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P48825

- BGL1_ASPAC

UniProt

P48825 - BGL1_ASPAC

Protein

Beta-glucosidase 1

Gene
N/A
Organism
Aspergillus aculeatus
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei280 – 2801By similarity

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    UniPathwayiUPA00696.

    Protein family/group databases

    CAZyiGH3. Glycoside Hydrolase Family 3.
    mycoCLAPiBGL3A_ASPAC.
    BGL3A_ASPSA.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-glucosidase 1 (EC:3.2.1.21)
    Alternative name(s):
    Beta-D-glucoside glucohydrolase
    Cellobiase
    Gentiobiase
    OrganismiAspergillus aculeatus
    Taxonomic identifieri5053 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 860841Beta-glucosidase 1PRO_0000011776Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi61 – 611N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi211 – 2111N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi252 – 2521N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi315 – 3151N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi322 – 3221N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi354 – 3541N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi387 – 3871N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi442 – 4421N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi523 – 5231N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi542 – 5421N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi564 – 5641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi658 – 6581N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi668 – 6681N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi690 – 6901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi712 – 7121N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Structurei

    Secondary structure

    1
    860
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi38 – 403
    Helixi41 – 5111
    Helixi56 – 638
    Beta strandi70 – 778
    Helixi81 – 833
    Beta strandi89 – 913
    Helixi109 – 1157
    Helixi118 – 13417
    Beta strandi138 – 1403
    Helixi157 – 1593
    Helixi165 – 18117
    Beta strandi185 – 1928
    Helixi202 – 2076
    Beta strandi217 – 2193
    Helixi222 – 2276
    Turni228 – 2303
    Helixi231 – 2388
    Beta strandi243 – 2464
    Beta strandi248 – 2514
    Helixi256 – 2583
    Helixi260 – 2634
    Helixi264 – 2707
    Beta strandi275 – 2795
    Helixi288 – 2936
    Beta strandi297 – 3048
    Helixi314 – 3218
    Helixi327 – 34317
    Helixi346 – 3483
    Beta strandi362 – 3676
    Turni368 – 3714
    Beta strandi372 – 3776
    Turni386 – 3883
    Helixi389 – 39810
    Beta strandi401 – 4077
    Beta strandi416 – 4227
    Helixi423 – 4253
    Helixi436 – 4383
    Beta strandi449 – 4524
    Helixi462 – 47211
    Beta strandi476 – 4805
    Helixi486 – 49510
    Beta strandi497 – 5059
    Beta strandi517 – 5204
    Helixi530 – 54011
    Beta strandi542 – 55211
    Turni557 – 5615
    Beta strandi565 – 5706
    Helixi575 – 5773
    Helixi578 – 5869
    Beta strandi602 – 6043
    Helixi605 – 6073
    Beta strandi623 – 6253
    Turni627 – 6304
    Helixi634 – 6396
    Beta strandi657 – 66610
    Helixi691 – 6944
    Beta strandi711 – 7144
    Helixi716 – 7205
    Turni723 – 7264
    Helixi729 – 7324
    Turni735 – 7384
    Beta strandi750 – 7545
    Helixi756 – 7594
    Beta strandi761 – 77111
    Beta strandi773 – 7753
    Beta strandi777 – 7793
    Beta strandi782 – 7865
    Beta strandi796 – 8005
    Beta strandi803 – 8053
    Beta strandi810 – 8189
    Helixi819 – 8224
    Beta strandi824 – 8263
    Turni827 – 8304
    Beta strandi831 – 8333
    Beta strandi840 – 8467
    Beta strandi852 – 8554

