ID   CATA3_NICPL             Reviewed;         492 AA.
AC   P49317;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   16-JUN-2009, entry version 54.
DE   RecName: Full=Catalase isozyme 3;
DE            EC=1.11.1.6;
GN   Name=CAT3;
OS   Nicotiana plumbaginifolia (Leadwort-leaved tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4092;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Flower;
RX   MEDLINE=95010681; PubMed=7925949; DOI=10.1016/0014-5793(94)00923-6;
RA   Willekens H., Villarroel R., van Montagu M., Inze D., van Camp W.;
RT   "Molecular identification of catalases from Nicotiana plumbaginifolia
RT   (L.).";
RL   FEBS Lett. 352:79-83(1994).
CC   -!- FUNCTION: Occurs in almost all aerobically respiring organisms and
CC       serves to protect cells from the toxic effects of hydrogen
CC       peroxide.
CC   -!- CATALYTIC ACTIVITY: 2 H(2)O(2) = O(2) + 2 H(2)O.
CC   -!- COFACTOR: Heme group.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Peroxisome (Potential).
CC   -!- INDUCTION: By 3-aminotriazole.
CC   -!- SIMILARITY: Belongs to the catalase family.
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DR   EMBL; Z36977; CAA85426.1; -; mRNA.
DR   PIR; T16969; T16969.
DR   HSSP; P46206; 1M7S.
DR   BRENDA; 1.11.1.6; 257040.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0004096; F:catalase activity; IEA:EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002226; Catalase.
DR   InterPro; IPR010582; Catalase-rel_immune_responsive.
DR   InterPro; IPR011614; Catalase_N.
DR   InterPro; IPR018028; Catalase_rel_subgroup.
DR   Gene3D; G3DSA:2.40.180.10; Catalase_N; 1.
DR   PANTHER; PTHR11465; Catalase; 1.
DR   Pfam; PF00199; Catalase; 1.
DR   Pfam; PF06628; Catalase-rel; 1.
DR   PRINTS; PR00067; CATALASE.
DR   ProDom; PD000510; Catalase; 1.
DR   PROSITE; PS00437; CATALASE_1; 1.
DR   PROSITE; PS00438; CATALASE_2; 1.
DR   PROSITE; PS51402; CATALASE_3; 1.
PE   2: Evidence at transcript level;
KW   Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase;
KW   Peroxidase; Peroxisome.
FT   CHAIN         1    492       Catalase isozyme 3.
FT                                /FTId=PRO_0000084951.
FT   ACT_SITE     65     65       By similarity.
FT   ACT_SITE    138    138       By similarity.
FT   METAL       348    348       Iron (heme axial ligand) (By similarity).
SQ   SEQUENCE   492 AA;  57017 MW;  2A49AD89CC6FB4D5 CRC64;
     MDPYKYRPSS ANNSPFWTTN SGAPVWNNNS SMTVGTRGPI LLEDYHLVEK LANFDRERIP
     ERVVHARGAS AKGFFEVTHD ITHLTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR
     GFAVKFYTRE GNFDLVGNNF PVFFVRDGMK FPDMVHALKP NPKSHIQENW RILDFFSHHP
     ESLHMFSFLF DDLGVPQDYR HMEGSGVNTY MLINKAGKAH YVKFHWKPTC GVKCLLEEEA
     IKVGGANHSH ATKDLYDSIA AGNYPEWKLF IQIIDPDHED RFDFDPLDVT KTWPEDILPL
     QPVGRLVLNK NIDNFFAENE QLAFWPAIVV PGVYCSDDKL LQTRIFSYSD AQRHRLGPNY
     LQLPVNAPKC AHHNNHHEGF MNFMHRDEEV NYFPSRFDPC RHAEQYPIPP CVLTGKRDKC
     IIEKENNFKQ PGERYRSWAP DRQERFICRW VDALSDPRVT HEIRSIWFSY WSQADKTLGQ
     KIASRLNVRP TM
//