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Protein

Stage II sporulation protein E

Gene

spoIIE

Organism
Bacillus megaterium
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphatase
Biological processSporulation

Names & Taxonomyi

Protein namesi
Recommended name:
Stage II sporulation protein E (EC:3.1.3.16)
Gene namesi
Name:spoIIE
OrganismiBacillus megaterium
Taxonomic identifieri1404 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Subcellular locationi

P49600:

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 57HelicalSequence analysisAdd BLAST18
Transmembranei70 – 86HelicalSequence analysisAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000057793‹1 – 585Stage II sporulation protein EAdd BLAST›585

Structurei

3D structure databases

ProteinModelPortaliP49600.
SMRiP49600.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini355 – 565PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST211

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105G3A. Bacteria.
COG2208. LUCA.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR036457. PPM-type_dom_sf.
IPR001932. PPM-type_phosphatase_dom.
IPR014221. Spore_II_E.
PfamiView protein in Pfam
PF07228. SpoIIE. 1 hit.
SMARTiView protein in SMART
SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 1 hit.
TIGRFAMsiTIGR02865. spore_II_E. 1 hit.
PROSITEiView protein in PROSITE
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

P49600-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TVGVVTGLIL SFANVSSLYE MSLLAFSGLL GGLLKDGKKL GARLGLVVGS
60 70 80 90 100
LLIGLYAQAD QGLTTNLYES LTAVVLFLLT PSFVLKNLSK LVPGTSENML
110 120 130 140 150
EQQQYVRKIR DVTANRVEQF SNVFQALSKS FTQNGFYDEK PSADKEVDYF
160 170 180 190 200
LSSVTERTCQ FCFKKEQCWA QQFDTTYEYM KEIMLEVDNG TLEQNPRLIR
210 220 230 240 250
EMDKHCVKSK KVIDVIEHEL TYFKANQHLK AQIQESRRIV AEQLHGVSEV
260 270 280 290 300
MGNFAKEIKR ERENLNVQEE QILEALRNFG MEINQIEIYS LEPGNVDIEM
310 320 330 340 350
WVPYCHGRGE CEKIIAPMLT DILGESIVVK NEECAKYPQG YCHVSFGCTK
360 370 380 390 400
AYVVDTGVAH AAKGGGFVSG DSYSMIELNA GKYALAISDG MGNGERAHYE
410 420 430 440 450
SSETLQLLKQ ILQTGIEETI AIKSINSILS LRTNDEIFST LDLAMIDLQD
460 470 480 490 500
ANVNFLKIGS TPSFIKRGDK VIKIQASNLP MGIIEEFEVD VVNEQMKAED
510 520 530 540 550
LLIMMSDGVF EGPKHVENYE MWMKRKIGEL QTNDPQEIAD LIMEEVIRTK
560 570 580
VGLIEDDMTV VVAKLQHNTP KWSSIPSYAY RNLAQ
Length:585
Mass (Da):65,690
Last modified:February 1, 1996 - v1
Checksum:i90E9ACF1D3E21D01
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U26836 Genomic DNA. Translation: AAB58072.1.
PIRiS71018.
S73325.

Similar proteinsi

Entry informationi

Entry nameiSP2E_BACME
AccessioniPrimary (citable) accession number: P49600
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 25, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program