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P48483 (PP13_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1 isozyme 3

EC=3.1.3.16
Gene names
Name:TOPP3
Ordered Locus Names:At1g64040
ORF Names:F22C12.20
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Sequence caution

The sequence AAF24566.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 322322Serine/threonine-protein phosphatase PP1 isozyme 3
PRO_0000058799

Sites

Active site1221Proton donor By similarity
Metal binding611Iron By similarity
Metal binding631Iron By similarity
Metal binding891Iron By similarity
Metal binding891Manganese By similarity
Metal binding1211Manganese By similarity
Metal binding1701Manganese By similarity
Metal binding2451Manganese By similarity

Amino acid modifications

Modified residue11N-acetylmethionine By similarity

Sequences

Sequence LengthMass (Da)Tools
P48483 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 644A70BB9F63215C

FASTA32236,215
        10         20         30         40         50         60 
MEDSVVDDVI KRLLGAKNGK TTKQVQLTEA EIKHLCSTAK QIFLTQPNLL ELEAPIKICG 

        70         80         90        100        110        120 
DTHGQFSDLL RLFEYGGYPP AANYLFLGDY VDRGKQSVET ICLLLAYKIK YKENFFLLRG 

       130        140        150        160        170        180 
NHECASINRI YGFYDECKKR YSVRVWKIFT DCFNCLPVAA LIDEKILCMH GGLSPELKHL 

       190        200        210        220        230        240 
DEIRNIPRPA DIPDHGLLCD LLWSDPDKDI EGWGENDRGV SYTFGADKVE EFLQTHDLDL 

       250        260        270        280        290        300 
ICRAHQVVED GYEFFANRQL VTIFSAPNYC GEFDNAGAMM SVDDSLTCSF QILKASEKKG 

       310        320 
NFGFGKNAGR RGTPPRKGGG KG 

« Hide

References

« Hide 'large scale' references
[1]"Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana."
Smith R.D., Walker J.C.
Plant Mol. Biol. 21:307-316(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Arabidopsis PPP family of serine/threonine phosphatases."
Farkas I., Dombradi V., Miskei M., Szabados L., Koncz C.
Trends Plant Sci. 12:169-176(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M93410 mRNA. Translation: AAA32838.1.
AC007764 Genomic DNA. Translation: AAF24566.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34183.1.
AY081338 mRNA. Translation: AAL91227.1.
AY128830 mRNA. Translation: AAM91230.1.
PIRC96665.
S31087.
RefSeqNP_176587.1. NM_105077.3.
UniGeneAt.309.

3D structure databases

ProteinModelPortalP48483.
SMRP48483. Positions 6-294.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G64040.1-P.

Proteomic databases

PaxDbP48483.
PRIDEP48483.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G64040.1; AT1G64040.1; AT1G64040.
GeneID842708.
KEGGath:AT1G64040.

Organism-specific databases

TAIRAT1G64040.

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000172697.
InParanoidP48483.
KOK06269.
OMADECKKRY.
PhylomeDBP48483.
ProtClustDBCLSN2913591.

Enzyme and pathway databases

BioCycARA:AT1G64040-MONOMER.

Gene expression databases

GenevestigatorP48483.

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP13_ARATH
AccessionPrimary (citable) accession number: P48483
Secondary accession number(s): Q9SH54
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names