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P49332 (GSTXC_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutathione S-transferase parC

EC=2.5.1.18
Alternative name(s):
Auxin-regulated protein parC
Gene names
Name:PARC
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Tissue specificity

Abundant in seedlings and roots. It is also found in the shoot tips, flowers and leaves.

Induction

By auxin.

Sequence similarities

Belongs to the GST superfamily. Phi family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processAuxin signaling pathway
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processauxin-activated signaling pathway

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Probable glutathione S-transferase parC
PRO_0000185864

Regions

Domain4 – 8380GST N-terminal
Domain90 – 214125GST C-terminal
Region67 – 682Glutathione binding By similarity

Sites

Binding site141Glutathione By similarity
Binding site411Glutathione By similarity
Binding site551Glutathione; via amide nitrogen and carbonyl oxygen By similarity

Sequences

Sequence LengthMass (Da)Tools
P49332 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 18D27C69857EB3AE

FASTA22125,743
        10         20         30         40         50         60 
MANEEVILLD FWPSMFGMRL RIALAEKEIK YEYKQEDLRN KSPLLLQMNP IHKKIPVLIH 

        70         80         90        100        110        120 
NGKPICESII AVEYIEEVWK DKAPSLLPSD PYDRAQARFW ADYIDKKLYD FGRKLWATKG 

       130        140        150        160        170        180 
EEQEAAKKDF IECLKVLEGA LGDRPYFGGE SFGFVDIALI GFYSWFYAYE TFGNFSTEAE 

       190        200        210        220 
CPKFVAWAKR CMQRESVAKS LPDQPKVLEF VKVLRQKFGL E 

« Hide

References

[1]"Differential expression of an auxin-regulated gene, parC, and a novel related gene, C-7 from tobacco mesophyll protoplasts in response to external stimuli and plant tissues."
Takahashi Y., Nagata T.
Plant Cell Physiol. 33:779-787(1992)
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Xanthi NC.
Tissue: Leaf mesophyll.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X64398 mRNA. Translation: CAA45740.1.
PIRS19185.

3D structure databases

ProteinModelPortalP49332.
SMRP49332. Positions 3-220.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTXC_TOBAC
AccessionPrimary (citable) accession number: P49332
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families