P49155 (XYLI_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-oxalocrotonate decarboxylase
Short name=4-OD
EC=4.1.1.77

Gene names

Name:

xylI

Encoded on

Plasmid TOL pWW0

Organism

Pseudomonas putida (Arthrobacter siderocapsulatus)

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas putida group

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(3E)-2-oxohex-3-enedioate = 2-oxopent-4-enoate + CO2.
Pathway	Xenobiotic degradation; toluene degradation.
Sequence similarities	Belongs to the hydratase/decarboxylase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Molecular function	Lyase
Technical term	Plasmid
Gene Ontology (GO)
Biological_process	toluene catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	4-oxalocrotonate decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	4-oxalocrotonate decarboxylase		PRO_0000066054

Sequences

	Sequence		Length	Mass (Da)
	P49155 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: DDF93ACC910722F9	FASTA	264	28,510
	10 20 30 40 50 60 MNRTLNREQV LALAEHIENA ELQAHDIHKV TNDYPEMTFA DAYTIQWEIR RRKEERGNKI 70 80 90 100 110 120 VGLKMGLTSW AKMAQMGVET PIYGFLADYF SVPDGGVVDC SKLIHPKIEA EIAVVTKAPL 130 140 150 160 170 180 VGPGCHIGDV IAAVDYVIPT VEVIDSRYEN FKFDLISVVA DNASSTRYIT GGRMANLEDV 190 200 210 220 230 240 DLRTLGVVME KNGEVVELGA GAAVLGHPLS SVAMLANLLA ERGEHIPAGT FIMTGGITAA 250 260 VAVAPGDNIT VRYQGLGSVS ARFV

References

[1]

"Comparison of the nucleotide sequences of the meta-cleavage pathway genes of TOL plasmid pWW0 from Pseudomonas putida with other meta-cleavage genes suggests that both single and multiple nucleotide substitutions contribute to enzyme evolution." Harayama S., Rekik M. Mol. Gen. Genet. 239:81-89(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 33015 / DSM 3931 / JCM 6156 / NCIMB 12182 / mt-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M94186 Genomic DNA. Translation: AAA25693.1.
PIR	S35224.
RefSeq	NP_542860.1. NC_003350.1.
3D structure databases
ProteinModelPortal	P49155.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1218750.
Phylogenomic databases
ProtClustDB	CLSK899100.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-12752.
UniPathway	UPA00273.
Family and domain databases
Gene3D	3.90.850.10. 1 hit.
InterPro	IPR017630. 4-oxalocrotonate_decarboxylase. IPR002529. Fumarylacetoacetase_C. IPR011234. Fumarylacetoacetase_C-rel. [Graphical view]
Pfam	PF01557. FAA_hydrolase. 1 hit. [Graphical view]
SUPFAM	SSF56529. Fumarylacetoacetase_C-rel. 1 hit.
TIGRFAMs	TIGR03218. catechol_dmpH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

XYLI_PSEPU

Accession

Primary (citable) accession number: P49155

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program