ID   BGL1_ASPAC              Reviewed;         860 AA.
AC   P48825;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   16-JUN-2009, entry version 43.
DE   RecName: Full=Beta-glucosidase 1;
DE            EC=3.2.1.21;
DE   AltName: Full=Gentiobiase;
DE   AltName: Full=Cellobiase;
DE   AltName: Full=Beta-D-glucoside glucohydrolase;
DE   Flags: Precursor;
OS   Aspergillus aculeatus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae;
OC   mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5053;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=F-50;
RX   MEDLINE=97082984; PubMed=8964516; DOI=10.1016/0378-1119(96)00179-5;
RA   Kawaguchi T., Enoki T., Tsurumaki S., Sumitani J., Ueda M., Ooi T.,
RA   Arai M.;
RT   "Cloning and sequencing of the cDNA encoding beta-glucosidase 1 from
RT   Aspergillus aculeatus.";
RL   Gene 173:287-288(1996).
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of terminal, non-reducing beta-D-
CC       glucosyl residues with release of beta-D-glucose.
CC   -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
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DR   EMBL; D64088; BAA10968.1; -; mRNA.
DR   PIR; JC4939; JC4939.
DR   CAZy; GH3; Glycoside Hydrolase Family 3.
DR   BRENDA; 3.2.1.21; 97085.
DR   GO; GO:0008422; F:beta-glucosidase activity; IEA:EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR019800; Glyco_hydro_3_AS.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   Gene3D; G3DSA:3.20.20.300; Glyco_hydro_3_N; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE   2: Evidence at transcript level;
KW   Carbohydrate metabolism; Cellulose degradation; Glycoprotein;
KW   Glycosidase; Hydrolase; Polysaccharide degradation; Signal.
FT   SIGNAL        1     19       Potential.
FT   CHAIN        20    860       Beta-glucosidase 1.
FT                                /FTId=PRO_0000011776.
FT   ACT_SITE    280    280       By similarity.
FT   CARBOHYD     61     61       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    211    211       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    252    252       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    315    315       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    322    322       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    354    354       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    387    387       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    442    442       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    523    523       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    542    542       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    564    564       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    658    658       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    668    668       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    690    690       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    712    712       N-linked (GlcNAc...) (Potential).
SQ   SEQUENCE   860 AA;  93053 MW;  4B484778B00FC694 CRC64;
     MKLSWLEAAA LTAASVVSAD ELAFSPPFYP SPWANGQGEW AEAYQRAVAI VSQMTLDEKV
     NLTTGTGWEL EKCVGQTGGV PRLNIGGMCL QDSPLGIRDS DYNSAFPAGV NVAATWDKNL
     AYLRGQAMGQ EFSDKGIDVQ LGPAAGPLGR SPDGGRNWEG FSPDPALTGV LFAETIKGIQ
     DAGVVATAKH YILNEQEHFR QVAEAAGYGF NISDTISSNV DDKTIHEMYL WPFADAVRAG
     VGAIMCSYNQ INNSYGCQNS YTLNKLLKAE LGFQGFVMSD WGAHHSGVGS ALAGLDMSMP
     GDITFDSATS FWGTNLTIAV LNGTVPQWRV DDMAVRIMAA YYKVGRDRLY QPPNFSSWTR
     DEYGFKYFYP QEGPYEKVNH FVNVQRNHSE VIRKLGADST VLLKNNNALP LTGKERKVAI
     LGEDAGSNSY GANGCSDRGC DNGTLAMAWG SGTAEFPYLV TPEQAIQAEV LKHKGSVYAI
     TDNWALSQVE TLAKQASVSL VFVNSDAGEG YISVDGNEGD RNNLTLWKNG DNLIKAAANN
     CNNTIVVIHS VGPVLVDEWY DHPNVTAILW AGLPGQESGN SLADVLYGRV NPGAKSPFTW
     GKTREAYGDY LVRELNNGNG APQDDFSEGV FIDYRGFDKR NETPIYEFGH GLSYTTFNYS
     GLHIQVLNAS SNAQVATETG AAPTFGQVGN ASDYVYPEGL TRISKFIYPW LNSTDLKASS
     GDPYYGVDTA EHVPEGATDG SPQPVLPAGG GSGGNPRLYD ELIRVSVTVK NTGRVAGDAV
     PQLYVSLGGP NEPKVVLRKF DRLTLKPSEE TVWTTTLTRR DLSNWDVAAQ DWVITSYPKK
     VHVGSSSRQL PLHAALPKVQ
//