Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P48490 (PP1_PHAVU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1

EC=3.1.3.16
OrganismPhaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifier3885 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaePhaseolus

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Induction

By stress.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Keywords
   Biological processStress response
   LigandManganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 314314Serine/threonine-protein phosphatase PP1
PRO_0000058810

Sites

Active site1191Proton donor By similarity
Metal binding581Manganese 1 By similarity
Metal binding601Manganese 1 By similarity
Metal binding861Manganese 1 By similarity
Metal binding861Manganese 2 By similarity
Metal binding1181Manganese 2 By similarity
Metal binding1671Manganese 2 By similarity
Metal binding2421Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P48490 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 601AAD99FDACABC9

FASTA31435,547
        10         20         30         40         50         60 
MDKAVLDDVI RRLLEGKGGK QVQLSESEIR QLCVHARQIF LSQPILLELR APMRVCGDIH 

        70         80         90        100        110        120 
GQYQDLLRLF EYGGYPPAAN YLFLGDYVDR GKQSLETICL LLAYKIRYPD KIFLLRGNHE 

       130        140        150        160        170        180 
EAKINRIYGF YDECKRRFNV RLWKIFTDCF NCLPVSALID DKILCMHGGL SPELESLDQI 

       190        200        210        220        230        240 
KEIQRPTEIP DSGLLCDLLW SDPDSSIEGW AESDRGVSCT FGPDVVAEFL DKNDLDLVCR 

       250        260        270        280        290        300 
GHQVVEDGYE FFAKRRLVTI FSAPNYGGEF DNAGALLSVD DSLVCSFEIL KPADRASGSS 

       310 
SKMNFKKPPK MGKI 

« Hide

References

[1]"Molecular cloning of the cDNA encoding a stress-inducible protein phosphatase 1 (PP1) catalytic subunit from French bean (Phaseolus vulgaris L.)."
Zimmerlin A., Jupe S.C., Bolwell G.P.
Plant Mol. Biol. 28:363-368(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z48221 mRNA. Translation: CAA88254.1.
PIRS52371. S60053.

3D structure databases

ProteinModelPortalP48490.
SMRP48490. Positions 6-294.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP1_PHAVU
AccessionPrimary (citable) accession number: P48490
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families