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Protein

Probable protein phosphatase 2C F42G9.1

Gene

F42G9.1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi57Manganese 1By similarity1
Metal bindingi57Manganese 2By similarity1
Metal bindingi58Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi428Manganese 2By similarity1
Metal bindingi477Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C F42G9.1 (EC:3.1.3.16)
Short name:
PP2C
Gene namesi
ORF Names:F42G9.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF42G9.1a ; CE07231 ; WBGene00018362

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000577621 – 491Probable protein phosphatase 2C F42G9.1Add BLAST491

Proteomic databases

EPDiP49595
PaxDbiP49595
PeptideAtlasiP49595
PRIDEiP49595

PTM databases

iPTMnetiP49595

Expressioni

Gene expression databases

BgeeiWBGene00018362
ExpressionAtlasiP49595 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiP49595, 2 interactors
STRINGi6239.F42G9.1a.1

Structurei

3D structure databases

ProteinModelPortaliP49595
SMRiP49595
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 486PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST464

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0699 Eukaryota
COG0631 LUCA
GeneTreeiENSGT00910000144272
HOGENOMiHOG000233896
InParanoidiP49595
KOiK17499
OMAiYCALYLP
OrthoDBiEOG091G0D0W
PhylomeDBiP49595

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 2 hits
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 2 hits
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

P49595-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYLNKPII EKEKEEGSGN GLSYACTTMQ GWRVNQEDAH NCVVDLHTDW
60 70 80 90 100
HMFGVYDGHG GTEVSKFTSA KLPDFLKERK FWEADDVAEC LQKAFVDFDD
110 120 130 140 150
FIRAEESMKE LKDIGDEGKP KKAGGEADSE DEADRIDTIE EASVPLAELL
160 170 180 190 200
KRYGGAGVGK SLLSAFLAKG DVSDDSEDED EDEEEAEEQD DTEEKKENED
210 220 230 240 250
ASAEVVIENA EDKEEEEGSP KKKGQKRCQK SPIQSEAKKS KSETDAETAP
260 270 280 290 300
SSSSGVDGVA TEEEDEDDSD KEFVADEEED DEDAEDEQSD EEMVDGSLAP
310 320 330 340 350
LLLGSGGAEV PGEDSGTTAC VCLVGKDKVI VANAGDSRAV LCRNGKAVDL
360 370 380 390 400
SVDHKPEDEV ETNRIHAAGG QIEDGRVNGG LNLSRAFGDH AYKKNQELGL
410 420 430 440 450
KEQMITALPD VKIEALTPED EFIVVACDGI WNSMESQQVV DFVRDLLAKG
460 470 480 490
SSCAEVCDAL CDACLADSTD GDGTGCDNMT VICTTFDRKS K
Length:491
Mass (Da):53,142
Last modified:October 1, 1996 - v2
Checksum:iF110D12E343953D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080196 Genomic DNA Translation: CCD61882.1
PIRiT16354
RefSeqiNP_741086.1, NM_171075.4
UniGeneiCel.7334

Genome annotation databases

EnsemblMetazoaiF42G9.1a; F42G9.1a; WBGene00018362
GeneIDi175233
KEGGicel:CELE_F42G9.1
UCSCiF42G9.1a c. elegans

Similar proteinsi

Entry informationi

Entry nameiPP2C1_CAEEL
AccessioniPrimary (citable) accession number: P49595
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health