V-type proton ATPase subunit G - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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P48836 (VATG_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 111. History...

Clusters with 100%, 90%, 50% identity |

Documents (4) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
V-type proton ATPase subunit G
Short name=V-ATPase subunit G

Alternative name(s):
V-ATPase 13 kDa subunit
Vacuolar proton pump subunit G

Gene names

Name:	VMA10
Ordered Locus Names:	YHR039C-A
ORF Names:	YHR039BC, YHR039C-B

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	114 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit structure	V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e).
Miscellaneous	Present with 2280 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the V-ATPase G subunit family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	vacuolar acidification Traceable author statement PubMed 10224039 PubMed 9442887. Source: SGD
Cellular_component	fungal-type vacuole membrane Inferred from direct assay PubMed 22842922. Source: SGD vacuolar proton-transporting V-type ATPase, V1 domain Inferred from direct assay PubMed 16774922. Source: SGD
Molecular_function	proton-transporting ATPase activity, rotational mechanism Traceable author statement PubMed 10224039 PubMed 9442887. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 114

114

V-type proton ATPase subunit G

PRO_0000192916

Secondary structure

114

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P48836 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 259660D440A933D0
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FASTA

114

12,713

        10         20         30         40         50         60 
MSQKNGIATL LQAEKEAHEI VSKARKYRQD KLKQAKTDAA KEIDSYKIQK DKELKEFEQK 

        70         80         90        100        110 
NAGGVGELEK KAEAGVQGEL AEIKKIAEKK KDDVVKILIE TVIKPSAEVH INAL

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Saccharomyces cerevisiae VMA10 is an intron-containing gene encoding a novel 13-kDa subunit of vacuolar H(+)-ATPase." Supekova L., Supek F., Nelson N. J. Biol. Chem. 270:13726-13732(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 5-15; 57-65 AND 71-84. Strain: ATCC 200060 / W303.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U21240 mRNA. Translation: AAA74570.1.
U00062 Genomic DNA. Translation: AAB68921.1.
BK006934 Genomic DNA. Translation: DAA06731.1.

PIR

S70777.

RefSeq

NP_011905.1. NM_001180027.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2K88	NMR	-	A	2-58	[»]
2KWY	NMR	-	A	61-101	[»]
4DL0	X-ray	2.90	G/K	1-114	[»]
4EFA	X-ray	2.82	G	1-114	[»]

ProteinModelPortal

P48836.

SMR

P48836. Positions 2-106.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-2720N.

IntAct

P48836. 3 interactions.

MINT

MINT-492687.

STRING

4932.YHR039C-A.

Protein family/group databases

TCDB

3.A.2.2.3. H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) superfamily.

Proteomic databases

PaxDb

P48836.

PeptideAtlas

P48836.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YHR039C-A; YHR039C-A; YHR039C-A.

GeneID

856435.

KEGG

sce:YHR039C-A.

Organism-specific databases

CYGD

YHR039c-a.

SGD

S000002100. VMA10.

Phylogenomic databases

eggNOG

NOG272364.

GeneTree

ENSGT00390000011172.

HOGENOM

HOG000186416.

K02152.

OMA

SQKNGIA.

OrthoDB

EOG4B0203.

Gene expression databases

Genevestigator

P48836.

GermOnline

YHR039C-A. Saccharomyces cerevisiae.

Family and domain databases

InterPro

IPR005124. V-ATPase_G.
[Graphical view]

PANTHER

PTHR12713. PTHR12713. 1 hit.

Pfam

PF03179. V-ATPase_G. 1 hit.
[Graphical view]

TIGRFAMs

TIGR01147. V_ATP_synt_G. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P48836.

NextBio

982033.

Entry information

Entry name

VATG_YEAST

Accession

Primary (citable) accession number: P48836
Secondary accession number(s): D3DKY7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 111 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents