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P48873 (COX3_CYACA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Synonyms:COXIII
Encoded onMitochondrion
OrganismCyanidium caldarium
Taxonomic identifier2771 [NCBI]
Taxonomic lineageEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidium

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 270270Cytochrome c oxidase subunit 3
PRO_0000183761

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane131 – 15121Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane248 – 26821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P48873 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 52917FBDCAE953C5

FASTA27031,564
        10         20         30         40         50         60 
MMSLIVKDLQ RYPFHLVDPS PWPFVASFSA LIILLGGVLY FHTYQGSLVI LFFGIFFLLL 

        70         80         90        100        110        120 
IIFVWWRDVV RESTFEGNHT TMVQLGMRYG IMLFIFSEVI LFIAFFWAFF HNSLIPALET 

       130        140        150        160        170        180 
GVVWPPKGIQ FFSPWDIPFL NTIILLLSGC AVTWSHNCII SGFRRQAIFS LILTIGLALI 

       190        200        210        220        230        240 
FTIFQIYEYA IASFHLSDGA YGSTFFMITG LHGFHVIVGT FFLFVCMFRL VQYHFTMQHH 

       250        260        270 
YGFEAATWYW HFVDVVWLFL FVSIYWWGSF 

« Hide

References

[1]Viehmann S.
Thesis (1995), Justus Liebig University / Frankfurt, Germany
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: RK-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z48930 Genomic DNA. Translation: CAA88770.1.
PIRS62760.

3D structure databases

ProteinModelPortalP48873.
SMRP48873. Positions 10-269.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_CYACA
AccessionPrimary (citable) accession number: P48873
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families