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Protein

Serine/threonine-protein phosphatase PP1

Gene
N/A
Organism
Phaseolus vulgaris (Kidney bean) (French bean)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi58Manganese 1By similarity1
Metal bindingi60Manganese 1By similarity1
Metal bindingi86Manganese 1By similarity1
Metal bindingi86Manganese 2By similarity1
Metal bindingi118Manganese 2By similarity1
Active sitei119Proton donorBy similarity1
Metal bindingi167Manganese 2By similarity1
Metal bindingi242Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
Biological processStress response
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
OrganismiPhaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifieri3885 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaePhaseolus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000588101 – 314Serine/threonine-protein phosphatase PP1Add BLAST314

Expressioni

Inductioni

By stress.

Structurei

3D structure databases

ProteinModelPortaliP48490
SMRiP48490
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
IPR031675 STPPase_N
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF16891 STPPase_N, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P48490-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKAVLDDVI RRLLEGKGGK QVQLSESEIR QLCVHARQIF LSQPILLELR
60 70 80 90 100
APMRVCGDIH GQYQDLLRLF EYGGYPPAAN YLFLGDYVDR GKQSLETICL
110 120 130 140 150
LLAYKIRYPD KIFLLRGNHE EAKINRIYGF YDECKRRFNV RLWKIFTDCF
160 170 180 190 200
NCLPVSALID DKILCMHGGL SPELESLDQI KEIQRPTEIP DSGLLCDLLW
210 220 230 240 250
SDPDSSIEGW AESDRGVSCT FGPDVVAEFL DKNDLDLVCR GHQVVEDGYE
260 270 280 290 300
FFAKRRLVTI FSAPNYGGEF DNAGALLSVD DSLVCSFEIL KPADRASGSS
310
SKMNFKKPPK MGKI
Length:314
Mass (Da):35,547
Last modified:February 1, 1996 - v1
Checksum:i601AAD99FDACABC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48221 mRNA Translation: CAA88254.1
PIRiS60053 S52371

Similar proteinsi

Entry informationi

Entry nameiPP1_PHAVU
AccessioniPrimary (citable) accession number: P48490
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health