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P48891

- COX3_ALBCA

UniProt

P48891 - COX3_ALBCA

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Protein
Cytochrome c oxidase subunit 3
Gene
COIII
Organism
Albinaria caerulea (Land snail)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiAlbinaria caerulea (Land snail)
Taxonomic identifieri42349 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraPanpulmonataEupulmonataStylommatophoraSigmurethraClausilioideaClausiliidaeAlopiinaeAlbinaria

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321Helical; Reviewed prediction
Add
BLAST
Transmembranei35 – 5521Helical; Reviewed prediction
Add
BLAST
Transmembranei80 – 10021Helical; Reviewed prediction
Add
BLAST
Transmembranei119 – 14123Helical; Reviewed prediction
Add
BLAST
Transmembranei154 – 17421Helical; Reviewed prediction
Add
BLAST
Transmembranei195 – 21521Helical; Reviewed prediction
Add
BLAST
Transmembranei232 – 25221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Cytochrome c oxidase subunit 3
PRO_0000183729Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP48891.
SMRiP48891. Positions 2-259.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48891-1 [UniParc]FASTAAdd to Basket

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MQKTPFHLVE YSPWPLLVSL SLTSMPLGLI YYIRFGSIYL LLYGMLLTSI    50
IAYMWWRDIV REATYQGHHT TYVVKGLKLG MALFILSEVC FFFAFFWAYF 100
HSSLAPSIEI GSVWPPIGIT VLNVFQVPLL NTSVLLLSGV SITWAHHALT 150
EGKYYSTLSG LFFTVLLGVY FLMLQYGEYN ETSFSIADGV YGSTFFMATG 200
FHGLHVMVGT LFLFVNLVRT YYYHFSTTHH VGFLAAAWYW HFVDVVWLFL 250
YISIYWWGS 259
Length:259
Mass (Da):29,875
Last modified:February 1, 1996 - v1
Checksum:i825369E846A6067B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83390 Genomic DNA. Translation: CAA58305.1.
PIRiS59152.
RefSeqiNP_007338.1. NC_001761.1.

Genome annotation databases

GeneIDi808003.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83390 Genomic DNA. Translation: CAA58305.1 .
PIRi S59152.
RefSeqi NP_007338.1. NC_001761.1.

3D structure databases

ProteinModelPortali P48891.
SMRi P48891. Positions 2-259.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 808003.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence and gene organization of the mitochondrial genome of the land snail Albinaria coerulea."
    Hatzoglou E., Rodakis G.C., Lecanidou R.
    Genetics 140:1353-1366(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_ALBCA
AccessioniPrimary (citable) accession number: P48891
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: September 3, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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