P49372 (ALL1_APIGR) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 60.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Major allergen Api g 1 Alternative name(s): Allergen Api g 1.0101 Allergen Api g I Allergen=Api g 1 |
| Organism | Apium graveolens (Celery) |
| Taxonomic identifier | 4045 [NCBI] |
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiaceae › Apioideae › apioid superclade › Apieae › Apium |
Protein attributes
| Sequence length | 154 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Allergenic properties | Causes an allergic reaction in human. |
| Sequence similarities | Belongs to the BetVI family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Plant defense |
| Disease | Allergen |
| Molecular function | Pathogenesis-related protein |
| Technical term | 3D-structure |
| Gene Ontology (GO) | |
| Biological process | defense response Inferred from electronic annotation. Source: UniProtKB-KW response to biotic stimulusInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||||||||||||||||||||||||||
Molecule processing | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 154 | 154 | Major allergen Api g 1 | PRO_0000154172 | ||||||||||||||||||||||||||||
Secondary structure | ||||||||||||||||||||||||||||||||
Helix Strand Turn | ||||||||||||||||||||||||||||||||
| Beta strand | 3 – 14 | 12 | ||||||||||||||||||||||||||||||
| Helix | 16 – 23 | 8 | ||||||||||||||||||||||||||||||
| Helix | 27 – 34 | 8 | ||||||||||||||||||||||||||||||
| Helix | 36 – 38 | 3 | ||||||||||||||||||||||||||||||
| Beta strand | 40 – 49 | 10 | ||||||||||||||||||||||||||||||
| Beta strand | 53 – 57 | 5 | ||||||||||||||||||||||||||||||
| Beta strand | 66 – 75 | 10 | ||||||||||||||||||||||||||||||
| Turn | 76 – 79 | 4 | ||||||||||||||||||||||||||||||
| Beta strand | 80 – 88 | 9 | ||||||||||||||||||||||||||||||
| Helix | 89 – 91 | 3 | ||||||||||||||||||||||||||||||
| Turn | 92 – 94 | 3 | ||||||||||||||||||||||||||||||
| Beta strand | 95 – 106 | 12 | ||||||||||||||||||||||||||||||
| Beta strand | 112 – 123 | 12 | ||||||||||||||||||||||||||||||
| Helix | 130 – 153 | 24 | ||||||||||||||||||||||||||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Molecular characterization of Api g 1, the major allergen of celery (Apium graveolens), and its immunological and structural relationships to a group of 17-kDa tree pollen allergens." Breiteneder H., Hoffmann-Sommergruber K., O'Riordain G., Susani M., Ahorn H., Ebner C., Kraft D., Scheiner O. Eur. J. Biochem. 233:484-489(1995) [PubMed: 7588792] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Bulb and Leaf. |
| [2] | "Crystal structure of the major celery allergen Api g 1: molecular analysis of cross-reactivity." Schirmer T., Hoffimann-Sommergrube K., Susani M., Breiteneder H., Markovic-Housley Z. J. Mol. Biol. 351:1101-1109(2005) [PubMed: 16051263] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS). |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | Z48967 mRNA. Translation: CAA88831.1. | ||||||||||||
| PIR | S63984. | ||||||||||||
3D structure databases | |||||||||||||
| PDBe RCSB PDB PDBj |
| ||||||||||||
| ProteinModelPortal | P49372. | ||||||||||||
| SMR | P49372. Positions 2-154. | ||||||||||||
| ModBase | Search... | ||||||||||||
Protein family/group databases | |||||||||||||
| Allergome | 40. Api g 1. 41. Api g 1.0101. | ||||||||||||
Protocols and materials databases | |||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||
Family and domain databases | |||||||||||||
| InterPro | IPR000916. Bet_v_I_dom. IPR023393. START-like_dom. [Graphical view] | ||||||||||||
| Gene3D | G3DSA:3.30.530.20. G3DSA:3.30.530.20. 1 hit. | ||||||||||||
| Pfam | PF00407. Bet_v_1. 1 hit. [Graphical view] | ||||||||||||
| PROSITE | PS00451. PATHOGENESIS_BETVI. 1 hit. [Graphical view] | ||||||||||||
| ProtoNet | Search... | ||||||||||||
Entry information
| Entry name | ALL1_APIGR | ||||||||
| Accession | Primary (citable) accession number: P49372 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Allergens Nomenclature of allergens and list of entries |
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with