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Protein

Serine/threonine-protein phosphatase PP1

Gene

Os03g0268000

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi75Manganese 1By similarity1
Metal bindingi77Manganese 1By similarity1
Metal bindingi103Manganese 1By similarity1
Metal bindingi103Manganese 2By similarity1
Metal bindingi135Manganese 2By similarity1
Active sitei136Proton donorBy similarity1
Metal bindingi184Manganese 2By similarity1
Metal bindingi259Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
Gene namesi
Ordered Locus Names:Os03g0268000, LOC_Os03g16110
ORF Names:OJ1364E02.17, OJA1364E02.7
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000588091 – 322Serine/threonine-protein phosphatase PP1Add BLAST322

Proteomic databases

PaxDbiP48489.
PRIDEiP48489.

Expressioni

Gene expression databases

ExpressionAtlasiP48489. baseline and differential.
GenevisibleiP48489. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os03g16110.1.

Structurei

3D structure databases

ProteinModelPortaliP48489.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

eggNOGiENOG410IN85. Eukaryota.
ENOG410XPVF. LUCA.
HOGENOMiHOG000172697.
InParanoidiP48489.
OMAiKNKFMAS.
OrthoDBiEOG09360F05.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR031675. STPPase_N.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF16891. STPPase_N. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48489-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAPGAGGQ GGGGMDAVLL DDIIRRLLEV RTARPGKQVQ LSESEIRQLC
60 70 80 90 100
TVSREIFLSQ PNLLELEAPI KICGDIHGQY SDLLRLFEYG GFPPEANYLF
110 120 130 140 150
LGDYVDRGKQ SLETICLLLA YKIKYPENFF LLRGNHECAS INRIYGFYDE
160 170 180 190 200
CKRRFNVRLW KVFTDCFNCL PVAALIDDKI LCMHGGLSPD LTHLDEIKSL
210 220 230 240 250
PRPTDVPDTG LLCDLLWSDP GKDVQGWGMN DRGVSYTFGA DKVSEFLEKH
260 270 280 290 300
DLDLICRAHQ VVEDGYEFFA DRQLVTIFSA PNYCGEFDNA GAMMSVDETL
310 320
MCSFQILKPA ERKGKFMASN KM
Length:322
Mass (Da):36,166
Last modified:June 13, 2006 - v2
Checksum:iF4C8280134836BE7
GO

Sequence cautioni

The sequence AAP06889 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAP06897 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti3 – 11AAPGAGGQG → PRRR (PubMed:10080713).Curated9
Sequence conflicti17A → P in AAA74625 (PubMed:10080713).Curated1
Sequence conflicti25 – 26RR → PP in AAA74625 (PubMed:10080713).Curated2
Sequence conflicti40Q → H in AAA74625 (PubMed:10080713).Curated1
Sequence conflicti51T → S in AAA74625 (PubMed:10080713).Curated1
Sequence conflicti120A → G in AAA74625 (PubMed:10080713).Curated1
Sequence conflicti157V → M in AAA74625 (PubMed:10080713).Curated1
Sequence conflicti199 – 201SLP → RLA in AAA74625 (PubMed:10080713).Curated3
Sequence conflicti215 – 216LL → YF in AAA74625 (PubMed:10080713).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31773 mRNA. Translation: AAA74625.1.
AC135208 Genomic DNA. Translation: AAP06889.1. Sequence problems.
AC139168 Genomic DNA. Translation: AAP06897.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF95164.1.
DP000009 Genomic DNA. Translation: ABF95165.1.
DP000009 Genomic DNA. Translation: ABF95166.1.
AP008209 Genomic DNA. Translation: BAF11583.1.
AP014959 Genomic DNA. Translation: BAS83435.1.
AK073140 mRNA. Translation: BAG93306.1.
PIRiT03304.
UniGeneiOs.9092.

Genome annotation databases

EnsemblPlantsiOS03T0268000-01; OS03T0268000-01; OS03G0268000.
GrameneiOS03T0268000-01; OS03T0268000-01; OS03G0268000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31773 mRNA. Translation: AAA74625.1.
AC135208 Genomic DNA. Translation: AAP06889.1. Sequence problems.
AC139168 Genomic DNA. Translation: AAP06897.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF95164.1.
DP000009 Genomic DNA. Translation: ABF95165.1.
DP000009 Genomic DNA. Translation: ABF95166.1.
AP008209 Genomic DNA. Translation: BAF11583.1.
AP014959 Genomic DNA. Translation: BAS83435.1.
AK073140 mRNA. Translation: BAG93306.1.
PIRiT03304.
UniGeneiOs.9092.

3D structure databases

ProteinModelPortaliP48489.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os03g16110.1.

Proteomic databases

PaxDbiP48489.
PRIDEiP48489.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS03T0268000-01; OS03T0268000-01; OS03G0268000.
GrameneiOS03T0268000-01; OS03T0268000-01; OS03G0268000.

Phylogenomic databases

eggNOGiENOG410IN85. Eukaryota.
ENOG410XPVF. LUCA.
HOGENOMiHOG000172697.
InParanoidiP48489.
OMAiKNKFMAS.
OrthoDBiEOG09360F05.

Gene expression databases

ExpressionAtlasiP48489. baseline and differential.
GenevisibleiP48489. OS.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR031675. STPPase_N.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF16891. STPPase_N. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPP1_ORYSJ
AccessioniPrimary (citable) accession number: P48489
Secondary accession number(s): Q10NJ4, Q84J82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: June 13, 2006
Last modified: November 30, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.