Reviewed, UniProtKB/Swiss-Prot P49315 (CATA1_NICPL)

Names and origin

Protein names

Recommended name:
    Catalase isozyme 1
    EC=1.11.1.6

Gene names

Name:

CAT1

Organism

Nicotiana plumbaginifolia (Leadwort-leaved tobacco)

Taxonomic identifier

4092 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	485 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group.
Subunit structure	Homotetramer By similarity.
Subcellular location	PeroxisomePotential.
Induction	By paraquat and 3-aminotriazole.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 485	›485	Catalase isozyme 1		PRO_0000084949
Sites
	Active site	58	1	By similarity
	Active site	131	1	By similarity
	Metal binding	341	1	Iron (heme axial ligand) By similarity
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P49315-1 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 00BA53BEF7699A13	FASTA	485	55,850
	10 20 30 40 50 60 PSSAFNSPFC TTNSGAPVFN NNSSLTVGAR GPVLLEDYHL VEKLANFDRE RVPERVVHAR 70 80 90 100 110 120 GASAKGFFEV THDITHLTCA DFLRAPGVQT PVIVRFSTVI HERGSPETLR DPRGFAVKFY 130 140 150 160 170 180 TREGNFDLVG NNFPVFFIRD GMKFPDMVHA LKPNPKSHIQ ENWRVLDFFS HVPESLHMFT 190 200 210 220 230 240 FLFDDIGIPQ DYRHMDGSGV HTFTLINKAG KSTYVKFHWK PTCGVKSLLE DEAARVGGAN 250 260 270 280 290 300 HSHATQDLYD SIAAGNYPEW KLFIQTMDPD HEDRFDFDPL DVTKTWPEDI LPLQPVGRLV 310 320 330 340 350 360 LNKNIDNFSN ENEQLAFCPS IVVPGVYYSD DKMLQTRIFS YSDTQRYRLG PNYLQLPANA 370 380 390 400 410 420 PKCAHHNNHY DGSMNFMHRD EEIDYFPSRY DPVRHAEKYP IPSTMCTGKR EKCVIQKENN 430 440 450 460 470 480 FKQPGERYRS FTPDRQERFI RRWVETLSDP RITYEIRSIW ISYWSQADKS LGQKLASRLN VRPSI

References

[1]	"Molecular identification of catalases from Nicotiana plumbaginifolia (L.)." Willekens H., Villarroel R., van Montagu M., Inze D., van Camp W. FEBS Lett. 352:79-83(1994) [PubMed: 7925949] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z36975 mRNA. Translation: CAA85424.1.
PIR	S48650.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA1_NICPL

Accession

Primary (citable) accession number: P49315

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	November 25, 2008
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)