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P48872 (COX3_CHOCR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Encoded onMitochondrion
OrganismChondrus crispus (Carragheen moss) (Irish moss)
Taxonomic identifier2769 [NCBI]
Taxonomic lineageEukaryotaRhodophytaFlorideophyceaeGigartinalesGigartinaceaeChondrus

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Cytochrome c oxidase subunit 3
PRO_0000183758

Regions

Transmembrane23 – 4321Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane169 – 18921Helical; Potential
Transmembrane210 – 23021Helical; Potential
Transmembrane249 – 26921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P48872 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: DC408B19950F4021

FASTA27231,189
        10         20         30         40         50         60 
MTTLSQISKS VQRHPFHLVD PSPWPFVASL CAFSCAIGGV MYMHAYVNGS FILSISFFCL 

        70         80         90        100        110        120 
LLVMFTWWRD VIRESTFEGH HTGIVQQGLR FGVILFIISE ILFFFAFFWA FFHSSLAPTI 

       130        140        150        160        170        180 
EIGSIWPPKG INVLNPWEIP FLNTLILLLS GCTVTWCHHS LVSNLRNQSV LSLFLTIVLA 

       190        200        210        220        230        240 
IVFTTFQAYE YSMADFRLSD GIYGSTFYMA TGFHGFHVLV GTISLAVCLI RLLQYQLTQQ 

       250        260        270 
HHFGFESAAW YWHFVDVVWL FLFVSIYWWG GS 

« Hide

References

[1]"Complete sequence of the mitochondrial DNA of the rhodophyte Chondrus crispus (Gigartinales). Gene content and genome organization."
Leblanc C., Boyen C., Richard O., Bonnard G., Grienenberger J.-M., Kloareg B.
J. Mol. Biol. 250:484-495(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Apices.
[2]"Nucleotide sequence of the cox3 gene from Chondrus crispus: evidence that UGA encodes tryptophan and evolutionary implications."
Boyen C., Leblanc C., Bonnard G., Grienenberger J.M., Kloareg B.
Nucleic Acids Res. 22:1400-1403(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Apices.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z47547 Genomic DNA. Translation: CAA87605.1.
PIRS43951.
RefSeqNP_062484.1. NC_001677.2.

3D structure databases

ProteinModelPortalP48872.
SMRP48872. Positions 11-271.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID809356.
KEGGccp:ChcroMp05.

Phylogenomic databases

KOK02262.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_CHOCR
AccessionPrimary (citable) accession number: P48872
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families