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P49007

- HEXB_PSEO7

UniProt

P49007 - HEXB_PSEO7

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Protein

Beta-hexosaminidase B

Gene

nag096

Organism
Pseudoalteromonas piscicida
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei531 – 5311Proton donorBy similarity

GO - Molecular functioni

  1. beta-N-acetylhexosaminidase activity Source: UniProtKB-EC
  2. polysaccharide binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH20. Glycoside Hydrolase Family 20.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidase B (EC:3.2.1.52)
Alternative name(s):
Beta-GlcNAcase
Beta-N-acetylhexosaminidase
Short name:
Beta-NAHase
N-acetyl-beta-glucosaminidase
Gene namesi
Name:nag096
OrganismiPseudoalteromonas piscicida
Taxonomic identifieri43662 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 773754Beta-hexosaminidase BPRO_0000012015Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi46 ↔ 53By similarity
Disulfide bondi389 ↔ 397By similarity
Disulfide bondi496 ↔ 542By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP49007.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 20 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.290. 1 hit.
3.20.20.80. 1 hit.
3.30.379.10. 1 hit.
InterProiIPR025705. Beta_hexosaminidase_sua/sub.
IPR008965. Carb-bd_dom.
IPR012291. CBD_carb-bd_dom.
IPR004866. CHB/HEX_N_dom.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat-core.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR015882. HEX_bac_N.
[Graphical view]
PfamiPF03173. CHB_HEX. 1 hit.
PF00728. Glyco_hydro_20. 1 hit.
PF02838. Glyco_hydro_20b. 1 hit.
[Graphical view]
PRINTSiPR00738. GLHYDRLASE20.
SMARTiSM01081. CHB_HEX. 1 hit.
[Graphical view]
SUPFAMiSSF49384. SSF49384. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P49007-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKFNRLMALL FGVSSPLYAL DQTAVNWLGQ NLDVKYTLLD TKPTTCPKAQ
60 70 80 90 100
QKCYYSELSF SVRKENTKAN NDFAIFFSQL MPIYHVEGDN FAITHINGDI
110 120 130 140 150
HKITPAAGFS GFSSAPTTVR FYTKDSQVTR SEVYAKLCCE RTRSLKLTPQ
160 170 180 190 200
VIKSTQTQRD NDTGLDCNLN LTPFVTLNQL QTSSKDDTPW MGSEYLYQHQ
210 220 230 240 250
VKPTLDAAIG LIPKPKQLTV LSDKRLNLAA GINLQLSGIS ADAIAMAQQR
260 270 280 290 300
LNTLGVKSTK EGLVVNVAVK PNKQSSPHYQ LTVAENNISI QGNNSAAAFY
310 320 330 340 350
ALQSLAGLLD INDLRIPMVD IIDTPRYDFR GLHVDVARNF RSKAFILQTI
360 370 380 390 400
EQMAAYKLNK LHLHLADDEG WRLAIDGLDE LTSVGAYRCF DLTETRCLLP
410 420 430 440 450
QLGAGNDKNA QVNGFYSAED YIEILRYAKA HHIEVLPSLD MPGHSRAAII
460 470 480 490 500
AMEARYKKLM AQGKPEDAQK YRLVETADKT RYSSIQHYND NTLNVCIANT
510 520 530 540 550
YTFIDKVLSE VKVLHDRAGV PLNTYHIGAD ETAVLWLESP ACKKLQASVK
560 570 580 590 600
DFTNFNGYFI ERVAKLLDKK GIQVAGWSDG LGDVRAANMP ANIQSNGLGD
610 620 630 640 650
IKRKRAPVAH RFANQGWQVV LSSPDVTYFD FPYQSHPEER GNHWASRAIE
660 670 680 690 700
SKKMFEFMPD NLPAHAEIWK NTNNHAYIAN DSDSSLNKGV QFAGLQGHLW
710 720 730 740 750
SEMLRSDAQA EYMLYPRLLA LAERAWHHAE WELPYQAGRI YSQSSGYFTA
760 770
KLQAQREADW QRFVAILGNS RTT
Length:773
Mass (Da):86,760
Last modified:February 1, 1996 - v1
Checksum:iDBB379885E004642
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D29665 Genomic DNA. Translation: BAA06136.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D29665 Genomic DNA. Translation: BAA06136.1 .

3D structure databases

ProteinModelPortali P49007.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH20. Glycoside Hydrolase Family 20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.40.290. 1 hit.
3.20.20.80. 1 hit.
3.30.379.10. 1 hit.
InterProi IPR025705. Beta_hexosaminidase_sua/sub.
IPR008965. Carb-bd_dom.
IPR012291. CBD_carb-bd_dom.
IPR004866. CHB/HEX_N_dom.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat-core.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR015882. HEX_bac_N.
[Graphical view ]
Pfami PF03173. CHB_HEX. 1 hit.
PF00728. Glyco_hydro_20. 1 hit.
PF02838. Glyco_hydro_20b. 1 hit.
[Graphical view ]
PRINTSi PR00738. GLHYDRLASE20.
SMARTi SM01081. CHB_HEX. 1 hit.
[Graphical view ]
SUPFAMi SSF49384. SSF49384. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of the gene which encodes beta-N-acetylglucosaminidase from a marine bacterium, Alteromonas sp. strain O-7."
    Tsujibo H., Fujimoto K., Tanno H., Miyamoto K., Kimura Y., Imada C., Okami Y., Inamori Y.
    Appl. Environ. Microbiol. 61:804-806(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: O-7.

Entry informationi

Entry nameiHEXB_PSEO7
AccessioniPrimary (citable) accession number: P49007
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 1, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3