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Protein

Serine/threonine-protein phosphatase PP1

Gene

PP1

Organism
Brassica oleracea (Wild cabbage)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi79 – 791Manganese 1By similarity
Metal bindingi81 – 811Manganese 1By similarity
Metal bindingi107 – 1071Manganese 1By similarity
Metal bindingi107 – 1071Manganese 2By similarity
Metal bindingi139 – 1391Manganese 2By similarity
Active sitei140 – 1401Proton donorBy similarity
Metal bindingi187 – 1871Manganese 2By similarity
Metal bindingi262 – 2621Manganese 2By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
Gene namesi
Name:PP1
OrganismiBrassica oleracea (Wild cabbage)
Taxonomic identifieri3712 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 316315Serine/threonine-protein phosphatase PP1PRO_0000058806Add
BLAST

Proteomic databases

PRIDEiP48487.

Structurei

3D structure databases

ProteinModelPortaliP48487.
SMRiP48487. Positions 22-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P48487-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKPAPEQE QEQTRAMEPA VLDDIIRRLV EFRNTRPGSG KQVHLSEGEI
60 70 80 90 100
RQLCAVSKDI FLQQPILLEL EAPIKICGDI HGQYSDLLRL FEYGGFPPDA
110 120 130 140 150
NYLFLGDYVD RGKQSLETIC FLLAYKIKYP ENFFLLRGNH ECASINRIYG
160 170 180 190 200
FYDECKRRFN VRLWKIFTDC FNCLPVAALI DRILCMHGGI SPELMSLDQI
210 220 230 240 250
RSISRPLDIP DSGLVCDLLW SDPSGDVKGW GANDRGVSYT FGADTVAEFL
260 270 280 290 300
QKNDMDLICR AHQVVEDGYE FFAERQVVTV FSAPNYCGEF DNAGAMMSID
310
ESLMCSFQIL KPSEKK
Length:316
Mass (Da):35,902
Last modified:February 1, 1996 - v1
Checksum:i66D5131A3ECA4DF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63558 mRNA. Translation: CAA45119.1.
PIRiS26225.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63558 mRNA. Translation: CAA45119.1.
PIRiS26225.

3D structure databases

ProteinModelPortaliP48487.
SMRiP48487. Positions 22-316.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP48487.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of type 1 serine/threonine phosphatases from Brassica oleracea."
    Rundle S.J., Nasrallah J.B.
    Plant Mol. Biol. 20:367-375(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Flower.

Entry informationi

Entry nameiPP1_BRAOL
AccessioniPrimary (citable) accession number: P48487
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.