Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot P48558 (YN45_YEAST)

Last modified December 15, 2009. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Uncharacterized vacuolar membrane protein YNL305C
Gene names
Ordered Locus Names: YNL305C
ORF Names: N0405
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Ontologies

Keywords
   Cellular componentMembrane
Vacuole
   DomainTransmembrane
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentfungal-type vacuole Ref.4

Inferred from direct assay. Source: SGD

integral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297Uncharacterized vacuolar membrane protein YNL305C
PRO_0000203369

Regions

Topological domain1 – 5353Vacuolar Potential
Transmembrane54 – 7421 Potential
Topological domain75 – 8511Cytoplasmic Potential
Transmembrane86 – 10621 Potential
Topological domain107 – 14640Vacuolar Potential
Transmembrane147 – 16721 Potential
Topological domain168 – 1714Cytoplasmic Potential
Transmembrane172 – 19221 Potential
Topological domain193 – 20816Vacuolar Potential
Transmembrane209 – 22921 Potential
Topological domain230 – 23910Cytoplasmic Potential
Transmembrane240 – 26021 Potential
Topological domain261 – 27010Vacuolar Potential
Transmembrane271 – 29121 Potential
Topological domain292 – 2976Cytoplasmic Potential

Experimental info

Sequence conflict841S → A in AAT92698. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P48558-1 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 330784DA17152BB0

FASTA29733,645
        10         20         30         40         50         60 
MSGPPPPYEE QSSHLYGQPA SSQDGNAFIP EDFKYSTVVI SCEPIIRQRF MHKVYSLLSC 

        70         80         90        100        110        120 
QLLASLSFCY WASVSTSLQN FIMSHIALFY ICMVVSLVSC IWLAVSPRPE DYEASVPEPL 

       130        140        150        160        170        180 
LTGSSEEPAQ EQRRLPWYVL SSYKQKLTLL SIFTLSEAYC LSLVTLAYDK DTVLSALLIT 

       190        200        210        220        230        240 
TIVVVGVSLT ALSERFENVL NSATSIYYWL NWGLWIMIGM GLTALLFGWN THSSKFNLLY 

       250        260        270        280        290 
GWLGAILFTA YLFIDTQLIF RKVYPDEEVR CAMMLYLDIV NLFLSILRIL ANSNDDN 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a 30 kb DNA segment from yeast chromosome XIV carrying a ribosomal protein gene cluster, the genes encoding a plasma membrane protein and a subunit of replication factor C, and a novel putative serine/threonine protein kinase gene."
Maurer K.C.T., Urbanus J.H.M., Planta R.J.
Yeast 11:1303-1310(1995) [PubMed: 8553702] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed: 9169873] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

U23084 Genomic DNA. Translation: AAC49093.1.
Z71581 Genomic DNA. Translation: CAA96233.1.
AY692679 Genomic DNA. Translation: AAT92698.1.
PIRS63281.
RefSeqNP_014094.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActP48558. 2 interactions.
STRINGP48558.

Genome annotation databases

EnsemblYNL305C; YNL305C; YNL305C; Saccharomyces cerevisiae. [Genome view]
GeneID855411.
KEGGsce:YNL305C.
NMPDRfig|4932.3.peg.5156.

Organism-specific databases

CYGDYNL305c.
SGDS000005249. YNL305C.

Phylogenomic databases

HOGENOMHBG595196.
OMADVASCEL.
OrthoDBEOG9MKPZ9.

Gene expression databases

ArrayExpressP48558.
GenevestigatorP48558.
GermOnlineYNL305C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR006214. UPF0005.
[Graphical view]
PANTHERPTHR23291. UPF0005. 1 hit.
PfamPF01027. UPF0005. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio979256.

Entry information

Entry nameYN45_YEAST
AccessionPrimary (citable) accession number: P48558
Secondary accession number(s): Q6B2Q1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: December 15, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents