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P49007

- HEXB_PSEO7

UniProt

P49007 - HEXB_PSEO7

Protein

Beta-hexosaminidase B

Gene

nag096

Organism
Pseudoalteromonas piscicida
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei531 – 5311Proton donorBy similarity

    GO - Molecular functioni

    1. beta-N-acetylhexosaminidase activity Source: UniProtKB-EC
    2. polysaccharide binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Protein family/group databases

    CAZyiGH20. Glycoside Hydrolase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-hexosaminidase B (EC:3.2.1.52)
    Alternative name(s):
    Beta-GlcNAcase
    Beta-N-acetylhexosaminidase
    Short name:
    Beta-NAHase
    N-acetyl-beta-glucosaminidase
    Gene namesi
    Name:nag096
    OrganismiPseudoalteromonas piscicida
    Taxonomic identifieri43662 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 773754Beta-hexosaminidase BPRO_0000012015Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi46 ↔ 53By similarity
    Disulfide bondi389 ↔ 397By similarity
    Disulfide bondi496 ↔ 542By similarity

    Keywords - PTMi

    Disulfide bond

    Structurei

    3D structure databases

    ProteinModelPortaliP49007.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 20 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.40.290. 1 hit.
    3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProiIPR025705. Beta_hexosaminidase_sua/sub.
    IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR004866. CHB/HEX_N_dom.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR015882. HEX_bac_N.
    [Graphical view]
    PfamiPF03173. CHB_HEX. 1 hit.
    PF00728. Glyco_hydro_20. 1 hit.
    PF02838. Glyco_hydro_20b. 1 hit.
    [Graphical view]
    PRINTSiPR00738. GLHYDRLASE20.
    SMARTiSM01081. CHB_HEX. 1 hit.
    [Graphical view]
    SUPFAMiSSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF55545. SSF55545. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P49007-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFNRLMALL FGVSSPLYAL DQTAVNWLGQ NLDVKYTLLD TKPTTCPKAQ    50
    QKCYYSELSF SVRKENTKAN NDFAIFFSQL MPIYHVEGDN FAITHINGDI 100
    HKITPAAGFS GFSSAPTTVR FYTKDSQVTR SEVYAKLCCE RTRSLKLTPQ 150
    VIKSTQTQRD NDTGLDCNLN LTPFVTLNQL QTSSKDDTPW MGSEYLYQHQ 200
    VKPTLDAAIG LIPKPKQLTV LSDKRLNLAA GINLQLSGIS ADAIAMAQQR 250
    LNTLGVKSTK EGLVVNVAVK PNKQSSPHYQ LTVAENNISI QGNNSAAAFY 300
    ALQSLAGLLD INDLRIPMVD IIDTPRYDFR GLHVDVARNF RSKAFILQTI 350
    EQMAAYKLNK LHLHLADDEG WRLAIDGLDE LTSVGAYRCF DLTETRCLLP 400
    QLGAGNDKNA QVNGFYSAED YIEILRYAKA HHIEVLPSLD MPGHSRAAII 450
    AMEARYKKLM AQGKPEDAQK YRLVETADKT RYSSIQHYND NTLNVCIANT 500
    YTFIDKVLSE VKVLHDRAGV PLNTYHIGAD ETAVLWLESP ACKKLQASVK 550
    DFTNFNGYFI ERVAKLLDKK GIQVAGWSDG LGDVRAANMP ANIQSNGLGD 600
    IKRKRAPVAH RFANQGWQVV LSSPDVTYFD FPYQSHPEER GNHWASRAIE 650
    SKKMFEFMPD NLPAHAEIWK NTNNHAYIAN DSDSSLNKGV QFAGLQGHLW 700
    SEMLRSDAQA EYMLYPRLLA LAERAWHHAE WELPYQAGRI YSQSSGYFTA 750
    KLQAQREADW QRFVAILGNS RTT 773
    Length:773
    Mass (Da):86,760
    Last modified:February 1, 1996 - v1
    Checksum:iDBB379885E004642
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D29665 Genomic DNA. Translation: BAA06136.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D29665 Genomic DNA. Translation: BAA06136.1 .

    3D structure databases

    ProteinModelPortali P49007.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH20. Glycoside Hydrolase Family 20.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.40.290. 1 hit.
    3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProi IPR025705. Beta_hexosaminidase_sua/sub.
    IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR004866. CHB/HEX_N_dom.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR015882. HEX_bac_N.
    [Graphical view ]
    Pfami PF03173. CHB_HEX. 1 hit.
    PF00728. Glyco_hydro_20. 1 hit.
    PF02838. Glyco_hydro_20b. 1 hit.
    [Graphical view ]
    PRINTSi PR00738. GLHYDRLASE20.
    SMARTi SM01081. CHB_HEX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF55545. SSF55545. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of the gene which encodes beta-N-acetylglucosaminidase from a marine bacterium, Alteromonas sp. strain O-7."
      Tsujibo H., Fujimoto K., Tanno H., Miyamoto K., Kimura Y., Imada C., Okami Y., Inamori Y.
      Appl. Environ. Microbiol. 61:804-806(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: O-7.

    Entry informationi

    Entry nameiHEXB_PSEO7
    AccessioniPrimary (citable) accession number: P49007
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3