SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P49273

- ALL7_DERPT

UniProt

P49273 - ALL7_DERPT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Mite allergen Der p 7

Gene
DERP7
Organism
Dermatophagoides pteronyssinus (European house dust mite)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite allergen Der p 7
Alternative name(s):
Allergen Der p VII
Allergen: Der p 7
Gene namesi
Name:DERP7
OrganismiDermatophagoides pteronyssinus (European house dust mite)
Taxonomic identifieri6956 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei321. Der p 7.
3268. Der p 7.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed predictionAdd
BLAST
Chaini18 – 215198Mite allergen Der p 7PRO_0000001185Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi151 – 1511N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Structurei

Secondary structure

1
215
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi22 – 4221
Turni45 – 484
Beta strandi49 – 513
Beta strandi54 – 596
Beta strandi63 – 653
Beta strandi68 – 7912
Helixi81 – 833
Beta strandi91 – 955
Beta strandi98 – 10710
Beta strandi112 – 1209
Beta strandi128 – 14619
Beta strandi152 – 1598
Beta strandi165 – 1695
Helixi177 – 18812
Turni189 – 1924
Helixi193 – 21018
Turni211 – 2144

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3H4ZX-ray2.35A/B/C17-215[»]

Miscellaneous databases

EvolutionaryTraceiP49273.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR020234. Mite_allergen_group-7.
[Graphical view]
ProDomiPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P49273-1 [UniParc]FASTAAdd to Basket

« Hide

MMKLLLIAAA AFVAVSADPI HYDKITEEIN KAVDEAVAAI EKSETFDPMK    50
VPDHSDKFER HIGIIDLKGE LDMRNIQVRG LKQMKRVGDA NVKSEDGVVK 100
AHLLVGVHDD VVSMEYDLAY KLGDLHPNTH VISDIQDFVV ELSLEVSEEG 150
NMTLTSFEVR QFANVVNHIG GLSILDPIFA VLSDVLTAIF QDTVRAEMTK 200
VLAPAFKKEL ERNNQ 215
Length:215
Mass (Da):23,881
Last modified:February 1, 1996 - v1
Checksum:i63AD03DB5C8CB1C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U37044 mRNA. Translation: AAA80264.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U37044 mRNA. Translation: AAA80264.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3H4Z X-ray 2.35 A/B/C 17-215 [» ]
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 321. Der p 7.
3268. Der p 7.0101.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P49273.

Family and domain databases

InterProi IPR020234. Mite_allergen_group-7.
[Graphical view ]
ProDomi PD037435. Mite_group-7_allergen. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of a house dust mite allergen with common antibody binding specificities with multiple components in mite extracts."
    Shen H.-D., Chua K.-Y., Lin K.-L., Hsieh K.-H., Thomas W.R.
    Clin. Exp. Allergy 23:934-940(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiALL7_DERPT
AccessioniPrimary (citable) accession number: P49273
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 3, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi