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P48640 (GSHRP_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione reductase, chloroplastic

Short name=GR
Short name=GRase
EC=1.8.1.7
Gene names
Name:GR
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length544 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Maintains high levels of reduced glutathione in the chloroplast.

Catalytic activity

2 glutathione + NADP+ = glutathione disulfide + NADPH.

Cofactor

Binds 1 FAD per subunit By similarity.

Subcellular location

Plastidchloroplast Potential.

Miscellaneous

The active site is a redox-active disulfide bond.

Sequence similarities

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 5252Chloroplast Potential
Chain53 – 544492Glutathione reductase, chloroplastic
PRO_0000030282

Regions

Nucleotide binding105 – 1139FAD By similarity

Sites

Active site5071Proton acceptor By similarity
Binding site2691NADP By similarity
Binding site2751NADP By similarity

Amino acid modifications

Disulfide bond113 ↔ 118Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
P48640 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 7A71449EA21CE639

FASTA54458,783
        10         20         30         40         50         60 
MATSLSVSPS LSLNTLFIAK ALPLSRPSFL SLPLPKSLLS LSTRRRTFIV RAESQNGRDP 

        70         80         90        100        110        120 
VPAHYDFDLF TIGAGSGGVR ARRFAANYGA SVAICELPFS TISSETTGVG GTCVIRGCVP 

       130        140        150        160        170        180 
KKLLVYASKF SHEFEESNGF GWRYDSEPKH DWSSFIANKN AELQRLTGIY KNILNNAGVK 

       190        200        210        220        230        240 
LIEGHGKMID PHTVDVNGKL YSAKHILVAV GGRPFIPDIP GKELAIDSDA ALDLPTKPVK 

       250        260        270        280        290        300 
IAIVGGGYIA LEFAGIFNGL KSEVHVFIRQ KKVLRGFDEE IRDFVEEQMS VRGIEFHTEE 

       310        320        330        340        350        360 
SPQAITKSAD GSFSLKTNKG TVDGFSHIMF ATGRRPNTQN LGLESVGVKL AKDGAIEVDE 

       370        380        390        400        410        420 
YSQTSVYSIW AVGDVTNRIN LTPVALMEGG ALVKTLFQDN PTKPDYRAVP SAVFSQPPIG 

       430        440        450        460        470        480 
QVGLTEEQAV QQYGDIDIFT ANFRPLKATL SGLPDRVFMK LVVCAKTNEV LGLHMCGEDA 

       490        500        510        520        530        540 
PEIVQGFAVA LKARLTKADF DATVGIHPSA AEEFVTMRTP TRKIRKSESS EGKSGSQAKA 


AAGV 

« Hide

References

[1]"Soybean root nodule cDNA encoding glutathione reductase."
Tang X., Webb M.A.
Plant Physiol. 104:1081-1082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Root nodule.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L11632 mRNA. Translation: AAA33962.1.
PIRT07155.
RefSeqNP_001238006.1. NM_001251077.1.
UniGeneGma.32269.

3D structure databases

ProteinModelPortalP48640.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID547793.
KEGGgmx:547793.

Gene expression databases

GenevestigatorP48640.

Family and domain databases

Gene3D3.30.390.30. 1 hit.
InterProIPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR006324. Glut-diS_reduct.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR012999. Pyr_OxRdtase_I_AS.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
SUPFAMSSF55424. SSF55424. 1 hit.
TIGRFAMsTIGR01424. gluta_reduc_2. 1 hit.
PROSITEPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSHRP_SOYBN
AccessionPrimary (citable) accession number: P48640
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families