P48983 (TAL2_NOSP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase 2
EC=2.2.1.2

Gene names

Name:	tal2
Ordered Locus Names:	Npun_F4024

Organism

Nostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]

Taxonomic identifier

63737 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. HAMAP MF_00493
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00493
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00493
Subcellular location	Cytoplasm By similarity HAMAP MF_00493.
Sequence similarities	Belongs to the transaldolase family. Type 2 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Transaldolase 2 HAMAP MF_00493		PRO_0000173629
Sites
	Active site	141	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P48983 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 906E28CDE77755F9	FASTA	381	42,303
	10 20 30 40 50 60 MSTNHLLEIK QYGQSIWMDN LTRDIIQSGE LKDMVENQGI SGITSNPAIF EKAIAGNAIY 70 80 90 100 110 120 DADIEAGVRA GLPIYKIYES LVFADIRNAC DILRPVYEAS NRLDGYVSIE VPPTIAHDTE 130 140 150 160 170 180 ATISEARRYF QEIGRENLMI KIPGTEPGLP AVEQVIAEGM NVNITLLFSV ESYVNTAWAY 190 200 210 220 230 240 VRGLEKRLAE GKDISRIASV ASFFLSRIDS NIDAKIDAKL KKGVDDIAVE AKLKAVKGKV 250 260 270 280 290 300 AIANAKLAYQ EYKKIIRSER WQELVAKGAT VQRLLWASTS TKDPNYNDVM YIEELVGPDT 310 320 330 340 350 360 VNTVPPATIK ACADHCNVSD RLETDVNNAY TLIENLKDPD INIDLDTVMD ELLVEGIDKF 370 380 IQPFQSLMNS LEDKIKVLSP V

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of an operon in Nostoc sp. strain ATCC 29133 encoding four genes of the oxidative pentose phosphate cycle." Summers M.L., Meeks J.C., Chu S., Wolf R.E. Jr. Plant Physiol. 107:267-268(1995) [PubMed: 7870816] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29133 / PCC 73102.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L32796 Genomic DNA. Translation: AAA50769.1. CP001037 Genomic DNA. Translation: ACC82403.1.
RefSeq	YP_001867346.1. NC_010628.1.
3D structure databases
ProteinModelPortal	P48983.
ModBase	Search...
Protein-protein interaction databases
STRING	P48983.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6253369.
GenomeReviews	Gene locus Npun_F4024 in contig CP001037_GR.
KEGG	npu:Npun_F4024.
PATRIC	22761128. VBINosPun48114_4723.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG321149.
OMA	MPEKTLD.
PhylomeDB	P48983.
ProtClustDB	PRK03343.
Family and domain databases
HAMAP	MF_00493. Transaldolase_2. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004732. Transaldolase_2. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
PIRSF	PIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMs	TIGR00876. Tal_mycobact. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL2_NOSP7

Accession

Primary (citable) accession number: P48983
Secondary accession number(s): B2J6J8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program