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P49079 (AKH1_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic
Short name=AK-HD 1
Short name=AK-HSDH 1

Including the following 2 domains:

  1. Aspartokinase
    EC=2.7.2.4
  2. Homoserine dehydrogenase
    EC=1.1.1.3
Gene names
Name:AKHSDH1
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogoneae › Zea

Protein attributes

Sequence length920 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 9292Chloroplast Potential
Chain93 – 920828Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic
PRO_0000002392

Regions

Domain412 – 48069ACT 1
Domain496 – 56368ACT 2
Nucleotide binding568 – 5736NADP Potential
Region93 – 341249Aspartokinase
Region342 – 566225Interface
Region567 – 920354Homoserine dehydrogenase

Sequences

Sequence LengthMass (Da)Tools
P49079 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 08DCF444BE645529

FASTA920100,336
        10         20         30         40         50         60 
MRSLTVASRH PGAAFSTRRR PLLHPAAAGR DSTFQRCWRW EKTQDSSFGS SLRTSRLPRT 

        70         80         90        100        110        120 
VHGDILKNLL APTAGAVSVE QAEAIADLPK GDMWSVHKFG GTCMGTSERI HNVADIVLRD 

       130        140        150        160        170        180 
PSERKLVVVS AMSKVTDMMY NLVNKAQSRD DSYIAVLDEV FDKHMTTAKD LLAGEDLARF 

       190        200        210        220        230        240 
LSQLHADISN LKAMLRAIYI AGHATESFSD FVVGHGELWS AQMLSYAIQK SGTPCSWMDT 

       250        260        270        280        290        300 
REVLVVNPSG ANQVDPDYLE SEKRLEKWFS RCPAETIIAT GFIASTPENI PTTLKRDGSD 

       310        320        330        340        350        360 
FSAAIIGSLV KARQVTIWTD VDGVFSADPR KVSEAVILST LSYQEAWEMS YFGANVLHPR 

       370        380        390        400        410        420 
TIIPVMKYNI PIVIRNIFNT SAPGTMICQQ PANENGDLEA CVKAFATIDK LALVNVEGTG 

       430        440        450        460        470        480 
MAGVPGTANA IFGAVKDVGA NVIMISQASS EHSVCFAVPE KEVALVSAAL HARFREALAA 

       490        500        510        520        530        540 
GRLSKVEVIH NCSILATVGL RMASTPGVSA TLFDALAKAN INVRAIAQGC SEYNITIVLK 

       550        560        570        580        590        600 
QEDCVRALRA AHSRFFLSKT TLAVGIIGPG LIGRTLLNQL KDQAAVLKEN MNIDLRVMGI 

       610        620        630        640        650        660 
AGSRTMLLSD IGVDLTQWKE KLQTEAEPAN LDKFVHHLSE NHFFPNRVLV DCTADTSVAS 

       670        680        690        700        710        720 
HYYDWLKKGI HVITPNKKAN SGPLDRYLKL RTLQRASYTH YFYEATVGAG LPIISTLRGL 

       730        740        750        760        770        780 
LETGDKILRI EGIFSGTLSY IFNNFEGART FSDVVAEAKK AGYTEPDPRD DLSGTDVARK 

       790        800        810        820        830        840 
VIILARESGL GLELSDIPVR SLVPEALKSC TSADEYMQKL PSFDEDWARE RKNAEAAGEV 

       850        860        870        880        890        900 
LRYVGVVDVV SKKGQVELRA YKRDHPFAQL SGSDNIIAFT TSRYKDQPLI VRGPGAGAEV 

       910        920 
TAGGVFCDIL RLSSYLGAPS

« Hide

References

[1]"Molecular genetics of the maize (Zea mays L.) aspartate kinase-homoserine dehydrogenase gene family."
Muehlbauer G.J., Somers D.A., Matthews B.F., Gengenbach B.G.
Plant Physiol. 106:1303-1312(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Seedling leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L33912 mRNA. Translation: AAA74360.1.
PIRT02953.
RefSeqNP_001105325.1. NM_001111855.1.
UniGeneZm.91735.

3D structure databases

ProteinModelPortalP49079.
ModBaseSearch...

Proteomic databases

PRIDEP49079.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID542249.
KEGGzma:542249.

Organism-specific databases

GrameneP49079.
MaizeGDB66609.

Phylogenomic databases

KOK12524.

Enzyme and pathway databases

UniPathwayUPA00034; UER00015.
UPA00050; UER00063.
UPA00050; UER00461.
UPA00051; UER00462.
UPA00051; UER00465.

Family and domain databases

Gene3D3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProIPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00696. AA_kinase. 1 hit.
PF01842. ACT. 2 hits.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
TIGRFAMsTIGR00657. asp_kinases. 1 hit.
PROSITEPS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAKH1_MAIZE
AccessionPrimary (citable) accession number: P49079
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 3, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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