P48490 (PP1_PHAVU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Serine/threonine-protein phosphatase PP1 EC=3.1.3.16
Organism	Phaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifier	3885 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Phaseolus

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 1 iron ion per subunit By similarity. Binds 1 manganese ion per subunit By similarity.
Induction	By stress.
Sequence similarities	Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Keywords
Biological process	Stress response
Ligand	Iron Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Gene Ontology (GO)
Biological_process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	Serine/threonine-protein phosphatase PP1		PRO_0000058810
Sites
	Active site	119	1	Proton donor By similarity
	Metal binding	58	1	Iron By similarity
	Metal binding	60	1	Iron By similarity
	Metal binding	86	1	Iron By similarity
	Metal binding	86	1	Manganese By similarity
	Metal binding	118	1	Manganese By similarity
	Metal binding	167	1	Manganese By similarity
	Metal binding	242	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	P48490 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 601AAD99FDACABC9	FASTA	314	35,547
	10 20 30 40 50 60 MDKAVLDDVI RRLLEGKGGK QVQLSESEIR QLCVHARQIF LSQPILLELR APMRVCGDIH 70 80 90 100 110 120 GQYQDLLRLF EYGGYPPAAN YLFLGDYVDR GKQSLETICL LLAYKIRYPD KIFLLRGNHE 130 140 150 160 170 180 EAKINRIYGF YDECKRRFNV RLWKIFTDCF NCLPVSALID DKILCMHGGL SPELESLDQI 190 200 210 220 230 240 KEIQRPTEIP DSGLLCDLLW SDPDSSIEGW AESDRGVSCT FGPDVVAEFL DKNDLDLVCR 250 260 270 280 290 300 GHQVVEDGYE FFAKRRLVTI FSAPNYGGEF DNAGALLSVD DSLVCSFEIL KPADRASGSS 310 SKMNFKKPPK MGKI

References

[1]	"Molecular cloning of the cDNA encoding a stress-inducible protein phosphatase 1 (PP1) catalytic subunit from French bean (Phaseolus vulgaris L.)." Zimmerlin A., Jupe S.C., Bolwell G.P. Plant Mol. Biol. 28:363-368(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z48221 mRNA. Translation: CAA88254.1.
PIR	S52371. S60053.
3D structure databases
ProteinModelPortal	P48490.
SMR	P48490. Positions 6-294.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR004843. Metallo_PEstase_dom. IPR006186. Ser/Thr-sp_prot-phosphatase. [Graphical view]
Pfam	PF00149. Metallophos. 1 hit. [Graphical view]
PRINTS	PR00114. STPHPHTASE.
SMART	SM00156. PP2Ac. 1 hit. [Graphical view]
PROSITE	PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PP1_PHAVU

Accession

Primary (citable) accession number: P48490

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program