Reviewed,
UniProtKB/Swiss-Prot P49372 (ALL1_APIGR)
Last modified
November 24, 2009.
Version 52.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Major allergen Api g 1 Alternative name(s): Allergen Api g I Allergen Api g 1.0101 Allergen=Api g 1 |
| Organism | Apium graveolens (Celery) |
| Taxonomic identifier | 4045 [NCBI] |
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiaceae › Apioideae › apioid superclade › Apium clade › Apium |
Protein attributes
| Sequence length | 154 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Allergenic properties | Causes an allergic reaction in human. |
| Sequence similarities | Belongs to the BetVI family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Plant defense |
| Disease | Allergen |
| Molecular function | Pathogenesis-related protein |
| Technical term | 3D-structure |
| Gene Ontology (GO) | |
| Biological process | defense response Inferred from electronic annotation. Source: UniProtKB-KW response to biotic stimulusInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||||||||||||||||||||||||||
Molecule processing | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 154 | 154 | Major allergen Api g 1 | PRO_0000154172 | ||||||||||||||||||||||||||||
Secondary structure | ||||||||||||||||||||||||||||||||
Helix Strand Turn | ||||||||||||||||||||||||||||||||
| Beta strand | 3 – 14 | 12 | ||||||||||||||||||||||||||||||
| Helix | 16 – 23 | 8 | ||||||||||||||||||||||||||||||
| Helix | 27 – 34 | 8 | ||||||||||||||||||||||||||||||
| Helix | 36 – 38 | 3 | ||||||||||||||||||||||||||||||
| Beta strand | 40 – 49 | 10 | ||||||||||||||||||||||||||||||
| Beta strand | 53 – 57 | 5 | ||||||||||||||||||||||||||||||
| Beta strand | 66 – 75 | 10 | ||||||||||||||||||||||||||||||
| Turn | 76 – 79 | 4 | ||||||||||||||||||||||||||||||
| Beta strand | 80 – 88 | 9 | ||||||||||||||||||||||||||||||
| Helix | 89 – 91 | 3 | ||||||||||||||||||||||||||||||
| Turn | 92 – 94 | 3 | ||||||||||||||||||||||||||||||
| Beta strand | 95 – 106 | 12 | ||||||||||||||||||||||||||||||
| Beta strand | 112 – 123 | 12 | ||||||||||||||||||||||||||||||
| Helix | 130 – 153 | 24 | ||||||||||||||||||||||||||||||
Sequences
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References
| [1] | "Molecular characterization of Api g 1, the major allergen of celery (Apium graveolens), and its immunological and structural relationships to a group of 17-kDa tree pollen allergens." Breiteneder H., Hoffmann-Sommergruber K., O'Riordain G., Susani M., Ahorn H., Ebner C., Kraft D., Scheiner O. Eur. J. Biochem. 233:484-489(1995) [PubMed: 7588792] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Bulb and Leaf. |
| [2] | "Crystal structure of the major celery allergen Api g 1: molecular analysis of cross-reactivity." Schirmer T., Hoffimann-Sommergrube K., Susani M., Breiteneder H., Markovic-Housley Z. J. Mol. Biol. 351:1101-1109(2005) [PubMed: 16051263] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS). |
Cross-references
Sequence databases | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Z48967 mRNA. Translation: CAA88831.1. | |||||||||||||
| PIR | S63984. | ||||||||||||
3D structure databases | |||||||||||||
| |||||||||||||
| ModBase | Search... | ||||||||||||
Family and domain databases | |||||||||||||
| InterPro | IPR000916. Bet_v_I. [Graphical view] | ||||||||||||
| Pfam | PF00407. Bet_v_I. 1 hit. [Graphical view] | ||||||||||||
| PRINTS | PR00634. BETALLERGEN. | ||||||||||||
| PROSITE | PS00451. PATHOGENESIS_BETVI. 1 hit. [Graphical view] | ||||||||||||
| ProtoNet | Search... | ||||||||||||
Entry information
| Entry name | ALL1_APIGR | ||||||||
| Accession | Primary (citable) accession number: P49372 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Allergens Nomenclature of allergens and list of entries |
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

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