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Protein

40S ribosomal protein S12

Gene

rps-12

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-6791226. Major pathway of rRNA processing in the nucleolus.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-CEL-72702. Ribosomal scanning and start codon recognition.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12
Gene namesi
Name:rps-12
ORF Names:F54E7.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF54E7.2; CE26896; WBGene00004481; rps-12.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14014040S ribosomal protein S12PRO_0000122329Add
BLAST

Proteomic databases

EPDiP49196.
PaxDbiP49196.

2D gel databases

World-2DPAGE0020:P49196.

PTM databases

iPTMnetiP49196.

Expressioni

Gene expression databases

BgeeiWBGene00004481.

Interactioni

Protein-protein interaction databases

BioGridi41013. 4 interactions.
IntActiP49196. 1 interaction.
STRINGi6239.F54E7.2.2.

Structurei

3D structure databases

ProteinModelPortaliP49196.
SMRiP49196. Positions 20-136.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S12e family.Curated

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOGENOMiHOG000210688.
InParanoidiP49196.
KOiK02951.
OMAiNCDEPTY.
OrthoDBiEOG091G0UB5.
PhylomeDBiP49196.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
[Graphical view]
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiPS01189. RIBOSOMAL_S12E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P49196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDAGGDVQV APAAVAQGPM DKEGALRAVL RAAHHADGLA KGLHETCKAL
60 70 80 90 100
DKREAHFCVL AENCDEPQYV KLVETLCAEH QIPLIKVADK KIIGEYCGLC
110 120 130 140
KYDKEGKARK VVGCSSAVVT NWGNEEQGRA ILTDYFASKN
Length:140
Mass (Da):15,069
Last modified:August 29, 2001 - v2
Checksum:i3B6E932D087B77AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080172 Genomic DNA. Translation: CCD61763.1.
RefSeqiNP_498221.1. NM_065820.5.
UniGeneiCel.18085.

Genome annotation databases

EnsemblMetazoaiF54E7.2.1; F54E7.2.1; WBGene00004481.
F54E7.2.2; F54E7.2.2; WBGene00004481.
F54E7.2.3; F54E7.2.3; WBGene00004481.
GeneIDi175786.
KEGGicel:CELE_F54E7.2.
UCSCiF54E7.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080172 Genomic DNA. Translation: CCD61763.1.
RefSeqiNP_498221.1. NM_065820.5.
UniGeneiCel.18085.

3D structure databases

ProteinModelPortaliP49196.
SMRiP49196. Positions 20-136.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi41013. 4 interactions.
IntActiP49196. 1 interaction.
STRINGi6239.F54E7.2.2.

PTM databases

iPTMnetiP49196.

2D gel databases

World-2DPAGE0020:P49196.

Proteomic databases

EPDiP49196.
PaxDbiP49196.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF54E7.2.1; F54E7.2.1; WBGene00004481.
F54E7.2.2; F54E7.2.2; WBGene00004481.
F54E7.2.3; F54E7.2.3; WBGene00004481.
GeneIDi175786.
KEGGicel:CELE_F54E7.2.
UCSCiF54E7.2.1. c. elegans.

Organism-specific databases

CTDi175786.
WormBaseiF54E7.2; CE26896; WBGene00004481; rps-12.

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOGENOMiHOG000210688.
InParanoidiP49196.
KOiK02951.
OMAiNCDEPTY.
OrthoDBiEOG091G0UB5.
PhylomeDBiP49196.

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-6791226. Major pathway of rRNA processing in the nucleolus.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-CEL-72702. Ribosomal scanning and start codon recognition.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP49196.

Gene expression databases

BgeeiWBGene00004481.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
[Graphical view]
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiPS01189. RIBOSOMAL_S12E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS12_CAEEL
AccessioniPrimary (citable) accession number: P49196
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 29, 2001
Last modified: September 7, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.