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P49155 (XYLI_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
4-oxalocrotonate decarboxylase

Short name=4-OD
EC=4.1.1.77
Gene names
Name:xylI
Encoded onPlasmid TOL pWW0
OrganismPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifier303 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(3E)-2-oxohex-3-enedioate = 2-oxopent-4-enoate + CO2.

Pathway

Xenobiotic degradation; toluene degradation.

Sequence similarities

Belongs to the hydratase/decarboxylase family.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   Molecular functionLyase
   Technical termPlasmid
Gene Ontology (GO)
   Biological_processtoluene catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_function4-oxalocrotonate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2642644-oxalocrotonate decarboxylase
PRO_0000066054

Sequences

Sequence LengthMass (Da)Tools
P49155 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: DDF93ACC910722F9

FASTA26428,510
        10         20         30         40         50         60 
MNRTLNREQV LALAEHIENA ELQAHDIHKV TNDYPEMTFA DAYTIQWEIR RRKEERGNKI 

        70         80         90        100        110        120 
VGLKMGLTSW AKMAQMGVET PIYGFLADYF SVPDGGVVDC SKLIHPKIEA EIAVVTKAPL 

       130        140        150        160        170        180 
VGPGCHIGDV IAAVDYVIPT VEVIDSRYEN FKFDLISVVA DNASSTRYIT GGRMANLEDV 

       190        200        210        220        230        240 
DLRTLGVVME KNGEVVELGA GAAVLGHPLS SVAMLANLLA ERGEHIPAGT FIMTGGITAA 

       250        260 
VAVAPGDNIT VRYQGLGSVS ARFV 

« Hide

References

[1]"Comparison of the nucleotide sequences of the meta-cleavage pathway genes of TOL plasmid pWW0 from Pseudomonas putida with other meta-cleavage genes suggests that both single and multiple nucleotide substitutions contribute to enzyme evolution."
Harayama S., Rekik M.
Mol. Gen. Genet. 239:81-89(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 33015 / DSM 3931 / JCM 6156 / NCIMB 12182 / mt-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M94186 Genomic DNA. Translation: AAA25693.1.
PIRS35224.
RefSeqNP_542860.1. NC_003350.1.

3D structure databases

ProteinModelPortalP49155.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1218750.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-12752.
UniPathwayUPA00273.

Family and domain databases

Gene3D3.90.850.10. 1 hit.
InterProIPR017630. 4-oxalocrotonate_decarboxylase.
IPR002529. Fumarylacetoacetase_C.
IPR011234. Fumarylacetoacetase_C-rel.
[Graphical view]
PfamPF01557. FAA_hydrolase. 1 hit.
[Graphical view]
SUPFAMSSF56529. SSF56529. 1 hit.
TIGRFAMsTIGR03218. catechol_dmpH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXYLI_PSEPU
AccessionPrimary (citable) accession number: P49155
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways