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P49010

- HEXC_BOMMO

UniProt

P49010 - HEXC_BOMMO

Protein

Chitooligosaccharidolytic beta-N-acetylglucosaminidase

Gene
N/A
Organism
Bombyx mori (Silk moth)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Active during metamorphosis to degrade chitin.

    Catalytic activityi

    Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

    GO - Molecular functioni

    1. beta-N-acetylhexosaminidase activity Source: UniProtKB

    GO - Biological processi

    1. chitin catabolic process Source: UniProtKB
    2. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH20. Glycoside Hydrolase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chitooligosaccharidolytic beta-N-acetylglucosaminidase (EC:3.2.1.52)
    Alternative name(s):
    Beta-GlcNAcase
    Beta-N-acetylhexosaminidase
    Beta-hexosaminidase
    OrganismiBombyx mori (Silk moth)
    Taxonomic identifieri7091 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
    ProteomesiUP000005204: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 596573Chitooligosaccharidolytic beta-N-acetylglucosaminidasePRO_0000012013Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi166 – 1661N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi264 – 2641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi377 – 3771N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliP49010.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 20 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    KOiK12373.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProiIPR025705. Beta_hexosaminidase_sua/sub.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR029019. HEX_eukaryotic_N.
    [Graphical view]
    PfamiPF00728. Glyco_hydro_20. 1 hit.
    PF14845. Glycohydro_20b2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
    PRINTSiPR00738. GLHYDRLASE20.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF55545. SSF55545. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P49010-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWLQAICIYT VFIIIGCGIP TAAEEHSLWR WTCENNRCTK IRNEPENKEP    50
    VLSLEACKMF CDDYGLLWPK PTIETNLGNF LSKINMNTID IQITKQGKSD 100
    DLLTAAADRF KTLVSSSVPK GFSAKAAGKS VTVYLVNENP YIREFSLDMD 150
    ESYELYISST SSDKVNATIR GNSFFGVRNG LETLSQLIVY DDIRNNLLIV 200
    RDVTIKDRPV YPYRGILLDT ARNFYSIDSI KRTIDAMAAV KLNTFHWHIT 250
    DSQSFPLVLQ KRPNLSKLGA YSPTKVYTKQ DIREVVEYGL ERGVRVLPEF 300
    DAPAHVGEGW QDTGLTVCFK AEPWTKFCVE PPCGQLNPTK EELYDYLEDI 350
    YVEMAEAFES TDMFHMGGDE VSERCWNSSE EIQNFMIQNR WNLDKSSFLK 400
    LWNYFQKNAQ DRAYKAFGKR LPLILWTSTL TDYTHVEKFL DKDEYIIQVW 450
    TTGADPQIQG LLQKGYRLIM SNYDALYFDC GFGAWVGSGN NWCSPYIGGQ 500
    KVYGNSPAVM ALSYRDQILG GEVALWSEQS DPATLDGRLW PRAAAFAERM 550
    WAEPSTAWQD AEHRMLHVRE RLVRMGIQAE SLEPEWCYQN QGLCYG 596
    Length:596
    Mass (Da):68,213
    Last modified:February 1, 1996 - v1
    Checksum:iF302963E94A3A2FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S77548 mRNA. Translation: AAC60521.1.
    PIRiJC2539.
    RefSeqiNP_001037466.1. NM_001044001.1.
    UniGeneiBmo.345.

    Genome annotation databases

    GeneIDi693032.
    KEGGibmor:693032.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S77548 mRNA. Translation: AAC60521.1 .
    PIRi JC2539.
    RefSeqi NP_001037466.1. NM_001044001.1.
    UniGenei Bmo.345.

    3D structure databases

    ProteinModelPortali P49010.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH20. Glycoside Hydrolase Family 20.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 693032.
    KEGGi bmor:693032.

    Phylogenomic databases

    KOi K12373.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProi IPR025705. Beta_hexosaminidase_sua/sub.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR029019. HEX_eukaryotic_N.
    [Graphical view ]
    Pfami PF00728. Glyco_hydro_20. 1 hit.
    PF14845. Glycohydro_20b2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
    PRINTSi PR00738. GLHYDRLASE20.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF55545. SSF55545. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Purification of a chitooligosaccharidolytic beta-N-acetylglucosaminidase from Bombyx mori larvae during metamorphosis and the nucleotide sequence of its cDNA."
      Nagamatsu Y., Yanagisawa I., Kimoto M., Okamoto E., Koga D.
      Biosci. Biotechnol. Biochem. 59:219-225(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
      Strain: Kinshu X Showa.

    Entry informationi

    Entry nameiHEXC_BOMMO
    AccessioniPrimary (citable) accession number: P49010
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3