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4IIBX-ray1.80A/B20-860[»]
    4IICX-ray1.90A/B20-860[»]
    4IIDX-ray2.30A/B20-860[»]
    4IIEX-ray2.00A/B20-860[»]
    4IIFX-ray2.45A/B20-860[»]
    4IIGX-ray2.30A/B20-860[»]
    4IIHX-ray2.00A/B20-860[»]
    ProteinModelPortaliP48825.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 3 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProiIPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR019800. Glyco_hydro_3_AS.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR30620. PTHR30620. 1 hit.
    PfamiPF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view]
    PRINTSiPR00133. GLHYDRLASE3.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 2 hits.
    PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P48825-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLSWLEAAA LTAASVVSAD ELAFSPPFYP SPWANGQGEW AEAYQRAVAI    50
    VSQMTLDEKV NLTTGTGWEL EKCVGQTGGV PRLNIGGMCL QDSPLGIRDS 100
    DYNSAFPAGV NVAATWDKNL AYLRGQAMGQ EFSDKGIDVQ LGPAAGPLGR 150
    SPDGGRNWEG FSPDPALTGV LFAETIKGIQ DAGVVATAKH YILNEQEHFR 200
    QVAEAAGYGF NISDTISSNV DDKTIHEMYL WPFADAVRAG VGAIMCSYNQ 250
    INNSYGCQNS YTLNKLLKAE LGFQGFVMSD WGAHHSGVGS ALAGLDMSMP 300
    GDITFDSATS FWGTNLTIAV LNGTVPQWRV DDMAVRIMAA YYKVGRDRLY 350
    QPPNFSSWTR DEYGFKYFYP QEGPYEKVNH FVNVQRNHSE VIRKLGADST 400
    VLLKNNNALP LTGKERKVAI LGEDAGSNSY GANGCSDRGC DNGTLAMAWG 450
    SGTAEFPYLV TPEQAIQAEV LKHKGSVYAI TDNWALSQVE TLAKQASVSL 500
    VFVNSDAGEG YISVDGNEGD RNNLTLWKNG DNLIKAAANN CNNTIVVIHS 550
    VGPVLVDEWY DHPNVTAILW AGLPGQESGN SLADVLYGRV NPGAKSPFTW 600
    GKTREAYGDY LVRELNNGNG APQDDFSEGV FIDYRGFDKR NETPIYEFGH 650
    GLSYTTFNYS GLHIQVLNAS SNAQVATETG AAPTFGQVGN ASDYVYPEGL 700
    TRISKFIYPW LNSTDLKASS GDPYYGVDTA EHVPEGATDG SPQPVLPAGG 750
    GSGGNPRLYD ELIRVSVTVK NTGRVAGDAV PQLYVSLGGP NEPKVVLRKF 800
    DRLTLKPSEE TVWTTTLTRR DLSNWDVAAQ DWVITSYPKK VHVGSSSRQL 850
    PLHAALPKVQ 860
    Length:860
    Mass (Da):93,053
    Last modified:February 1, 1996 - v1
    Checksum:i4B484778B00FC694
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D64088 mRNA. Translation: BAA10968.1.
    PIRiJC4939.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D64088 mRNA. Translation: BAA10968.1 .
    PIRi JC4939.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4IIB X-ray 1.80 A/B 20-860 [» ]
    4IIC X-ray 1.90 A/B 20-860 [» ]
    4IID X-ray 2.30 A/B 20-860 [» ]
    4IIE X-ray 2.00 A/B 20-860 [» ]
    4IIF X-ray 2.45 A/B 20-860 [» ]
    4IIG X-ray 2.30 A/B 20-860 [» ]
    4IIH X-ray 2.00 A/B 20-860 [» ]
    ProteinModelPortali P48825.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi P48825.
    ChEMBLi CHEMBL3493.

    Protein family/group databases

    CAZyi GH3. Glycoside Hydrolase Family 3.
    mycoCLAPi BGL3A_ASPAC.
    BGL3A_ASPSA.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00696 .

    Family and domain databases

    Gene3Di 3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProi IPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR019800. Glyco_hydro_3_AS.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR30620. PTHR30620. 1 hit.
    Pfami PF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00133. GLHYDRLASE3.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 2 hits.
    PROSITEi PS00775. GLYCOSYL_HYDROL_F3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of the cDNA encoding beta-glucosidase 1 from Aspergillus aculeatus."
      Kawaguchi T., Enoki T., Tsurumaki S., Sumitani J., Ueda M., Ooi T., Arai M.
      Gene 173:287-288(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: F-50.

    Entry informationi

    Entry nameiBGL1_ASPAC
    AccessioniPrimary (citable) accession number: P48825
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3