Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S25

Gene

RpS25

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S25
Gene namesi
Name:RpS25
Synonyms:RpS31
ORF Names:CG6684
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0086472. RpS25.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001928771 – 11740S ribosomal protein S25Add BLAST117

Proteomic databases

PaxDbiP48588.
PRIDEiP48588.

Expressioni

Gene expression databases

BgeeiFBgn0086472.
GenevisibleiP48588. DM.

Interactioni

Protein-protein interaction databases

BioGridi66477. 17 interactors.
DIPiDIP-17632N.
IntActiP48588. 14 interactors.
MINTiMINT-943476.
STRINGi7227.FBpp0081845.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AZ1-117[»]
ProteinModelPortaliP48588.
SMRiP48588.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1767. Eukaryota.
COG4901. LUCA.
GeneTreeiENSGT00390000004856.
InParanoidiP48588.
KOiK02975.
OMAiKEVPTFR.
OrthoDBiEOG091G134K.
PhylomeDBiP48588.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR004977. Ribosomal_S25.
IPR036388. WH-like_DNA-bd_sf.
PANTHERiPTHR12850. PTHR12850. 1 hit.
PfamiView protein in Pfam
PF03297. Ribosomal_S25. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012268. Ribosomal_S25. 1 hit.

Sequencei

Sequence statusi: Complete.

P48588-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKKDAKSS AKQPQKTQKK KEGSGGGKAK KKKWSKGKVR DKLNNQVLFD
60 70 80 90 100
KATYEKLYKE VPAYKLITPS VVSERLKIRG SLAKRALIEL REKGLIKQVV
110
QHHSQVIYTR ATKGDEA
Length:117
Mass (Da):13,201
Last modified:August 15, 2003 - v3
Checksum:i1EBE36B8FD8896D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti83A → D in AAA03464 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAN13495.1.
AY071076 mRNA. Translation: AAL48698.1.
BT050549 mRNA. Translation: ACJ13256.1.
U03289 Unassigned DNA. Translation: AAA03464.1.
RefSeqiNP_524315.2. NM_079591.6.
NP_731544.1. NM_169376.3.
UniGeneiDm.1146.

Genome annotation databases

EnsemblMetazoaiFBtr0082369; FBpp0081845; FBgn0086472.
FBtr0082370; FBpp0081846; FBgn0086472.
GeneIDi41343.
KEGGidme:Dmel_CG6684.

Similar proteinsi

Entry informationi

Entry nameiRS25_DROME
AccessioniPrimary (citable) accession number: P48588
Secondary accession number(s): B6IDV9
, Q0KI84, Q8SZ71, Q9VGS0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 15, 2003
Last modified: October 25, 2017
This is version 124 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families