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P48558 (YN45_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized vacuolar membrane protein YNL305C
Gene names
Ordered Locus Names:YNL305C
ORF Names:N0405
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Vacuole membrane; Multi-pass membrane protein Ref.5.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297Uncharacterized vacuolar membrane protein YNL305C
PRO_0000203369

Regions

Topological domain1 – 5353Vacuolar Potential
Transmembrane54 – 7421Helical; Potential
Topological domain75 – 8511Cytoplasmic Potential
Transmembrane86 – 10621Helical; Potential
Topological domain107 – 14640Vacuolar Potential
Transmembrane147 – 16721Helical; Potential
Topological domain168 – 1714Cytoplasmic Potential
Transmembrane172 – 19221Helical; Potential
Topological domain193 – 20816Vacuolar Potential
Transmembrane209 – 22921Helical; Potential
Topological domain230 – 23910Cytoplasmic Potential
Transmembrane240 – 26021Helical; Potential
Topological domain261 – 27010Vacuolar Potential
Transmembrane271 – 29121Helical; Potential
Topological domain292 – 2976Cytoplasmic Potential

Experimental info

Sequence conflict841S → A in AAT92698. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P48558 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 330784DA17152BB0

FASTA29733,645
        10         20         30         40         50         60 
MSGPPPPYEE QSSHLYGQPA SSQDGNAFIP EDFKYSTVVI SCEPIIRQRF MHKVYSLLSC 

        70         80         90        100        110        120 
QLLASLSFCY WASVSTSLQN FIMSHIALFY ICMVVSLVSC IWLAVSPRPE DYEASVPEPL 

       130        140        150        160        170        180 
LTGSSEEPAQ EQRRLPWYVL SSYKQKLTLL SIFTLSEAYC LSLVTLAYDK DTVLSALLIT 

       190        200        210        220        230        240 
TIVVVGVSLT ALSERFENVL NSATSIYYWL NWGLWIMIGM GLTALLFGWN THSSKFNLLY 

       250        260        270        280        290 
GWLGAILFTA YLFIDTQLIF RKVYPDEEVR CAMMLYLDIV NLFLSILRIL ANSNDDN

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a 30 kb DNA segment from yeast chromosome XIV carrying a ribosomal protein gene cluster, the genes encoding a plasma membrane protein and a subunit of replication factor C, and a novel putative serine/threonine protein kinase gene."
Maurer K.C.T., Urbanus J.H.M., Planta R.J.
Yeast 11:1303-1310(1995) [PubMed: 8553702] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed: 9169873] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U23084 Genomic DNA. Translation: AAC49093.1.
Z71581 Genomic DNA. Translation: CAA96233.1.
AY692679 Genomic DNA. Translation: AAT92698.1.
BK006947 Genomic DNA. Translation: DAA10256.1.
PIRS63281.
RefSeqNP_014094.1. NM_001183143.1.

3D structure databases

ProteinModelPortalP48558.
ModBaseSearch...

Protein-protein interaction databases

IntActP48558. 2 interactions.
STRINGP48558.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL305C; YNL305C; YNL305C.
GeneID855411.
KEGGsce:YNL305C.
NMPDRfig|4932.3.peg.5156.

Organism-specific databases

CYGDYNL305c.
SGDS000005249. YNL305C.

Phylogenomic databases

eggNOGfuNOG09808.
GeneTreeEFGT00050000005815.
HOGENOMHBG595196.
OrthoDBEOG418FXW.

Gene expression databases

ArrayExpressP48558.
GenevestigatorP48558.
GermOnlineYNL305C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR006214. Inhibitor_apoptosis_Bax1.
[Graphical view]
KOK06890.
PANTHERPTHR23291. UPF0005. 1 hit.
PfamPF01027. Bax1-I. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio979256.

Entry information

Entry nameYN45_YEAST
AccessionPrimary (citable) accession number: P48558
Secondary accession number(s): D6W0P0, Q6B2Q1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents