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P48836 (VATG_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 121. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
V-type proton ATPase subunit G

Short name=V-ATPase subunit G
Alternative name(s):
V-ATPase 13 kDa subunit
Vacuolar proton pump subunit G
Gene names
Name:VMA10
Ordered Locus Names:YHR039C-A
ORF Names:YHR039BC, YHR039C-B
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length114 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subunit structure

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e).

Miscellaneous

Present with 2280 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the V-ATPase G subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.5
Chain2 – 114113V-type proton ATPase subunit G
PRO_0000192916

Amino acid modifications

Modified residue21N-acetylserine Ref.5

Secondary structure

......... 114
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P48836 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 259660D440A933D0

FASTA11412,713
        10         20         30         40         50         60 
MSQKNGIATL LQAEKEAHEI VSKARKYRQD KLKQAKTDAA KEIDSYKIQK DKELKEFEQK 

        70         80         90        100        110 
NAGGVGELEK KAEAGVQGEL AEIKKIAEKK KDDVVKILIE TVIKPSAEVH INAL 

« Hide

References

« Hide 'large scale' references
[1]"The Saccharomyces cerevisiae VMA10 is an intron-containing gene encoding a novel 13-kDa subunit of vacuolar H(+)-ATPase."
Supekova L., Supek F., Nelson N.
J. Biol. Chem. 270:13726-13732(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 5-15; 57-65 AND 71-84.
Strain: ATCC 200060 / W303.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U21240 mRNA. Translation: AAA74570.1.
U00062 Genomic DNA. Translation: AAB68921.1.
BK006934 Genomic DNA. Translation: DAA06731.1.
PIRS70777.
RefSeqNP_011905.1. NM_001180027.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2K88NMR-A2-58[»]
2KWYNMR-A61-101[»]
4DL0X-ray2.90G/K1-114[»]
4EFAX-ray2.82G1-114[»]
ProteinModelPortalP48836.
SMRP48836. Positions 2-106.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36471. 33 interactions.
DIPDIP-2720N.
IntActP48836. 3 interactions.
MINTMINT-492687.
STRING4932.YHR039C-A.

Protein family/group databases

TCDB3.A.2.2.3. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Proteomic databases

PaxDbP48836.
PeptideAtlasP48836.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR039C-A; YHR039C-A; YHR039C-A.
GeneID856435.
KEGGsce:YHR039C-A.

Organism-specific databases

CYGDYHR039c-a.
SGDS000002100. VMA10.

Phylogenomic databases

eggNOGNOG272364.
GeneTreeENSGT00390000011172.
HOGENOMHOG000186416.
KOK02152.
OMAHPNYRIT.
OrthoDBEOG7HHX5N.

Enzyme and pathway databases

BioCycYEAST:G3O-31242-MONOMER.

Gene expression databases

GenevestigatorP48836.

Family and domain databases

InterProIPR005124. V-ATPase_G.
[Graphical view]
PANTHERPTHR12713. PTHR12713. 1 hit.
TIGRFAMsTIGR01147. V_ATP_synt_G. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP48836.
NextBio982033.

Entry information

Entry nameVATG_YEAST
AccessionPrimary (citable) accession number: P48836
Secondary accession number(s): D3DKY7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references