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P48874

- COX3_WICCA

UniProt

P48874 - COX3_WICCA

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Protein

Cytochrome c oxidase subunit 3

Gene
COX3
Organism
Wickerhamomyces canadensis (Yeast) (Pichia canadensis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COX3
Encoded oniMitochondrion
OrganismiWickerhamomyces canadensis (Yeast) (Pichia canadensis)
Taxonomic identifieri1156965 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeWickerhamomyces

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121Helical; Reviewed predictionAdd
BLAST
Transmembranei45 – 6521Helical; Reviewed predictionAdd
BLAST
Transmembranei90 – 11021Helical; Reviewed predictionAdd
BLAST
Transmembranei127 – 14721Helical; Reviewed predictionAdd
BLAST
Transmembranei167 – 18721Helical; Reviewed predictionAdd
BLAST
Transmembranei204 – 22421Helical; Reviewed predictionAdd
BLAST
Transmembranei247 – 26721Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Cytochrome c oxidase subunit 3PRO_0000183832Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP48874.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48874-1 [UniParc]FASTAAdd to Basket

« Hide

MTHLERSRHQ LFPFHLVSPS PWPITVSFAL MSFALSLGLT MHGYIVGNSV    50
LFTSIILVLY SMTMWFRDII AEGTYLGDHT LAVRKGLNYG FLLFVVSEIL 100
IFAGIFWAYF HSAMSPAIEI GGVWPPVGIT AIGATELPLL NTIILLASGA 150
TITYSHHATI EGNRNHALNG LFITLWLIVI FVVCQYIEYT NAPFTISDGV 200
YGSVFFAGTG LHFLHMGMLI IMLAVCYWRM RQYHFTTGHH VNYETTILYL 250
HVLDVIWLFL YIVMYWWGA 269
Length:269
Mass (Da):30,467
Last modified:August 30, 2002 - v2
Checksum:iEA9311386322BE51
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D31785 Genomic DNA. Translation: BAA06569.2.
PIRiS58746.
RefSeqiNP_038214.1. NC_001762.1.

Genome annotation databases

GeneIDi800535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D31785 Genomic DNA. Translation: BAA06569.2 .
PIRi S58746.
RefSeqi NP_038214.1. NC_001762.1.

3D structure databases

ProteinModelPortali P48874.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 800535.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete mitochondrial DNA sequence of Hansenula wingei reveals new characteristics of yeast mitochondria."
    Sekito T., Okamoto K., Kitano H., Yoshida K.
    Curr. Genet. 28:39-53(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 21.

Entry informationi

Entry nameiCOX3_WICCA
AccessioniPrimary (citable) accession number: P48874
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 30, 2002
Last modified: September 3, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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