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P48874 (COX3_WICCA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Encoded onMitochondrion
OrganismWickerhamomyces canadensis (Yeast) (Pichia canadensis)
Taxonomic identifier1156965 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeWickerhamomyces

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183832

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane204 – 22421Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P48874 [UniParc].

Last modified August 30, 2002. Version 2.
Checksum: EA9311386322BE51

FASTA26930,467
        10         20         30         40         50         60 
MTHLERSRHQ LFPFHLVSPS PWPITVSFAL MSFALSLGLT MHGYIVGNSV LFTSIILVLY 

        70         80         90        100        110        120 
SMTMWFRDII AEGTYLGDHT LAVRKGLNYG FLLFVVSEIL IFAGIFWAYF HSAMSPAIEI 

       130        140        150        160        170        180 
GGVWPPVGIT AIGATELPLL NTIILLASGA TITYSHHATI EGNRNHALNG LFITLWLIVI 

       190        200        210        220        230        240 
FVVCQYIEYT NAPFTISDGV YGSVFFAGTG LHFLHMGMLI IMLAVCYWRM RQYHFTTGHH 

       250        260 
VNYETTILYL HVLDVIWLFL YIVMYWWGA 

« Hide

References

[1]"The complete mitochondrial DNA sequence of Hansenula wingei reveals new characteristics of yeast mitochondria."
Sekito T., Okamoto K., Kitano H., Yoshida K.
Curr. Genet. 28:39-53(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 21.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D31785 Genomic DNA. Translation: BAA06569.2.
PIRS58746.
RefSeqNP_038214.1. NC_001762.1.

3D structure databases

ProteinModelPortalP48874.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID800535.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_WICCA
AccessionPrimary (citable) accession number: P48874
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 30, 2002
Last modified: April 16, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families