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P48891 (COX3_ALBCA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismAlbinaria caerulea (Land snail)
Taxonomic identifier42349 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraPanpulmonataEupulmonataStylommatophoraSigmurethraClausilioideaClausiliidaeAlopiinaeAlbinaria

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Cytochrome c oxidase subunit 3
PRO_0000183729

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane35 – 5521Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane119 – 14123Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane232 – 25221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P48891 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 825369E846A6067B

FASTA25929,875
        10         20         30         40         50         60 
MQKTPFHLVE YSPWPLLVSL SLTSMPLGLI YYIRFGSIYL LLYGMLLTSI IAYMWWRDIV 

        70         80         90        100        110        120 
REATYQGHHT TYVVKGLKLG MALFILSEVC FFFAFFWAYF HSSLAPSIEI GSVWPPIGIT 

       130        140        150        160        170        180 
VLNVFQVPLL NTSVLLLSGV SITWAHHALT EGKYYSTLSG LFFTVLLGVY FLMLQYGEYN 

       190        200        210        220        230        240 
ETSFSIADGV YGSTFFMATG FHGLHVMVGT LFLFVNLVRT YYYHFSTTHH VGFLAAAWYW 

       250 
HFVDVVWLFL YISIYWWGS 

« Hide

References

[1]"Complete sequence and gene organization of the mitochondrial genome of the land snail Albinaria coerulea."
Hatzoglou E., Rodakis G.C., Lecanidou R.
Genetics 140:1353-1366(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X83390 Genomic DNA. Translation: CAA58305.1.
PIRS59152.
RefSeqNP_007338.1. NC_001761.1.

3D structure databases

ProteinModelPortalP48891.
SMRP48891. Positions 2-259.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808003.

Organism-specific databases

CTD4514.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_ALBCA
AccessionPrimary (citable) accession number: P48891
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families