##gff-version 3
P49185	UniProtKB	Chain	1	411	.	.	.	ID=PRO_0000186264;Note=Mitogen-activated protein kinase 8	
P49185	UniProtKB	Domain	26	321	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P49185	UniProtKB	Region	368	411	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P49185	UniProtKB	Motif	183	185	.	.	.	Note=TXY	
P49185	UniProtKB	Compositional bias	386	411	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P49185	UniProtKB	Active site	151	151	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
P49185	UniProtKB	Binding site	32	40	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P49185	UniProtKB	Binding site	55	55	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P49185	UniProtKB	Modified residue	116	116	.	.	.	Note=S-nitrosocysteine%3B in inhibited form;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11121042;Dbxref=PMID:11121042	
P49185	UniProtKB	Modified residue	183	183	.	.	.	Note=Phosphothreonine%3B by MAP2K7;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P45983	
P49185	UniProtKB	Modified residue	185	185	.	.	.	Note=Phosphotyrosine%3B by MAP2K4;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P45983	
P49185	UniProtKB	Modified residue	377	377	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q91Y86	
P49185	UniProtKB	Mutagenesis	116	116	.	.	.	Note=Abolished inhibitory effect of IFN-gamma on JNK1 activity. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11121042;Dbxref=PMID:11121042