein-protein interaction databases

BioGridi 112917. 1 interaction.
STRINGi 9606.ENSP00000357362.

PTM databases

PhosphoSitei P49746.

Polymorphism databases

DMDMi 1717814.

Proteomic databases

MaxQBi P49746.
PaxDbi P49746.
PRIDEi P49746.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000368378 ; ENSP00000357362 ; ENSG00000169231 . [P49746-1 ]
ENST00000457183 ; ENSP00000392207 ; ENSG00000169231 . [P49746-2 ]
GeneIDi 7059.
KEGGi hsa:7059.
UCSCi uc001fix.3. human. [P49746-1 ]
uc010pfu.2. human.

Organism-specific databases

CTDi 7059.
GeneCardsi GC01M155165.
H-InvDB HIX0029532.
HGNCi HGNC:11787. THBS3.
HPAi HPA006293.
MIMi 188062. gene.
neXtProti NX_P49746.
PharmGKBi PA36499.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000007542.
HOVERGENi HBG000636.
InParanoidi P49746.
KOi K04659.
OMAi WRDKTSY.
OrthoDBi EOG76QFGD.
PhylomeDBi P49746.
TreeFami TF324917.

Enzyme and pathway databases

Reactomei REACT_16888. Signaling by PDGF.

Miscellaneous databases

ChiTaRSi THBS3. human.
GeneWikii THBS3.
GenomeRNAii 7059.
NextBioi 27605.
PROi P49746.
SOURCEi Search...

Gene expression databases

ArrayExpressi P49746.
Bgeei P49746.
CleanExi HS_THBS3.
Genevestigatori P49746.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
4.10.1080.10. 2 hits.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
IPR001791. Laminin_G.
IPR024665. Thbs/COMP_coiled-coil.
IPR028507. Thrombospondin-3.
IPR003367. Thrombospondin_3-like_rpt.
IPR017897. Thrombospondin_3_rpt.
IPR008859. Thrombospondin_C.
IPR028974. TSP_type-3_rpt.
[Graphical view ]
PANTHERi PTHR10199:SF5. PTHR10199:SF5. 1 hit.
Pfami PF11598. COMP. 1 hit.
PF07645. EGF_CA. 2 hits.
PF02412. TSP_3. 6 hits.
PF05735. TSP_C. 1 hit.
[Graphical view ]
SMARTi SM00181. EGF. 2 hits.
SM00179. EGF_CA. 2 hits.
SM00210. TSPN. 1 hit.
[Graphical view ]
SUPFAMi SSF103647. SSF103647. 3 hits.
SSF49899. SSF49899. 2 hits.
PROSITEi PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 2 hits.
PS51234. TSP3. 8 hits.
PS51236. TSP_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structure and organization of the human thrombospondin 3 gene (THBS3)."
    Adolph K.W., Long G.L., Winfield S., Ginns E.I., Bornstein P.
    Genomics 27:329-336(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Lung.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
  3. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease."
    Winfield S.L., Tayebi N., Martin B.M., Ginns E.I., Sidransky E.
    Genome Res. 7:1020-1026(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-736.
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 365-956.
    Tissue: Retina.
  7. Cited for: VARIANT [LARGE SCALE ANALYSIS] GLY-955.

Entry informationi

Entry nameiTSP3_HUMAN
AccessioniPrimary (citable) accession number: P49746
Secondary accession number(s): B1AVR8, B4DQ20, Q8WV34
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 3, 2014
This is version 139 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi