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Protein

Chalcone synthase 17

Gene

CHS17

Organism
Phaseolus vulgaris (Kidney bean) (French bean)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi: flavonoid biosynthesis

This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei164PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processFlavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 17 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 17
Gene namesi
Name:CHS17
OrganismiPhaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifieri3885 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaePhaseolus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002160391 – 389Chalcone synthase 17Add BLAST389

Expressioni

Inductioni

By irradiation, elicitor, infection or wounding.

Structurei

3D structure databases

ProteinModelPortaliP49440
SMRiP49440
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10, 2 hits
InterProiView protein in InterPro
IPR012328 Chalcone/stilbene_synth_C
IPR018088 Chalcone/stilbene_synthase_AS
IPR001099 Chalcone/stilbene_synthase_N
IPR011141 Polyketide_synthase_type-III
IPR016039 Thiolase-like
PANTHERiPTHR11877 PTHR11877, 1 hit
PfamiView protein in Pfam
PF02797 Chal_sti_synt_C, 1 hit
PF00195 Chal_sti_synt_N, 1 hit
PIRSFiPIRSF000451 PKS_III, 1 hit
SUPFAMiSSF53901 SSF53901, 2 hits
PROSITEiView protein in PROSITE
PS00441 CHALCONE_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

P49440-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSVSEIRQA QRAEGPATIL AIGTATPSNC VDQSTYPDYY FRITNSEHMT
60 70 80 90 100
DLKEKFQRMC DKSMIKKRYM HLNEEILKEN PNMCAYMAPS LDARQDIVVV
110 120 130 140 150
EVPKLGKEAA VKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL
160 170 180 190 200
RPYVKRYMMY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG
210 220 230 240 250
PSDTHLDSLV GQALFGDGAA AVIVGSDPIP QIEKPLFELV WTAQTIAPDS
260 270 280 290 300
DGAIDGHLRE VGLTFHLLKD VPGIVSKNIG KALFEAFNPL NISDYNSIFW
310 320 330 340 350
IAHPGGPAIL DQVEQKLGLK PEKMKATRDV LSDYGNMSGA CVLFILDEMR
360 370 380
RKSAEKGLKT TGEGLEWGVL FGFGPGLTIE TVVLHSVAI
Length:389
Mass (Da):42,654
Last modified:February 1, 1996 - v1
Checksum:i25F13C3C4D654F47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06411 mRNA Translation: CAA29700.1

Similar proteinsi

Entry informationi

Entry nameiCHSY_PHAVU
AccessioniPrimary (citable) accession number: P49440
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health