Reviewed, UniProtKB/Swiss-Prot P49726 (SPE1_SOLLC)

Names and origin

Protein names	Recommended name:     Arginine decarboxylase       Short name=ARGDC       Short name=ADC     EC=4.1.1.19
Organism	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifier	4081 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2.
Cofactor	Pyridoxal phosphate. Magnesium.
Pathway	Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis Spermidine biosynthesis
Ligand	Magnesium Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 502	502	Arginine decarboxylase		PRO_0000149951
Regions
	Region	226 – 236	11	Substrate-binding By similarity
Amino acid modifications
	Modified residue	42	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P49726-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 628D32D4560E9A1F	FASTA	502	54,581
	10 20 30 40 50 60 MPLVVRFPDV LKNRLETLQS AFDMAINSQG YEAHYQGVYP VKCNQDRFVV EDIVKFGSPY 70 80 90 100 110 120 RFGLEAGSKP ELLLAMNCLS KGSADALLVC NGFKDTEYIS LALVARKLLL NSVIVLEQEE 130 140 150 160 170 180 ELDLVIDISR KMSVRPVIGL RAKLRTKHSG HFGSTSGEKG KFGLTTTQIL RVVKKLDESG 190 200 210 220 230 240 MLDCLQLLHF HIGSQIPTTE LLADGVGEAT QIYSELVRLG AGMKFIDIGG GLGIDYDGSK 250 260 270 280 290 300 SSNSDVSVCY SIEEYASAVV QAVLYVCDRK GGKHPVICSE SGRAIVSHHS ILIFEAVSAS 310 320 330 340 350 360 TSHVSTQPSS GGLQSLVETL NEDARADYRN LSAAAVRGEY DTCLIYSDQL KQRCVEQFKD 370 380 390 400 410 420 GSLDIEQLAA VDSICDWVSK AIGVADPVRT YHVNLSVFTS IPDFWGFSQL FPIVPIHRLD 430 440 450 460 470 480 EKPTMRGILS DLTCDSDGKV DKFIGGESSL PLHEIGSGDG GRYYLGMFLG GAYEEALGGL 490 500 HNLFGGPSVV RVMQSDSPHS FA

References

[1]	"Cloning of tomato (Lycopersicon esculentum Mill.) arginine decarboxylase gene and its expression during fruit ripening." Rastogi R., Dulson J., Rothstein S.J. Plant Physiol. 103:829-834(1993) [PubMed: 8022938] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Pericarp.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L16582 mRNA. Translation: AAA61347.1.
PIR	JQ2341.
UniGene	Les.19532
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.19. 281054.
Family and domain databases
InterPro	IPR002985. Arg_decrbxlase. IPR000183. De-COase2. [Graphical view]
PANTHER	PTHR11482:SF3. Arg_decrbxlase. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PRINTS	PR01180. ARGDCRBXLASE. PR01179. ODADCRBXLASE.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPE1_SOLLC

Accession

Primary (citable) accession number: P49726

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	July 28, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)