P49401 (RS4_XENLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
40S ribosomal protein S4

Gene names

Name:	rps4
Synonyms:	rps4x

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein S4e family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 263	262	40S ribosomal protein S4		PRO_0000130826
Regions
	Domain	42 – 104	63	S4 RNA-binding
Experimental info
	Sequence conflict	116	1	S → A in AAH70591. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P49401 [UniParc]. Last modified January 23, 2007. Version 4. Checksum: 9AA3A805BB8146AB	FASTA	263	29,665
	10 20 30 40 50 60 MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE 70 80 90 100 110 120 VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR LVYDTKGRFA VHRITSEEAK 130 140 150 160 170 180 YKLCKVRKTW VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL 190 200 210 220 230 240 CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNNFAT RLSNIFVIGK GNKPWISLPR 250 260 GKGIRLTIAE ERDKRLAAKQ SSG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung and Ovary.
[2]	"Analysis of mRNAs under translational control during Xenopus embryogenesis: isolation of new ribosomal protein clones." Loreni F., Francesconi A., Jappelli R., Amaldi F. Nucleic Acids Res. 20:1859-1863(1992) [PubMed: 1579486] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 112-144.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC070591 mRNA. Translation: AAH70591.1. BC106700 mRNA. Translation: AAI06701.1. X64206 mRNA. No translation available.
PIR	S22608.
RefSeq	NP_001084941.1. NM_001091472.1. NP_001090472.1. NM_001097003.1.
UniGene	Xl.21377. Xl.70083.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	P49401.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	431998. 779385.
KEGG	xla:431998. xla:779385.
Organism-specific databases
CTD	39484. 6191.
Xenbase	XB-GENE-967208. rps4x.
Phylogenomic databases
HOVERGEN	HBG000935.
Family and domain databases
InterPro	IPR005824. KOW. IPR000876. Ribosomal_S4e. IPR013845. Ribosomal_S4e_central. IPR013843. Ribosomal_S4e_N. IPR018199. Ribosomal_S4e_N_CS. IPR002942. S4_RNA-bd. [Graphical view]
KO	K02987.
PANTHER	PTHR11581. Ribosomal_S4E. 1 hit.
Pfam	PF00467. KOW. 1 hit. PF00900. Ribosomal_S4e. 1 hit. PF08071. RS4NT. 1 hit. PF01479. S4. 1 hit. [Graphical view]
PIRSF	PIRSF002116. Ribosomal_S4. 1 hit.
ProDom	PD002667. Ribosomal_S4e_central. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00363. S4. 1 hit. [Graphical view]
PROSITE	PS00528. RIBOSOMAL_S4E. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_XENLA

Accession

Primary (citable) accession number: P49401
Secondary accession number(s): Q3B893, Q6NRW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	January 23, 2007
Last modified:	November 16, 2011
This is version 61 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program