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P49332

- GSTXC_TOBAC

UniProt

P49332 - GSTXC_TOBAC

Protein

Probable glutathione S-transferase parC

Gene

PARC

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    • Comment

    Functioni

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei14 – 141GlutathioneBy similarity
    Binding sitei41 – 411GlutathioneBy similarity
    Binding sitei55 – 551Glutathione; via amide nitrogen and carbonyl oxygenBy similarity

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. auxin-activated signaling pathway Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Auxin signaling pathway

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glutathione S-transferase parC (EC:2.5.1.18)
    Alternative name(s):
    Auxin-regulated protein parC
    Gene namesi
    Name:PARC
    OrganismiNicotiana tabacum (Common tobacco)
    Taxonomic identifieri4097 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Probable glutathione S-transferase parCPRO_0000185864Add
    BLAST

    Expressioni

    Tissue specificityi

    Abundant in seedlings and roots. It is also found in the shoot tips, flowers and leaves.

    Inductioni

    By auxin.

    Structurei

    3D structure databases

    ProteinModelPortaliP49332.
    SMRiP49332. Positions 3-220.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 8380GST N-terminalAdd
    BLAST
    Domaini90 – 214125GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni67 – 682Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Phi family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P49332-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANEEVILLD FWPSMFGMRL RIALAEKEIK YEYKQEDLRN KSPLLLQMNP    50
    IHKKIPVLIH NGKPICESII AVEYIEEVWK DKAPSLLPSD PYDRAQARFW 100
    ADYIDKKLYD FGRKLWATKG EEQEAAKKDF IECLKVLEGA LGDRPYFGGE 150
    SFGFVDIALI GFYSWFYAYE TFGNFSTEAE CPKFVAWAKR CMQRESVAKS 200
    LPDQPKVLEF VKVLRQKFGL E 221
    Length:221
    Mass (Da):25,743
    Last modified:February 1, 1996 - v1
    Checksum:i18D27C69857EB3AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X64398 mRNA. Translation: CAA45740.1.
    PIRiS19185.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X64398 mRNA. Translation: CAA45740.1 .
    PIRi S19185.

    3D structure databases

    ProteinModelPortali P49332.
    SMRi P49332. Positions 3-220.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Differential expression of an auxin-regulated gene, parC, and a novel related gene, C-7 from tobacco mesophyll protoplasts in response to external stimuli and plant tissues."
      Takahashi Y., Nagata T.
      Plant Cell Physiol. 33:779-787(1992)
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Xanthi NC.
      Tissue: Leaf mesophyll.

    Entry informationi

    Entry nameiGSTXC_TOBAC
    AccessioniPrimary (citable) accession number: P49332
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3