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P48490

- PP1_PHAVU

UniProt

P48490 - PP1_PHAVU

Protein

Serine/threonine-protein phosphatase PP1

Gene
N/A
Organism
Phaseolus vulgaris (Kidney bean) (French bean)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi58 – 581Manganese 1By similarity
    Metal bindingi60 – 601Manganese 1By similarity
    Metal bindingi86 – 861Manganese 1By similarity
    Metal bindingi86 – 861Manganese 2By similarity
    Metal bindingi118 – 1181Manganese 2By similarity
    Active sitei119 – 1191Proton donorBy similarity
    Metal bindingi167 – 1671Manganese 2By similarity
    Metal bindingi242 – 2421Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Stress response

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
    OrganismiPhaseolus vulgaris (Kidney bean) (French bean)
    Taxonomic identifieri3885 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaePhaseolus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 314314Serine/threonine-protein phosphatase PP1PRO_0000058810Add
    BLAST

    Expressioni

    Inductioni

    By stress.

    Structurei

    3D structure databases

    ProteinModelPortaliP48490.
    SMRiP48490. Positions 6-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P48490-1 [UniParc]FASTAAdd to Basket

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    MDKAVLDDVI RRLLEGKGGK QVQLSESEIR QLCVHARQIF LSQPILLELR    50
    APMRVCGDIH GQYQDLLRLF EYGGYPPAAN YLFLGDYVDR GKQSLETICL 100
    LLAYKIRYPD KIFLLRGNHE EAKINRIYGF YDECKRRFNV RLWKIFTDCF 150
    NCLPVSALID DKILCMHGGL SPELESLDQI KEIQRPTEIP DSGLLCDLLW 200
    SDPDSSIEGW AESDRGVSCT FGPDVVAEFL DKNDLDLVCR GHQVVEDGYE 250
    FFAKRRLVTI FSAPNYGGEF DNAGALLSVD DSLVCSFEIL KPADRASGSS 300
    SKMNFKKPPK MGKI 314
    Length:314
    Mass (Da):35,547
    Last modified:February 1, 1996 - v1
    Checksum:i601AAD99FDACABC9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48221 mRNA. Translation: CAA88254.1.
    PIRiS60053. S52371.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48221 mRNA. Translation: CAA88254.1 .
    PIRi S60053. S52371.

    3D structure databases

    ProteinModelPortali P48490.
    SMRi P48490. Positions 6-294.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of the cDNA encoding a stress-inducible protein phosphatase 1 (PP1) catalytic subunit from French bean (Phaseolus vulgaris L.)."
      Zimmerlin A., Jupe S.C., Bolwell G.P.
      Plant Mol. Biol. 28:363-368(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPP1_PHAVU
    AccessioniPrimary (citable) accession number: P48490
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3