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Protein

4-oxalocrotonate decarboxylase

Gene

xylI

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(3E)-2-oxohex-3-enedioate = 2-oxopent-4-enoate + CO2.

Pathwayi

GO - Molecular functioni

  1. 4-oxalocrotonate decarboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. toluene catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-12752.
UniPathwayiUPA00273.

Names & Taxonomyi

Protein namesi
Recommended name:
4-oxalocrotonate decarboxylase (EC:4.1.1.77)
Short name:
4-OD
Gene namesi
Name:xylI
Encoded oniPlasmid TOL pWW00 Publication
OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifieri303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2642644-oxalocrotonate decarboxylasePRO_0000066054Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP49155.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hydratase/decarboxylase family.Curated

Family and domain databases

Gene3Di3.90.850.10. 1 hit.
InterProiIPR017630. 4-oxalocrotonate_decarboxylase.
IPR002529. Fumarylacetoacetase_C.
IPR011234. Fumarylacetoacetase_C-rel.
[Graphical view]
PfamiPF01557. FAA_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56529. SSF56529. 1 hit.
TIGRFAMsiTIGR03218. catechol_dmpH. 1 hit.

Sequencei

Sequence statusi: Complete.

P49155-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRTLNREQV LALAEHIENA ELQAHDIHKV TNDYPEMTFA DAYTIQWEIR
60 70 80 90 100
RRKEERGNKI VGLKMGLTSW AKMAQMGVET PIYGFLADYF SVPDGGVVDC
110 120 130 140 150
SKLIHPKIEA EIAVVTKAPL VGPGCHIGDV IAAVDYVIPT VEVIDSRYEN
160 170 180 190 200
FKFDLISVVA DNASSTRYIT GGRMANLEDV DLRTLGVVME KNGEVVELGA
210 220 230 240 250
GAAVLGHPLS SVAMLANLLA ERGEHIPAGT FIMTGGITAA VAVAPGDNIT
260
VRYQGLGSVS ARFV
Length:264
Mass (Da):28,510
Last modified:January 31, 1996 - v1
Checksum:iDDF93ACC910722F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M94186 Genomic DNA. Translation: AAA25693.1.
PIRiS35224.
RefSeqiNP_542860.1. NC_003350.1.
WP_011005903.1. NC_003350.1.

Genome annotation databases

GeneIDi1218750.
KEGGipg:1218750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M94186 Genomic DNA. Translation: AAA25693.1.
PIRiS35224.
RefSeqiNP_542860.1. NC_003350.1.
WP_011005903.1. NC_003350.1.

3D structure databases

ProteinModelPortaliP49155.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1218750.
KEGGipg:1218750.

Enzyme and pathway databases

UniPathwayiUPA00273.
BioCyciMetaCyc:MONOMER-12752.

Family and domain databases

Gene3Di3.90.850.10. 1 hit.
InterProiIPR017630. 4-oxalocrotonate_decarboxylase.
IPR002529. Fumarylacetoacetase_C.
IPR011234. Fumarylacetoacetase_C-rel.
[Graphical view]
PfamiPF01557. FAA_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56529. SSF56529. 1 hit.
TIGRFAMsiTIGR03218. catechol_dmpH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the nucleotide sequences of the meta-cleavage pathway genes of TOL plasmid pWW0 from Pseudomonas putida with other meta-cleavage genes suggests that both single and multiple nucleotide substitutions contribute to enzyme evolution."
    Harayama S., Rekik M.
    Mol. Gen. Genet. 239:81-89(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 33015 / DSM 3931 / JCM 6156 / NCIMB 12182 / mt-2.

Entry informationi

Entry nameiXYLI_PSEPU
AccessioniPrimary (citable) accession number: P49155
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 1996
Last sequence update: January 31, 1996
Last modified: March 31, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.