Reviewed, UniProtKB/Swiss-Prot P49317 (CATA3_NICPL)

Names and origin

Protein names

Recommended name:
    Catalase isozyme 3
    EC=1.11.1.6

Gene names

Name:

CAT3

Organism

Nicotiana plumbaginifolia (Leadwort-leaved tobacco)

Taxonomic identifier

4092 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Subunit structure	Homotetramer By similarity.
Subcellular location	Peroxisome Potential.
Induction	By 3-aminotriazole.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Catalase isozyme 3		PRO_0000084951
Sites
	Active site	65	1	By similarity
	Active site	138	1	By similarity
	Metal binding	348	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P49317-1 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 2A49AD89CC6FB4D5	FASTA	492	57,017
	10 20 30 40 50 60 MDPYKYRPSS ANNSPFWTTN SGAPVWNNNS SMTVGTRGPI LLEDYHLVEK LANFDRERIP 70 80 90 100 110 120 ERVVHARGAS AKGFFEVTHD ITHLTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR 130 140 150 160 170 180 GFAVKFYTRE GNFDLVGNNF PVFFVRDGMK FPDMVHALKP NPKSHIQENW RILDFFSHHP 190 200 210 220 230 240 ESLHMFSFLF DDLGVPQDYR HMEGSGVNTY MLINKAGKAH YVKFHWKPTC GVKCLLEEEA 250 260 270 280 290 300 IKVGGANHSH ATKDLYDSIA AGNYPEWKLF IQIIDPDHED RFDFDPLDVT KTWPEDILPL 310 320 330 340 350 360 QPVGRLVLNK NIDNFFAENE QLAFWPAIVV PGVYCSDDKL LQTRIFSYSD AQRHRLGPNY 370 380 390 400 410 420 LQLPVNAPKC AHHNNHHEGF MNFMHRDEEV NYFPSRFDPC RHAEQYPIPP CVLTGKRDKC 430 440 450 460 470 480 IIEKENNFKQ PGERYRSWAP DRQERFICRW VDALSDPRVT HEIRSIWFSY WSQADKTLGQ 490 KIASRLNVRP TM

References

[1]	"Molecular identification of catalases from Nicotiana plumbaginifolia (L.)." Willekens H., Villarroel R., van Montagu M., Inze D., van Camp W. FEBS Lett. 352:79-83(1994) [PubMed: 7925949] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Flower.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z36977 mRNA. Translation: CAA85426.1.
PIR	T16969.
3D structure databases
SMR	P49317. Positions 17-489.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.6. 257040.
Family and domain databases
InterPro	IPR002226. Catalase. IPR020835. Catalase-like_haem-dep. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA3_NICPL

Accession

Primary (citable) accession number: P49317

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	January 19, 2010
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)