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Reviewed, UniProtKB/Swiss-Prot P48846 (CHIS_NOCSP)

Last modified June 16, 2009. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Chitosanase
    EC=3.2.1.132
Gene names
Name: csn
OrganismNocardioides sp. (strain N106)
Taxonomic identifier47919 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeNocardioides

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.

Catalytic activity

Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 46 family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchitosanase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 4141 Potential
Chain42 – 278237Chitosanase
PRO_0000012208

Sites

Active site631Proton donor By similarity
Active site811Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P48846-1 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: E76AA20065FAB4FF

FASTA27829,987
        10         20         30         40         50         60 
MRLKHPTARL ALAALLVAVP RSVAAAGTVH AAPAPAGATR LAAVGLDDPH KKDIAMQLVS 

        70         80         90        100        110        120 
SAENSSLDWK SQYKYIEDIK DGRGYTAGII GFCSGTGDML DLVADYTDLK PGNILAKYLP 

       130        140        150        160        170        180 
ALRKVNGTES HAGLASAFEK DWATAAKDSV FQQAQNDERD RSYFNPAVNQ AKASLRALGQ 

       190        200        210        220        230        240 
FAYYDAIVMH GPGDSSDSFG GIRKAAMKKA KTPAQGRDEA TYLKAFLAAR KTVMLKEEAH 

       250        260        270 
SDTSRVDTEQ TVFLNAKNFD LNPPLKWKVY GDSYAINS 

« Hide

References

[1]"A new chitosanase gene from a Nocardioides sp. is a third member of glycosyl hydrolase family 46."
Masson J.Y., Boucher I., Neugebauer W.A., Ramotar D., Brzezinski R.
Microbiology 141:2629-2635(1995) [PubMed: 7582023] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

L40408 Genomic DNA. Translation: AAA63405.1.

3D structure databases

HSSPHSSP built from PDB template 1CHK based on UniProtKB P33665.
SMRP48846. Positions 42-278.
ModBaseSearch...

Protein family/group databases

CAZyGH46. Glycoside Hydrolase Family 46.

Family and domain databases

InterProIPR000400. Glyco_hydro_46.
[Graphical view]
PfamPF01374. Glyco_hydro_46. 1 hit.
[Graphical view]
PIRSFPIRSF036551. Chitosanase. 1 hit.
PROSITEPS60000. CHITOSANASE_46_80. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHIS_NOCSP
AccessionPrimary (citable) accession number: P48846
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents