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Protein

Transaldolase 2

Gene

tal2

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.By similarity

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase 2 (tal2), Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141Schiff-base intermediate with substrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Transaldolase 2 (EC:2.2.1.2)
Gene namesi
Name:tal2
Ordered Locus Names:all4020
OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001736281 – 381Transaldolase 2Add BLAST381

Interactioni

Protein-protein interaction databases

STRINGi103690.all4020

Structurei

3D structure databases

ProteinModelPortaliP48993
SMRiP48993
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 2 subfamily.Curated

Phylogenomic databases

eggNOGiENOG4107QQX Bacteria
COG0176 LUCA
HOGENOMiHOG000226074
KOiK00616
OMAiATECYYQ
OrthoDBiPOG091H05PS

Family and domain databases

CDDicd00955 Transaldolase_like, 1 hit
Gene3Di3.20.20.701 hit
HAMAPiMF_00493 Transaldolase_2, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004732 Transaldolase_2
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF19 PTHR10683:SF19, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
PIRSFiPIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsiTIGR00876 tal_mycobact, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P48993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAINHLLEIK EYGQSIWMDN LSRDIIQSGE LKNLVENQGI CGITSNPAIF
60 70 80 90 100
EKAIANNVIY DADIEAGVRA GLPTYKIYES LIFADIRNAC DILRPVYEAS
110 120 130 140 150
NKLDGYVSIE VPPTIAHDTQ ATINEARRYY QEIGRENVMI KIPGTEAGLP
160 170 180 190 200
AVEQVIAEGI NVNVTLLFSV QSYINTIWAY IRGLEKRLAE GKDISQIASV
210 220 230 240 250
ASFFLSRIDI NIDGKIDAKL ARGVDDISLE AKLMVVKGKV AIANAKIAYQ
260 270 280 290 300
EYKKIIESDQ WQALAAKGAK VQRLLWASTS TKDPNYSDVM YVDELIGPDT
310 320 330 340 350
VNTLPPATIT ACADHCEVAN RVETGVAEAY QLIESLKDPD INIDINAVMD
360 370 380
ELLIEGINKF VQPFQSLMNS LEGKVKLLSP V
Length:381
Mass (Da):42,023
Last modified:January 23, 2002 - v2
Checksum:i1A016AD8B486311A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15 – 16SI → MY in AAA98852 (PubMed:8566707).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33282 Genomic DNA Translation: AAA98852.1
BA000019 Genomic DNA Translation: BAB75719.1
PIRiAE2308
RefSeqiWP_010998160.1, NC_003272.1

Genome annotation databases

EnsemblBacteriaiBAB75719; BAB75719; BAB75719
KEGGiana:all4020

Similar proteinsi

Entry informationi

Entry nameiTAL2_NOSS1
AccessioniPrimary (citable) accession number: P48993
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2002
Last modified: October 25, 2017
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome