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P48952 (RL3_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L3
Gene names
Name:rplC
Ordered Locus Names:RP659
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length216 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP-Rule MF_01325

Subunit structure

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19 By similarity.

Post-translational modification

Methylated by PrmB By similarity. HAMAP-Rule MF_01325

Sequence similarities

Belongs to the ribosomal protein L3P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMMethylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 21621650S ribosomal protein L3 HAMAP-Rule MF_01325
PRO_0000077147

Amino acid modifications

Modified residue1511N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
P48952 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 10F07EEFB39C287D

FASTA21623,652
        10         20         30         40         50         60 
MRTGIIAQKV GMTSVFNDKG ERISLTLVKV DDCQVVGHKT LAKHGYNALV IGVKDQKISK 

        70         80         90        100        110        120 
VTKPMKQVFA NAKIAPKTKL KEFRISEDNF IDIASILEVD HFRVGQFVDI TATTIGKGFA 

       130        140        150        160        170        180 
GSMKRHNFRG LEASHGVSIS HRSHGSTGQR QDPGKVFKGK KMAGHMGCNK VTIQNLKIFA 

       190        200        210 
VDTNRKLIMI QGSIPGHKNS YLLVKDAIKK AAITIA 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.
[2]"A chimeric disposition of the elongation factor genes in Rickettsia prowazekii."
Syvaenen A.-C., Amiri H., Jamal A., Andersson S.G.E., Kurland C.G.
J. Bacteriol. 178:6192-6199(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-23.
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235272 Genomic DNA. Translation: CAA15099.1.
Z54170 Genomic DNA. Translation: CAA90883.1.
PIRA71672.
RefSeqNP_221023.1. NC_000963.1.

3D structure databases

ProteinModelPortalP48952.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP659.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15099; CAA15099; CAA15099.
GeneID883884.
KEGGrpr:RP659.
PATRIC17902145. VBIRicPro72556_0681.

Phylogenomic databases

eggNOGCOG0087.
HOGENOMHOG000100368.
KOK02906.
OMAKGMRMAG.
OrthoDBEOG6WDSMH.
ProtClustDBPRK00001.

Family and domain databases

HAMAPMF_01325_B. Ribosomal_L3_B.
InterProIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERPTHR11229. PTHR11229. 1 hit.
PfamPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMSSF50447. SSF50447. 1 hit.
TIGRFAMsTIGR03625. L3_bact. 1 hit.
PROSITEPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRL3_RICPR
AccessionPrimary (citable) accession number: P48952
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: May 30, 2000
Last modified: February 19, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names

Ribosomal proteins

Ribosomal proteins families and list of entries