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P49273 (ALL7_DERPT) Reviewed, UniProtKB/Swiss-Prot

Last modified October 3, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mite allergen Der p 7
Alternative name(s):
Allergen Der p VII
Allergen=Der p 7
Gene names
Name:DERP7
OrganismDermatophagoides pteronyssinus (European house dust mite)
Taxonomic identifier6956 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted.

Allergenic properties

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Sequence similarities

Belongs to the mite group 7 allergen family.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   DomainSignal
   PTMGlycoprotein
   Technical term3D-structure
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 215198Mite allergen Der p 7
PRO_0000001185

Amino acid modifications

Glycosylation1511N-linked (GlcNAc...) Potential

Secondary structure

............................... 215
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P49273 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 63AD03DB5C8CB1C0

FASTA21523,881
        10         20         30         40         50         60 
MMKLLLIAAA AFVAVSADPI HYDKITEEIN KAVDEAVAAI EKSETFDPMK VPDHSDKFER 

        70         80         90        100        110        120 
HIGIIDLKGE LDMRNIQVRG LKQMKRVGDA NVKSEDGVVK AHLLVGVHDD VVSMEYDLAY 

       130        140        150        160        170        180 
KLGDLHPNTH VISDIQDFVV ELSLEVSEEG NMTLTSFEVR QFANVVNHIG GLSILDPIFA 

       190        200        210 
VLSDVLTAIF QDTVRAEMTK VLAPAFKKEL ERNNQ 

« Hide

References

[1]"Molecular cloning of a house dust mite allergen with common antibody binding specificities with multiple components in mite extracts."
Shen H.-D., Chua K.-Y., Lin K.-L., Hsieh K.-H., Thomas W.R.
Clin. Exp. Allergy 23:934-940(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U37044 mRNA. Translation: AAA80264.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3H4ZX-ray2.35A/B/C17-215[»]
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome321. Der p 7.
3268. Der p 7.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR020234. Mite_allergen_group-7.
[Graphical view]
ProDomPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Other

EvolutionaryTraceP49273.

Entry information

Entry nameALL7_DERPT
AccessionPrimary (citable) accession number: P49273
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 3, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Allergens

Nomenclature of allergens and list of entries