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Protein

40S ribosomal protein S12

Gene

rps-12

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-CEL-72702. Ribosomal scanning and start codon recognition.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12
Gene namesi
Name:rps-12
ORF Names:F54E7.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF54E7.2; CE26896; WBGene00004481; rps-12.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001223291 – 14040S ribosomal protein S12Add BLAST140

Proteomic databases

EPDiP49196.
PaxDbiP49196.
PeptideAtlasiP49196.
PRIDEiP49196.

2D gel databases

World-2DPAGEi0020:P49196.

PTM databases

iPTMnetiP49196.

Expressioni

Gene expression databases

BgeeiWBGene00004481.

Interactioni

Protein-protein interaction databases

BioGridi41013. 4 interactors.
IntActiP49196. 1 interactor.
STRINGi6239.F54E7.2.2.

Structurei

3D structure databases

ProteinModelPortaliP49196.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOGENOMiHOG000210688.
InParanoidiP49196.
KOiK02951.
OMAiGLRECAK.
OrthoDBiEOG091G0UB5.
PhylomeDBiP49196.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiView protein in InterPro
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiView protein in PROSITE
PS01189. RIBOSOMAL_S12E. 1 hit.

Sequencei

Sequence statusi: Complete.

P49196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDAGGDVQV APAAVAQGPM DKEGALRAVL RAAHHADGLA KGLHETCKAL
60 70 80 90 100
DKREAHFCVL AENCDEPQYV KLVETLCAEH QIPLIKVADK KIIGEYCGLC
110 120 130 140
KYDKEGKARK VVGCSSAVVT NWGNEEQGRA ILTDYFASKN
Length:140
Mass (Da):15,069
Last modified:August 29, 2001 - v2
Checksum:i3B6E932D087B77AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080172 Genomic DNA. Translation: CCD61763.1.
RefSeqiNP_498221.1. NM_065820.5.
UniGeneiCel.18085.

Genome annotation databases

EnsemblMetazoaiF54E7.2.1; F54E7.2.1; WBGene00004481.
F54E7.2.2; F54E7.2.2; WBGene00004481.
F54E7.2.3; F54E7.2.3; WBGene00004481.
GeneIDi175786.
KEGGicel:CELE_F54E7.2.
UCSCiF54E7.2.1. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRS12_CAEEL
AccessioniPrimary (citable) accession number: P49196
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 29, 2001
Last modified: June 7, 2017
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families