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P49010 (HEXC_BOMMO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chitooligosaccharidolytic beta-N-acetylglucosaminidase

EC=3.2.1.52
Alternative name(s):
Beta-GlcNAcase
Beta-N-acetylhexosaminidase
Beta-hexosaminidase
OrganismBombyx mori (Silk moth) [Reference proteome]
Taxonomic identifier7091 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx

Protein attributes

Sequence length596 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Active during metamorphosis to degrade chitin.

Catalytic activity

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Sequence similarities

Belongs to the glycosyl hydrolase 20 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 596573Chitooligosaccharidolytic beta-N-acetylglucosaminidase
PRO_0000012013

Amino acid modifications

Glycosylation1661N-linked (GlcNAc...) Potential
Glycosylation2641N-linked (GlcNAc...) Potential
Glycosylation3771N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P49010 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: F302963E94A3A2FF

FASTA59668,213
        10         20         30         40         50         60 
MWLQAICIYT VFIIIGCGIP TAAEEHSLWR WTCENNRCTK IRNEPENKEP VLSLEACKMF 

        70         80         90        100        110        120 
CDDYGLLWPK PTIETNLGNF LSKINMNTID IQITKQGKSD DLLTAAADRF KTLVSSSVPK 

       130        140        150        160        170        180 
GFSAKAAGKS VTVYLVNENP YIREFSLDMD ESYELYISST SSDKVNATIR GNSFFGVRNG 

       190        200        210        220        230        240 
LETLSQLIVY DDIRNNLLIV RDVTIKDRPV YPYRGILLDT ARNFYSIDSI KRTIDAMAAV 

       250        260        270        280        290        300 
KLNTFHWHIT DSQSFPLVLQ KRPNLSKLGA YSPTKVYTKQ DIREVVEYGL ERGVRVLPEF 

       310        320        330        340        350        360 
DAPAHVGEGW QDTGLTVCFK AEPWTKFCVE PPCGQLNPTK EELYDYLEDI YVEMAEAFES 

       370        380        390        400        410        420 
TDMFHMGGDE VSERCWNSSE EIQNFMIQNR WNLDKSSFLK LWNYFQKNAQ DRAYKAFGKR 

       430        440        450        460        470        480 
LPLILWTSTL TDYTHVEKFL DKDEYIIQVW TTGADPQIQG LLQKGYRLIM SNYDALYFDC 

       490        500        510        520        530        540 
GFGAWVGSGN NWCSPYIGGQ KVYGNSPAVM ALSYRDQILG GEVALWSEQS DPATLDGRLW 

       550        560        570        580        590 
PRAAAFAERM WAEPSTAWQD AEHRMLHVRE RLVRMGIQAE SLEPEWCYQN QGLCYG 

« Hide

References

[1]"Purification of a chitooligosaccharidolytic beta-N-acetylglucosaminidase from Bombyx mori larvae during metamorphosis and the nucleotide sequence of its cDNA."
Nagamatsu Y., Yanagisawa I., Kimoto M., Okamoto E., Koga D.
Biosci. Biotechnol. Biochem. 59:219-225(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
Strain: Kinshu X Showa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S77548 mRNA. Translation: AAC60521.1.
PIRJC2539.
RefSeqNP_001037466.1. NM_001044001.1.
UniGeneBmo.345.

3D structure databases

ProteinModelPortalP49010.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH20. Glycoside Hydrolase Family 20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID693032.
KEGGbmor:693032.

Phylogenomic databases

KOK12373.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR025705. Beta_hexosaminidase_sua/sub.
IPR015883. Glyco_hydro_20_cat-core.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00728. Glyco_hydro_20. 1 hit.
[Graphical view]
PIRSFPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
PRINTSPR00738. GLHYDRLASE20.
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHEXC_BOMMO
AccessionPrimary (citable) accession number: P49010
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: December 11, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries