Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Malate synthase, glyoxysomal

Gene

LIP

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei173 – 1731Proton acceptorBy similarity
Active sitei459 – 4591Proton donorBy similarity

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-UniPathway
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase, glyoxysomal (EC:2.3.3.9)
Gene namesi
Name:LIP
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea
ProteomesiUP000007305: Unplaced

Organism-specific databases

GrameneiP49081.
MaizeGDBi100137.

Subcellular locationi

GO - Cellular componenti

  1. glyoxysome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Glyoxysome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 559559Malate synthase, glyoxysomalPRO_0000166870Add
BLAST

Proteomic databases

PRIDEiP49081.

Structurei

3D structure databases

ProteinModelPortaliP49081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi557 – 5593Microbody targeting signalSequence Analysis

Sequence similaritiesi

Belongs to the malate synthase family.Curated

Phylogenomic databases

HOGENOMiHOG000238464.
KOiK01638.

Family and domain databases

InterProiIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF001363. Malate_synth. 1 hit.
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P49081-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAASTAAPCY DAPEGVDVRG RYDREFAGIL TRDALDFVAG LQREFRGAVR
60 70 80 90 100
YAMEQRREAQ RRYDAGELPR FDPATTLVRE GDWTCASVPP AVADRTVEIT
110 120 130 140 150
GPAEPRKMVI NALNSGAKVF MADFEDAMSP TWENLMHGQV NLRDAVAGTI
160 170 180 190 200
SFRDAPRGRT YELNDRTAKL FVRPRGWHLP EAHILIDGEP AIGCLVDFGL
210 220 230 240 250
YFFHNHAAFG AGQGAGFGPL CDLPKMEHSR EARIWNGVFQ RAEKAAGIEP
260 270 280 290 300
GSIRATVLVE TLPAVFQMNE ILHELREHSA GLNCGRWDYI FSYVKTFRAH
310 320 330 340 350
PDRLLPDRAL VGMAQHFMRS YSHLLIHTCH RRGVHAMGGM AAQIPIKDDA
360 370 380 390 400
AANEAALELV RKDKLREVRA GHDGTWAAHP GLIPAIREVF EGHLGGRPNQ
410 420 430 440 450
IGDAAGHEGA SVKEEDLIQP PRGARTVDGL RLNVRVGVQY LAAWLAGSGS
460 470 480 490 500
VPLYNLMEDA ATAEISRVQN WQWLRHGAAL DAGGVEVRAT PELLARVVEE
510 520 530 540 550
EMARVEAEVG PDRFRKGRYA EAGRIFSRQC TAPELDDFLT LDAYNLIVAH

HPGASPCKL
Length:559
Mass (Da):61,637
Last modified:February 1, 1996 - v1
Checksum:iBC639B38D57C530B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35914 mRNA. Translation: AAB04118.1.
PIRiT03412.
RefSeqiNP_001105328.1. NM_001111858.1.
UniGeneiZm.66722.

Genome annotation databases

GeneIDi542252.
KEGGizma:542252.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35914 mRNA. Translation: AAB04118.1.
PIRiT03412.
RefSeqiNP_001105328.1. NM_001111858.1.
UniGeneiZm.66722.

3D structure databases

ProteinModelPortaliP49081.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP49081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi542252.
KEGGizma:542252.

Organism-specific databases

GrameneiP49081.
MaizeGDBi100137.

Phylogenomic databases

HOGENOMiHOG000238464.
KOiK01638.

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Family and domain databases

InterProiIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF001363. Malate_synth. 1 hit.
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequence of malate synthase cDNA in maize."
    Paek N.C., Taylor B.H., Smith J.D.
    Plant Gene Register PGR95-015
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Texas 5855.
    Tissue: Scutellum.

Entry informationi

Entry nameiMASY_MAIZE
AccessioniPrimary (citable) accession number: P49081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 4, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.