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P49595 (PP2C1_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C F42G9.1

Short name=PP2C
EC=3.1.3.16
Gene names
ORF Names:F42G9.1
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 491491Probable protein phosphatase 2C F42G9.1
PRO_0000057762

Sites

Metal binding571Manganese 1 By similarity
Metal binding571Manganese 2 By similarity
Metal binding581Manganese 1; via carbonyl oxygen By similarity
Metal binding4281Manganese 2 By similarity
Metal binding4771Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P49595 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: F110D12E343953D6

FASTA49153,142
        10         20         30         40         50         60 
MGAYLNKPII EKEKEEGSGN GLSYACTTMQ GWRVNQEDAH NCVVDLHTDW HMFGVYDGHG 

        70         80         90        100        110        120 
GTEVSKFTSA KLPDFLKERK FWEADDVAEC LQKAFVDFDD FIRAEESMKE LKDIGDEGKP 

       130        140        150        160        170        180 
KKAGGEADSE DEADRIDTIE EASVPLAELL KRYGGAGVGK SLLSAFLAKG DVSDDSEDED 

       190        200        210        220        230        240 
EDEEEAEEQD DTEEKKENED ASAEVVIENA EDKEEEEGSP KKKGQKRCQK SPIQSEAKKS 

       250        260        270        280        290        300 
KSETDAETAP SSSSGVDGVA TEEEDEDDSD KEFVADEEED DEDAEDEQSD EEMVDGSLAP 

       310        320        330        340        350        360 
LLLGSGGAEV PGEDSGTTAC VCLVGKDKVI VANAGDSRAV LCRNGKAVDL SVDHKPEDEV 

       370        380        390        400        410        420 
ETNRIHAAGG QIEDGRVNGG LNLSRAFGDH AYKKNQELGL KEQMITALPD VKIEALTPED 

       430        440        450        460        470        480 
EFIVVACDGI WNSMESQQVV DFVRDLLAKG SSCAEVCDAL CDACLADSTD GDGTGCDNMT 

       490 
VICTTFDRKS K 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO080196 Genomic DNA. Translation: CCD61882.1.
PIRT16354.
RefSeqNP_741086.1. NM_171075.4.
UniGeneCel.7334.

3D structure databases

ProteinModelPortalP49595.
SMRP49595. Positions 4-103, 305-486.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP49595. 2 interactions.
STRING6239.F42G9.1a.

Proteomic databases

PaxDbP49595.
PRIDEP49595.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF42G9.1a; F42G9.1a; WBGene00018362.
GeneID175233.
KEGGcel:CELE_F42G9.1.
UCSCF42G9.1a. c. elegans.

Organism-specific databases

CTD175233.
WormBaseF42G9.1a; CE07231; WBGene00018362.

Phylogenomic databases

eggNOGCOG0631.
GeneTreeENSGT00730000110861.
HOGENOMHOG000233896.
InParanoidP49595.
KOK17499.
OMAIWNSMES.
PhylomeDBP49595.

Gene expression databases

ArrayExpressP49595.

Family and domain databases

Gene3D3.60.40.10. 2 hits.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 2 hits.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio887334.
PROP49595.

Entry information

Entry namePP2C1_CAEEL
AccessionPrimary (citable) accession number: P49595
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase