P48790 (XYLA_CLOSR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylosidase/arabinosidase

Including the following 2 domains:

1. Beta-xylosidase
   EC=3.2.1.37
   Alternative name(s):
   1,4-beta-D-xylan xylohydrolase
   Xylan 1,4-beta-xylosidase
2. Alpha-N-arabinofuranosidase
   Short name=Arabinosidase
   EC=3.2.1.55

Gene names

Name:

xylA

Organism

Clostridium stercorarium

Taxonomic identifier

1510 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Ruminococcaceae › unclassified Ruminococcaceae

Protein attributes

Sequence length	473 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Subunit structure	Homotetramer.
Sequence similarities	Belongs to the glycosyl hydrolase 43 family.

Ontologies

Keywords
Biological process	Xylan degradation
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing Multifunctional enzyme
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	alpha-N-arabinofuranosidase activity Inferred from electronic annotation. Source: EC xylan 1,4-beta-xylosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 473	473	Xylosidase/arabinosidase		PRO_0000057695

Sequences

	Sequence		Length	Mass (Da)
	P48790 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: CDA34CE9DEBB2399	FASTA	473	53,341
	10 20 30 40 50 60 MRKQRFNPYL PSWEYIPDAE PYVFNGRVYI YGSHDRFNGH AFCLNDYVCW SAPVDDLSEW 70 80 90 100 110 120 RYEGVIYRKT DDPLNPDGRM CLYAPDVTLG PDGRYYLYYV LDKVPVVSVA VCDTPAGKYE 130 140 150 160 170 180 FYGYVRYADG TRLGEREGDW PQFDPAVLTE GERTYLYTGF CPKGDKSRKG AMATVLGPDM 190 200 210 220 230 240 LTVVEEPVII VPSEPYSRGS GFEGHEFFEA PSIRKKGDTY YFIYSSVVMH ELCYATSKHP 250 260 270 280 290 300 TKGFKYGGVI VSNCDLHIDS YKPAEKPMYY GGNNHGSIVE INGEWYIFYH RHTNGTSFSR 310 320 330 340 350 360 QGCMEKIKIL EDGSIPQVEM TSCGSADEPL PGRGEYPAYI ACNLFCGEES VYTDLTGAWM 370 380 390 400 410 420 NNQFPKITQD GKDGDEEPGY IANMKDSATA GFKYFDCKGI KSVKIKVRGY CRGVFEVKTS 430 440 450 460 470 WNGEVLGKIP VEFSNIWTEF SASIPIPDGI HALYFTYRGS GSASLKSFTL CTD

References

[1]

"Nucleotide sequence of the Clostridium stercorarium xylA gene encoding a bifunctional protein with beta-D-xylosidase and alpha-L-arabinofuranosidase activities, and properties of the translated product." Sakka K., Yoshikawa K., Kojima Y., Karita S., Ohmiya K., Shimada K. Biosci. Biotechnol. Biochem. 57:268-272(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D13268 Genomic DNA. Translation: BAA02527.1.
PIR	JQ1936.
3D structure databases
ProteinModelPortal	P48790.
ModBase	Search...
Protein family/group databases
CAZy	GH43. Glycoside Hydrolase Family 43.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.115.10.20. 1 hit.
InterPro	IPR006710. Glyco_hydro_43. IPR023296. Glyco_hydro_beta-prop. [Graphical view]
PANTHER	PTHR22925. PTHR22925. 1 hit.
Pfam	PF04616. Glyco_hydro_43. 1 hit. [Graphical view]
SUPFAM	SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
ProtoNet	Search...

Entry information

Entry name

XYLA_CLOSR

Accession

Primary (citable) accession number: P48790

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program