60S ribosomal protein L38 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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P49167 (RL38_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 91. History...

Clusters with 100%, 90%, 50% identity |

Documents (5) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
60S ribosomal protein L38

Gene names

Name:	RPL38
Ordered Locus Names:	YLR325C
ORF Names:	L8543.2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.5.
Miscellaneous	Present with 50200 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the ribosomal protein L38e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Traceable author statement Ref.3. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Traceable author statement Ref.3. Source: SGD
Molecular_function	structural constituent of ribosome Traceable author statement Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

Removed Ref.4

Chain

2 – 78

60S ribosomal protein L38

PRO_0000215445

Amino acid modifications

Modified residue

Phosphoserine Ref.8

Modified residue

Phosphoserine Ref.7 Ref.8

Sequences

Sequence

Length

Mass (Da)

Tools

P49167 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 0ECB20AD9A4A0D42
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FASTA

8,827

        10         20         30         40         50         60 
MAREITDIKQ FLELTRRADV KTATVKINKK LNKAGKPFRQ TKFKVRGSSS LYTLVINDAG 

        70 
KAKKLIQSLP PTLKVNRL

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. Hoheisel J.D. Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49, MASS SPECTROMETRY. Strain: YAL6B.
[8]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-48 AND SER-49, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U20618 Genomic DNA. Translation: AAB64512.1.
BK006945 Genomic DNA. Translation: DAA09633.1.

PIR

S53402.

RefSeq

NP_013429.1. NM_001182214.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IZS	electron microscopy	-	n	1-78	[»]
3U5E	X-ray	3.00	k	1-78	[»]
3U5I	X-ray	3.00	k	1-78	[»]
4B6A	electron microscopy	8.10	k	1-78	[»]

ProteinModelPortal

P49167.

SMR

P49167. Positions 2-78.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-3950N.

IntAct

P49167. 10 interactions.

MINT

MINT-477400.

STRING

4932.YLR325C.

Proteomic databases

PaxDb

P49167.

PeptideAtlas

P49167.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YLR325C; YLR325C; YLR325C.

GeneID

851035.

KEGG

sce:YLR325C.

Organism-specific databases

CYGD

YLR325c.

SGD

S000004317. RPL38.

Phylogenomic databases

eggNOG

NOG323549.

GeneTree

ENSGT00390000003718.

HOGENOM

HOG000188979.

K02923.

OMA

QTKFKVR.

OrthoDB

EOG4TB7N3.

Gene expression databases

Genevestigator

P49167.

GermOnline

YLR325C. Saccharomyces cerevisiae.

Family and domain databases

InterPro

IPR002675. Ribosomal_L38e.
[Graphical view]

PANTHER

PTHR10965. PTHR10965. 1 hit.

Pfam

PF01781. Ribosomal_L38e. 1 hit.
[Graphical view]

ProDom

PD010361. Ribosomal_L38e. 1 hit.
[Graphical view] [Entries sharing at least one domain]

ProtoNet

Search...

Other

NextBio

967628.

Entry information

Entry name

RL38_YEAST

Accession

Primary (citable) accession number: P49167
Secondary accession number(s): D6VYW7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program