Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P48487

- PP1_BRAOL

UniProt

P48487 - PP1_BRAOL

Protein

Serine/threonine-protein phosphatase PP1

Gene

PP1

Organism
Brassica oleracea (Wild cabbage)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi79 – 791Manganese 1By similarity
    Metal bindingi81 – 811Manganese 1By similarity
    Metal bindingi107 – 1071Manganese 1By similarity
    Metal bindingi107 – 1071Manganese 2By similarity
    Metal bindingi139 – 1391Manganese 2By similarity
    Active sitei140 – 1401Proton donorBy similarity
    Metal bindingi187 – 1871Manganese 2By similarity
    Metal bindingi262 – 2621Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
    Gene namesi
    Name:PP1
    OrganismiBrassica oleracea (Wild cabbage)
    Taxonomic identifieri3712 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 316316Serine/threonine-protein phosphatase PP1PRO_0000058806Add
    BLAST

    Proteomic databases

    PRIDEiP48487.

    Structurei

    3D structure databases

    ProteinModelPortaliP48487.
    SMRiP48487. Positions 22-316.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P48487-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEKPAPEQE QEQTRAMEPA VLDDIIRRLV EFRNTRPGSG KQVHLSEGEI    50
    RQLCAVSKDI FLQQPILLEL EAPIKICGDI HGQYSDLLRL FEYGGFPPDA 100
    NYLFLGDYVD RGKQSLETIC FLLAYKIKYP ENFFLLRGNH ECASINRIYG 150
    FYDECKRRFN VRLWKIFTDC FNCLPVAALI DRILCMHGGI SPELMSLDQI 200
    RSISRPLDIP DSGLVCDLLW SDPSGDVKGW GANDRGVSYT FGADTVAEFL 250
    QKNDMDLICR AHQVVEDGYE FFAERQVVTV FSAPNYCGEF DNAGAMMSID 300
    ESLMCSFQIL KPSEKK 316
    Length:316
    Mass (Da):35,902
    Last modified:February 1, 1996 - v1
    Checksum:i66D5131A3ECA4DF0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X63558 mRNA. Translation: CAA45119.1.
    PIRiS26225.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X63558 mRNA. Translation: CAA45119.1 .
    PIRi S26225.

    3D structure databases

    ProteinModelPortali P48487.
    SMRi P48487. Positions 22-316.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P48487.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization of type 1 serine/threonine phosphatases from Brassica oleracea."
      Rundle S.J., Nasrallah J.B.
      Plant Mol. Biol. 20:367-375(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Flower.

    Entry informationi

    Entry nameiPP1_BRAOL
    AccessioniPrimary (citable) accession number: P48487
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3