P48789 (XYNA_PRERU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase A
Short name=Xylanase A
EC=3.2.1.8

Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:

xynA

Organism

Prevotella ruminicola (Bacteroides ruminicola)

Taxonomic identifier

839 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Bacteroidia › Bacteroidales › Prevotellaceae › Prevotella

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 369	349	Endo-1,4-beta-xylanase A		PRO_0000007976
Sites
	Active site	156	1	Proton donor By similarity
	Active site	261	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	P48789 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: EFDBB3E9D77F92D2	FASTA	369	42,524
	10 20 30 40 50 60 MRKLTQFCLG LMLLPIAAVA QNQPTMKDVL GKYFLVGTAL NSHQIWTHDP KIVHAITDNF 70 80 90 100 110 120 NSVVAENCMK GEIIHPEEDY YDWHDADQLV KFAEQHKMTV HGHCLVWHSQ APKWMFTDKE 130 140 150 160 170 180 GKEVTREVLI DRMYHHITNV VKRYKGKIKG WDVVNEAILD NGEYRQSPYY KIIGPDFIKL 190 200 210 220 230 240 AFIFAHQADP DAELYYNDYS MSIPAKRNAV VKLVKELKAA GCRIDAVGMQ SHNGFNYPNL 250 260 270 280 290 300 EDYENSIKAF IAAGVDVQFT ELDVNMLPNP KSFGGAEISQ NYKYNKELNP YVNGLTKAAQ 310 320 330 340 350 360 KTFDQQYLSF FKIYRKYVDH IKRVTVWGVD DGSSWLNGWP VPGRTNYGLL IDRNYKVKPV VKEIIKLYE

References

[1]

"A xylan hydrolase gene cluster in Prevotella ruminicola B(1)4: sequence relationships, synergistic interactions, and oxygen sensitivity of a novel enzyme with exoxylanase and beta-(1,4)-xylosidase activities." Gasparic A., Martin J., Daniel A.S., Flint H.J. Appl. Environ. Microbiol. 61:2958-2964(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: B14.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49241 Genomic DNA. Translation: CAA89207.1.
3D structure databases
ProteinModelPortal	P48789.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00114.
Family and domain databases
Gene3D	3.20.20.80. 1 hit.
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_PRERU

Accession

Primary (citable) accession number: P48789

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program