P49332 (GSTXC_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable glutathione S-transferase parC
EC=2.5.1.18

Alternative name(s):
Auxin-regulated protein parC

Gene names

Name:

PARC

Organism

Nicotiana tabacum (Common tobacco)

Taxonomic identifier

4097 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Tissue specificity	Abundant in seedlings and roots. It is also found in the shoot tips, flowers and leaves.
Induction	By auxin.
Sequence similarities	Belongs to the GST superfamily. Phi family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Auxin signaling pathway
Molecular function	Transferase
Gene Ontology (GO)
Biological_process	auxin mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Probable glutathione S-transferase parC		PRO_0000185864
Regions
	Domain	4 – 83	80	GST N-terminal
	Domain	90 – 214	125	GST C-terminal
	Region	67 – 68	2	Glutathione binding By similarity
Sites
	Binding site	14	1	Glutathione By similarity
	Binding site	41	1	Glutathione By similarity
	Binding site	55	1	Glutathione; via amide nitrogen and carbonyl oxygen By similarity

Sequences

	Sequence		Length	Mass (Da)
	P49332 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 18D27C69857EB3AE	FASTA	221	25,743
	10 20 30 40 50 60 MANEEVILLD FWPSMFGMRL RIALAEKEIK YEYKQEDLRN KSPLLLQMNP IHKKIPVLIH 70 80 90 100 110 120 NGKPICESII AVEYIEEVWK DKAPSLLPSD PYDRAQARFW ADYIDKKLYD FGRKLWATKG 130 140 150 160 170 180 EEQEAAKKDF IECLKVLEGA LGDRPYFGGE SFGFVDIALI GFYSWFYAYE TFGNFSTEAE 190 200 210 220 CPKFVAWAKR CMQRESVAKS LPDQPKVLEF VKVLRQKFGL E

References

[1]

"Differential expression of an auxin-regulated gene, parC, and a novel related gene, C-7 from tobacco mesophyll protoplasts in response to external stimuli and plant tissues." Takahashi Y., Nagata T. Plant Cell Physiol. 33:779-787(1992) Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Xanthi NC. Tissue: Leaf mesophyll.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X64398 mRNA. Translation: CAA45740.1.
PIR	S19185.
3D structure databases
ProteinModelPortal	P49332.
SMR	P49332. Positions 3-220.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.20.1050.10. 1 hit. 3.40.30.10. 1 hit.
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSTXC_TOBAC

Accession

Primary (citable) accession number: P49332

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	March 6, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program